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In recent years, the size of pre-trained language models (PLMs) has grown by leaps and bounds. However, efficiency issues of these large-scale PLMs limit their utilization in real-world scenarios. We present a suite of cost-effective…

The use of Large Language Models (LLMs) in hardware design has taken off in recent years, principally through its incorporation in tools that increase chip designer productivity. There has been considerable discussion about the use of LLMs…

Hardware Architecture · Computer Science 2025-05-20 Nicolas Dupuis , Ravi Nair , Shyam Ramji , Sean McClintock , Nishant Chauhan , Priyanka Nagpal , Bart Blaner , Ken Valk , Leon Stok , Ruchir Puri

The rapid development of large language models (LLM) has greatly enhanced everyday applications. While many FPGA-based accelerators, with flexibility for fine-grained data control, exhibit superior speed and energy efficiency compared to…

Hardware Architecture · Computer Science 2026-03-24 Zifan He , Shengyu Ye , Rui Ma , Yang Wang , Jason Cong

As large language models (LLMs) scale in size and adoption, their computational and environmental costs continue to rise. Prior benchmarking efforts have primarily focused on latency reduction in idealized settings, often overlooking the…

Computation and Language · Computer Science 2025-04-25 Jared Fernandez , Clara Na , Vashisth Tiwari , Yonatan Bisk , Sasha Luccioni , Emma Strubell

The impact of Transformer-based language models has been unprecedented in Natural Language Processing (NLP). The success of such models has also led to their adoption in other fields including bioinformatics. Taking this into account, this…

Machine Learning · Computer Science 2025-07-21 Nimisha Ghosh , Daniele Santoni , Debaleena Nawn , Eleonora Ottaviani , Giovanni Felici

Large Language Models (LLMs) play a central role in modern artificial intelligence, yet their development has been primarily focused on English, resulting in limited support for other languages. We present PLLuM (Polish Large Language…

Computation and Language · Computer Science 2025-11-07 Jan Kocoń , Maciej Piasecki , Arkadiusz Janz , Teddy Ferdinan , Łukasz Radliński , Bartłomiej Koptyra , Marcin Oleksy , Stanisław Woźniak , Paweł Walkowiak , Konrad Wojtasik , Julia Moska , Tomasz Naskręt , Bartosz Walkowiak , Mateusz Gniewkowski , Kamil Szyc , Dawid Motyka , Dawid Banach , Jonatan Dalasiński , Ewa Rudnicka , Bartłomiej Alberski , Tomasz Walkowiak , Aleksander Szczęsny , Maciej Markiewicz , Tomasz Bernaś , Hubert Mazur , Kamil Żyta , Mateusz Tykierko , Grzegorz Chodak , Tomasz Kajdanowicz , Przemysław Kazienko , Agnieszka Karlińska , Karolina Seweryn , Anna Kołos , Maciej Chrabąszcz , Katarzyna Lorenc , Aleksandra Krasnodębska , Artur Wilczek , Katarzyna Dziewulska , Paula Betscher , Zofia Cieślińska , Katarzyna Kowol , Daria Mikoś , Maciej Trzciński , Dawid Krutul , Marek Kozłowski , Sławomir Dadas , Rafał Poświata , Michał Perełkiewicz , Małgorzata Grębowiec , Maciej Kazuła , Marcin Białas , Roman Roszko , Danuta Roszko , Jurgita Vaičenonienė , Andrius Utka , Paweł Levchuk , Paweł Kowalski , Irena Prawdzic-Jankowska , Maciej Ogrodniczuk , Monika Borys , Anna Bulińska , Wiktoria Gumienna , Witold Kieraś , Dorota Komosińska , Katarzyna Krasnowska-Kieraś , Łukasz Kobyliński , Martyna Lewandowska , Marek Łaziński , Mikołaj Łątkowski , Dawid Mastalerz , Beata Milewicz , Agnieszka Anna Mykowiecka , Angelika Peljak-Łapińska , Sandra Penno , Zuzanna Przybysz , Michał Rudolf , Piotr Rybak , Karolina Saputa , Aleksandra Tomaszewska , Aleksander Wawer , Marcin Woliński , Joanna Wołoszyn , Alina Wróblewska , Bartosz Żuk , Filip Żarnecki , Konrad Kaczyński , Anna Cichosz , Zuzanna Deckert , Monika Garnys , Izabela Grabarczyk , Wojciech Janowski , Sylwia Karasińska , Aleksandra Kujawiak , Piotr Misztela , Maria Szymańska , Karolina Walkusz , Igor Siek , Jakub Kwiatkowski , Piotr Pęzik

Recent advances in NLP are brought by a range of large-scale pretrained language models (PLMs). These PLMs have brought significant performance gains for a range of NLP tasks, circumventing the need to customize complex designs for specific…

Computation and Language · Computer Science 2022-11-08 Xu Guo , Han Yu

In this study, we expand upon the FLIP benchmark-designed for evaluating protein fitness prediction models in small, specialized prediction tasks-by assessing the performance of state-of-the-art large protein language models, including…

Machine Learning · Computer Science 2025-01-31 Manuel F. Mollon , Joaquin Gonzalez-Rodriguez , Alicia Lozano-Diez , Daniel Ramos , Doroteo T. Toledano

Large language models (LLMs) have garnered considerable attention for their proficiency in tackling intricate tasks, particularly leveraging their capacities for zero-shot and in-context learning. However, their utility has been…

Biomolecules · Quantitative Biology 2024-05-14 Yiqing Shen , Outongyi Lv , Houying Zhu , Yu Guang Wang

Recent breakthroughs in Large-scale language models (LLMs) have demonstrated impressive performance on various tasks. The immense sizes of LLMs have led to very high resource demand and cost for running the models. Though the models are…

Machine Learning · Computer Science 2024-03-05 Juntao Zhao , Borui Wan , Yanghua Peng , Haibin Lin , Chuan Wu

Pretrained language models (PLMs) are trained on massive corpora, but often need to specialize to specific domains. A parameter-efficient adaptation method suggests training an adapter for each domain on the task of language modeling. This…

Computation and Language · Computer Science 2023-03-29 Alexandra Chronopoulou , Matthew E. Peters , Alexander Fraser , Jesse Dodge

Computational biology and bioinformatics provide vast data gold-mines from protein sequences, ideal for Language Models taken from NLP. These LMs reach for new prediction frontiers at low inference costs. Here, we trained two…

Sparse large language models (LLMs) with Mixture of Experts (MoE) and close to a trillion parameters are dominating the realm of most capable language models. However, the massive model scale poses significant challenges for the underlying…

Designing proteins with desired functions or properties represents a core goal in synthetic biology and drug discovery. Recent advances in protein language models (PLMs) have enabled the generation of highly designable protein sequences,…

Machine Learning · Computer Science 2026-05-12 Yulin Zhang , He Cao , Zihao Jiang , Chenyi Zi , Zhipeng Zhou , Zijing Liu , Yu Li , Jia Li , Ziqi Gao

Computational protein design is experiencing a transformation driven by AI/ML. However, the range of potential protein sequences and structures is astronomically vast, even for moderately sized proteins. Hence, achieving convergence between…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-09 Aymen Alsaadi , Jonathan Ash , Mikhail Titov , Matteo Turilli , Andre Merzky , Shantenu Jha , Sagar Khare

Large Language Models (LLMs) offer state-of-the-art performance in natural language understanding and generation tasks. However, the deployment of leading commercial models for specialized tasks, such as e-commerce, is often hindered by…

Artificial Intelligence · Computer Science 2025-10-28 Josip Tomo Licardo , Nikola Tankovic

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

Modern large language foundation models (LLM) have now entered the daily lives of millions of users. We ask a natural question whether it is possible to customize LLM for every user or every task. From system and industrial economy…

Machine Learning · Computer Science 2025-04-11 Jianqiao Wangni

While protein language models (PLMs) are one of the most promising avenues of research for future de novo protein design, the way in which they transform sequences to hidden representations, as well as the information encoded in such…

Machine Learning · Computer Science 2026-05-29 Kosio Beshkov , Anders Malthe-Sørenssen

Fine-tuning of Large Language Models (LLMs) for downstream tasks, performed on domain-specific data has shown significant promise. However, commercial use of such LLMs is limited by the high computational cost required for their deployment…

Computation and Language · Computer Science 2025-03-06 Boris Nazarov , Darya Frolova , Yackov Lubarsky , Alexei Gaissinski , Pavel Kisilev
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