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In this paper, we suggested eleven protein targets to be used as possible vaccines against Plasmodium falciparum causative agent of almost two to three million deaths per year. A comprehensive analysis of protein target have been selected…

Genomics · Quantitative Biology 2010-09-30 Raul Isea

Malaria is mosquito-borne blood disease caused by parasites of the genus Plasmodium. Conventional diagnostic tool for malaria is the examination of stained blood cell of patient in microscope. The blood to be tested is placed in a slide and…

Image and Video Processing · Electrical Eng. & Systems 2018-03-30 Suman Kunwar

The organization and mining of malaria genomic and post-genomic data is highly motivated by the necessity to predict and characterize new biological targets and new drugs. Biological targets are sought in a biological space designed from…

Quantitative Methods · Quantitative Biology 2016-08-16 L. -M. Birkholtz , O. Bastien , G. Wells , D. Grando , F. Joubert , V. Kasam , M. Zimmermann , P. Ortet , N. Jacq , S. Roy , M. Hoffmann-Apitius , V. Breton , A. I. Louw , E. Maréchal

To have the greatest impact, public health initiatives must be made using evidence-based decision-making. Machine learning Algorithms are created to gather, store, process, and analyse data to provide knowledge and guide decisions. A…

Machine Learning · Computer Science 2022-09-28 Imen Jdey , Ghazala Hcini , Hela Ltifi

Accurate detection of Plasmodium falciparum in Giemsa-stained blood smears is an essential component of reliable malaria diagnosis, especially in developing countries. Deep learning-based object detection methods have demonstrated strong…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Frauke Wilm , Luis Carlos Rivera Monroy , Mathias Öttl , Lukas Mürdter , Leonid Mill , Andreas Maier

Malaria is a serious disease caused by the Plasmodium parasite that transmitted through the bite of a female Anopheles mosquito and invades human erythrocytes. Malaria must be recognized precisely in order to treat the patient in time and…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Julisa Bana Abraham

Background: Phage therapy shows promise for treating antibiotic-resistant Klebsiella infections. Identifying phage depolymerases that target Klebsiella capsular polysaccharides is crucial, as these capsules contribute to biofilm formation…

Genomics · Quantitative Biology 2025-01-29 George Wright , Slawomir Michniewski , Eleanor Jameson , Fayyaz ul Amir Afsar Minhas

Malaria microscopy, microscopic examination of stained blood slides to detect parasite Plasmodium, is considered to be a gold-standard for detecting life-threatening disease malaria. Detecting the plasmodium parasite requires a skilled…

Image and Video Processing · Electrical Eng. & Systems 2021-02-18 Qazi Ammar Arshad , Mohsen Ali , Saeed-ul Hassan , Chen Chen , Ayisha Imran , Ghulam Rasul , Waqas Sultani

Due to the rise in antimicrobial resistance, identifying novel compounds with antibiotic potential is crucial for combatting this global health issue. However, traditional drug development methods are costly and inefficient. Recognizing the…

Biomolecules · Quantitative Biology 2025-02-18 Gen Zhou , Sugitha Janarthanan , Yutong Lu , Pingzhao Hu

Improving the efficiency of malaria diagnosis is one of the main goals of current malaria research. We have recently developed a magneto-optical (MO) method which allows high-sensitivity detection of malaria pigment (hemozoin) crystals via…

Malaria remains a prevalent health concern in regions with tropical and subtropical climates. The cause of malaria is the Plasmodium parasite, which is transmitted through the bites of infected female Anopheles mosquitoes. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Md. Ismiel Hossen Abir , Awolad Hossain

Protein function prediction is a pivotal task in drug discovery, significantly impacting the development of effective and safe therapeutics. Traditional machine learning models often struggle with the complexity and variability inherent in…

Machine Learning · Computer Science 2024-09-24 Bohao Xu , Yingzhou Lu , Yoshitaka Inoue , Namkyeong Lee , Tianfan Fu , Jintai Chen

A wide range of methods currently exist for testing the presence of malaria, each with its own advantages and disadvantages. New technologies are urgently needed to develop more effective diagnosis tools to fight and eradicate malaria.…

Medical Physics · Physics 2025-08-26 A. S. Kiyumbi , M. S. Tame

Malaria remains a major health threat in low-resource regions and rapid diagnostic tests often lack the sensitivity required for early detection. To address this and help establish more sensitive testing devices, we develop a predictive…

Optics · Physics 2026-01-15 A. S. Kiyumbi , M. S. Tame

Automated malaria diagnosis is a difficult but high-value target for machine learning (ML), and effective algorithms could save many thousands of children's lives. However, current ML efforts largely neglect crucial use case constraints and…

Machine Learning · Computer Science 2023-07-06 Charles B. Delahunt , Noni Gachuhi , Matthew P. Horning

The analysis and counting of blood cells in a microscope image can provide useful information concerning to the health of a person. In particular, morphological analysis of red blood cells deformations can effectively detect important…

Computers and Society · Computer Science 2013-12-05 Pramit Ghosh , Debotosh Bhattacharjee , Mita Nasipuri , Dipak Kumar Basu

Falciparum malaria is a major parasitic disease causing widespread morbidity and mortality globally. Artemisinin derivatives---the most effective and widely-used antimalarials that have helped reduce the burden of malaria by 60% in some…

In an era of escalating cyber threats, malware poses significant risks to individuals and organizations, potentially leading to data breaches, system failures, and substantial financial losses. This study addresses the urgent need for…

Cryptography and Security · Computer Science 2025-01-28 Marzieh Esnaashari , Nima Moradi

A timely immunization can be effective against certain diseases and can save thousands of lives. However, for some diseases it has been difficult, so far, to develop an efficient vaccine. Malaria, a tropical disease caused by a parasite of…

Genomics · Quantitative Biology 2016-11-08 Raul Isea , Rafael Mayo-Garcia , Silvia Restrepo
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