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Constrained combinatorial optimization problems are frequently reformulated as quadratic unconstrained binary optimization (QUBO) models in order to leverage emerging quantum optimization algorithms such as the Variational Quantum…

Quantum Physics · Physics 2026-04-23 Xin Wei Lee , Hoong Chuin Lau

QRAO (Quantum Random Access Optimization) is a relaxation algorithm that reduces the number of qubits required to solve a problem by encoding multiple variables per qubit using QRAC (Quantum Random Access Code). Reducing the number of…

In materials informatics, searching for chemical materials with desired properties is challenging due to the vastness of the chemical space. Moreover, the high cost of evaluating properties necessitates a search with a few clues. In…

Quantum Physics · Physics 2023-12-18 Mikiya Doi , Yoshihiro Nakao , Takuro Tanaka , Masami Sako , Masayuki Ohzeki

The demand for high-performance computing in machine learning and artificial intelligence has led to the development of specialized hardware accelerators like Tensor Processing Units (TPUs), Graphics Processing Units (GPUs), and…

Machine Learning · Computer Science 2025-09-08 Thore Gerlach , Nico Piatkowski

Quantum computing and modern tensor-based computing have a strong connection, which is especially demonstrated by simulating quantum computations with tensor networks. The other direction is less studied: quantum computing is not often…

Quantum Physics · Physics 2025-09-03 Valter Uotila

Combinatorial optimization problems play a central role in computer science with many real world applications. A number of relevant problems remain computationally difficult to solve as they lie in the NP-hard complexity class. We present a…

Quantum Physics · Physics 2026-05-11 Kapil Goswami , Peter Schmelcher

A quantum annealer heuristically minimizes quadratic unconstrained binary optimization (QUBO) problems, but is limited by the physical hardware in the size and density of the problems it can handle. We have developed a meta-heuristic solver…

Discrete Mathematics · Computer Science 2016-05-20 Gili Rosenberg , Mohammad Vazifeh , Brad Woods , Eldad Haber

We present QUBO.jl, an end-to-end Julia package for working with QUBO (Quadratic Unconstrained Binary Optimization) instances. This tool aims to convert a broad range of JuMP problems for straightforward application in many physics and…

Optimization and Control · Mathematics 2023-09-04 Pedro Maciel Xavier , Pedro Ripper , Tiago Andrade , Joaquim Dias Garcia , Nelson Maculan , David E. Bernal Neira

Practically relevant problems of quadratic optimization often contain multidimensional arrays of variables interconnected by linear constraints, such as equalities and inequalities. The values of each variable depend on its specific meaning…

Optimization and Control · Mathematics 2026-01-27 Alexander M. Semenov , Sergey R. Usmanov , Aleksey K. Fedorov

The increasing complexity of industrial scheduling and transport routing problems motivates the study of alternative optimization formulations and computational paradigms. In this work, we study how higher-order unconstrained binary…

I present a novel use of quantum annealing to solve the Set Splitting Problem using (QUBO) problem formulation. The contribution of the work is in formulating penalty functions that ensure the ground state of the QUBO Hamiltonian…

Quantum Physics · Physics 2025-08-11 Sean Borneman

In this paper we present a novel strategy to solve optimization problems within a hybrid quantum-classical scheme based on quantum annealing, with a particular focus on QUBO problems. The proposed algorithm is based on an iterative…

Quantum Physics · Physics 2020-04-07 Enrico Blanzieri , Davide Pastorello

Recent advancements in quantum annealing hardware and numerous studies in this area suggests that quantum annealers have the potential to be effective in solving unconstrained binary quadratic programming problems. Naturally, one may desire…

Quantum Physics · Physics 2019-03-01 Sahar Karimi , Pooya Ronagh

With the development of quantum computing, the use of quantum algorithms to solve combinatorial optimization problems on quantum computers has become a major research focus. The Quadratic Unconstrained Binary Optimization (QUBO) model…

Computational Engineering, Finance, and Science · Computer Science 2025-04-10 Haoqian Pan , Changhong Lu

The advent of quantum computing processors with possibility to scale beyond experimental capacities magnifies the importance of studying their applications. Combinatorial optimization problems can be one of the promising applications of…

Quantum Physics · Physics 2017-08-18 Ehsan Zahedinejad , Arman Zaribafiyan

This paper develops an algorithmic solution using Ising machines to solve large-scale higher-order binary optimization (HOBO) problems with inequality constraints for resource optimization in wireless communications systems. Quadratic…

Information Theory · Computer Science 2025-09-25 Gan Zheng , Ioannis Krikidis

Data discretization, also known as binning, is a frequently used technique in computer science, statistics, and their applications to biological data analysis. We present a new method for the discretization of real-valued data into a finite…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Elena S. Dimitrova , John J. McGee , Reinhard C. Laubenbacher

Several recent unsupervised learning methods use probabilistic approaches to solve combinatorial optimization (CO) problems based on the assumption of statistically independent solution variables. We demonstrate that this assumption imposes…

Machine Learning · Computer Science 2023-11-27 Sebastian Sanokowski , Wilhelm Berghammer , Sepp Hochreiter , Sebastian Lehner

To run an algorithm on a quantum computer, one must choose an assignment from logical qubits in a circuit to physical qubits on quantum hardware. This task of initial qubit placement, or qubit allocation, is especially important on…

Quantum Physics · Physics 2020-12-01 Bryan Dury , Olivia Di Matteo

With the advent of novel quantum computing technologies, and the knowledge that such technology might be used to fundamentally change computing applications, a prime opportunity has presented itself to investigate the practical application…

Computational Engineering, Finance, and Science · Computer Science 2024-02-13 Kevin Wils , Boyang Chen
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