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Quantitative measurements produced by mass spectrometry proteomics experiments offer a direct way to explore the role of proteins in molecular mechanisms. However, analysis of such data is challenging due to the large proportion of missing…

Methodology · Statistics 2025-01-22 Haeun Moon , Jin-Hong Du , Jing Lei , Kathryn Roeder

Missing data is a common challenge across scientific disciplines. Current imputation methods require the availability of individual data to impute missing values. Often, however, missingness requires using external data for the imputation.…

Methodology · Statistics 2024-10-07 Robert Thiesmeier , Matteo Bottai , Nicola Orsini

BACKGROUND: As databases grow larger, it becomes harder to fully control their collection, and they frequently come with missing values: incomplete observations. These large databases are well suited to train machine-learning models, for…

Machine Learning · Computer Science 2022-02-23 Alexandre Perez-Lebel , Gaël Varoquaux , Marine Le Morvan , Julie Josse , Jean-Baptiste Poline

Decision making from data involves identifying a set of attributes that contribute to effective decision making through computational intelligence. The presence of missing values greatly influences the selection of right set of attributes…

Machine Learning · Computer Science 2013-07-23 M. Naresh Kumar

Time series classification with missing data is a prevalent issue in time series analysis, as temporal data often contain missing values in practical applications. The traditional two-stage approach, which handles imputation and…

Machine Learning · Computer Science 2024-08-13 Pengshuai Yao , Mengna Liu , Xu Cheng , Fan Shi , Huan Li , Xiufeng Liu , Shengyong Chen

Missing data represents a fundamental challenge in machine learning applications, often reducing model performance and reliability. This problem is particularly acute in fields like bioinformatics and clinical machine learning, where…

Machine Learning · Computer Science 2025-09-04 Fatemeh Azad , Zoran Bosnić , Matjaž Kukar

Missing data persists as a major barrier to data analysis across numerous applications. Recently, deep generative models have been used for imputation of missing data, motivated by their ability to capture highly non-linear and complex…

Machine Learning · Statistics 2022-10-03 Breeshey Roskams-Hieter , Jude Wells , Sara Wade

Researchers now routinely use AI or other machine learning methods to estimate latent variables of economic interest, then plug-in the estimates as covariates in a regression. We show both theoretically and empirically that naively treating…

Econometrics · Economics 2025-05-01 Laura Battaglia , Timothy Christensen , Stephen Hansen , Szymon Sacher

Multiple imputation (MI) is a method for repairing and analyzing data with missing values. MI replaces missing values with a sample of random values drawn from an imputation model. The most popular form of MI, which we call posterior draw…

Methodology · Statistics 2019-11-18 Paul T. von Hippel , Jonathan Bartlett

Tabular data is a fundamental form of data structure. The evolution of table analysis tools reflects humanity's continuous progress in data acquisition, management, and processing. The dynamic changes in table columns arise from…

Artificial Intelligence · Computer Science 2026-01-28 Xinda Chen , Zhen Xing , Hanyu Zhang , Weimin Tan , Bo Yan

We consider the problem of handling missing data with deep latent variable models (DLVMs). First, we present a simple technique to train DLVMs when the training set contains missing-at-random data. Our approach, called MIWAE, is based on…

Machine Learning · Statistics 2019-02-05 Pierre-Alexandre Mattei , Jes Frellsen

Widely used methods for analyzing missing data can be biased in small samples. To understand these biases, we evaluate in detail the situation where a small univariate normal sample, with values missing at random, is analyzed using either…

Statistics Theory · Mathematics 2017-03-27 Paul T. von Hippel

In the last couple of decades, there has been major advancements in the domain of missing data imputation. The techniques in the domain include amongst others: Expectation Maximization, Neural Networks with Evolutionary Algorithms or…

Neural and Evolutionary Computing · Computer Science 2015-12-07 Collins Leke , Tshilidzi Marwala , Satyakama Paul

Missing data imputation (MDI) is a fundamental problem in many scientific disciplines. Popular methods for MDI use global statistics computed from the entire data set (e.g., the feature-wise medians), or build predictive models operating…

Machine Learning · Computer Science 2020-06-25 Indro Spinelli , Simone Scardapane , Aurelio Uncini

When fitting a generalized linear model -- such as a linear regression, a logistic regression, or a hierarchical linear model -- analysts often wonder how to handle missing values of the dependent variable Y. If missing values have been…

Methodology · Statistics 2017-03-27 Paul T. von Hippel

Multiple imputation is a straightforward method for handling missing data in a principled fashion. This paper presents an overview of multiple imputation, including important theoretical results and their practical implications for…

Methodology · Statistics 2018-01-15 Jared S. Murray

Multiple imputation is a highly recommended technique to deal with missing data, but the application to longitudinal datasets can be done in multiple ways. When a new wave of longitudinal data arrives, we can treat the combined data of…

Methodology · Statistics 2026-05-18 X. M. Kavelaars , S. van Buuren , J. R. van Ginkel

Data for which a set of objects is described by multiple distinct feature sets (called views) is known as multi-view data. When missing values occur in multi-view data, all features in a view are likely to be missing simultaneously. This…

Machine Learning · Statistics 2024-06-21 Wouter van Loon , Marjolein Fokkema , Frank de Vos , Marisa Koini , Reinhold Schmidt , Mark de Rooij

Handling missing data remains a fundamental challenge in real-world tabular datasets, especially when data are heterogeneous with both numerical and categorical features. Existing imputation methods often fail to capture complex structural…

Machine Learning · Computer Science 2025-12-01 Youran Zhou , Mohamed Reda Bouadjenek , Sunil Aryal%

Missing values are a major challenge in most data science projects working on real data. To avoid losing valuable information, imputation methods are used to fill in missing values with estimates, allowing the preservation of samples or…

Machine Learning · Computer Science 2024-07-17 Pedro Pons-Suñer , Laura Arnal , J. Ramón Navarro-Cerdán , François Signol