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As quantum machine-learning architectures mature, a central challenge is no longer their construction, but identifying the regimes in which they offer practical advantages over classical approaches. In this work, we introduce a framework…

Machine Learning · Computer Science 2026-01-21 Brandon B. Le , D. Keller

While quantum architectures are still under development, when available, they will only be able to process quantum data when machine learning algorithms can only process numerical data. Therefore, in the issues of classification or…

Machine Learning · Computer Science 2025-12-16 Rafal Potempa , Sebastian Porebski

In this paper, we propose a new methodology to design quantum hybrid diffusion models, derived from classical U-Nets with ResNet and Attention layers. Specifically, we propose two possible different hybridization schemes combining quantum…

The accurate screening of candidate drug ligands against target proteins through computational approaches is of prime interest to drug development efforts. Such virtual screening depends in part on methods to predict the binding affinity…

Machine Learning · Computer Science 2024-10-22 Ho-Joon Lee , Prashant S. Emani , Mark B. Gerstein

For the last few decades, classical machine learning has allowed us to improve the lives of many through automation, natural language processing, predictive analytics and much more. However, a major concern is the fact that we're fast…

Quantum Physics · Physics 2021-06-22 Arhum Ishtiaq , Sara Mahmood

Image classification is a fundamental computer vision problem, and neural networks offer efficient solutions. With advancing quantum technology, quantum neural networks have gained attention. However, they work only for low-dimensional data…

Quantum Physics · Physics 2023-08-31 Mingrui Shi , Haozhen Situ , Cai Zhang

Financial services is a prospect industry where unlocked near-term quantum utility could yield profitable potential, and, in particular, quantum machine learning algorithms could potentially benefit businesses by improving the quality of…

Classification is particularly relevant to Information Retrieval, as it is used in various subtasks of the search pipeline. In this work, we propose a quantum convolutional neural network (QCNN) for multi-class classification of classical…

Quantum Physics · Physics 2024-04-22 Marco Mordacci , Davide Ferrari , Michele Amoretti

Quantum computing (QC) has gained popularity due to its unique capabilities that are quite different from that of classical computers in terms of speed and methods of operations. This paper proposes hybrid models and methods that…

Quantum Physics · Physics 2019-11-12 Akshay Ajagekar , Travis Humble , Fengqi You

Quantum machine learning is one of the fields where quantum computers are expected to bring advantages over classical methods. However, the limited size of current computers restricts the exploitation of the full potential of quantum…

Quantum Physics · Physics 2025-11-10 Juan C. Boschero , Ward van der Schoot , Niels M. P. Neumann

Quantum computing provides computational advantages in various domains. To benefit from these advantages complex hybrid quantum applications must be built, which comprise both quantum and classical programs. Engineering these applications…

Medical images are characterized by intricate and complex features, requiring interpretation by physicians with medical knowledge and experience. Classical neural networks can reduce the workload of physicians, but can only handle these…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Yangyang Li , Zhengya Qia , Yuelin Lia , Haorui Yanga , Ronghua Shanga , Licheng Jiaoa

The advent of hybrid computing platforms consisting of quantum processing units integrated with conventional high-performance computing brings new opportunities for algorithm design. By strategically offloading select portions of the…

Quantum machine learning deals with leveraging quantum theory with classic machine learning algorithms. Current research efforts study the advantages of using quantum mechanics or quantum information theory to accelerate learning time or…

Quantum Physics · Physics 2025-09-03 Javier Orduz , Pablo Rivas , Erich Baker

Quantum machine learning (QML) investigates how quantum phenomena can be exploited in order to learn data in an alternative way, \textit{e.g.} by means of a quantum computer. While recent results evidence that QML models can potentially…

Quantum Physics · Physics 2024-07-10 Y. Cordero , S. Biswas , F. Vilariño , M. Bilkis

We present a quantum-in-quantum embedding strategy coupled to machine learning potentials to improve on the accuracy of quantum-classical hybrid models for the description of large molecules. In such hybrid models, relevant structural…

Quantum machine learning has emerged as a promising approach to improve feature extraction and classification tasks in high-dimensional data domains such as medical imaging. In this work, we present a hybrid Quantum-Classical Convolutional…

Quantum Physics · Physics 2026-05-12 Ece Yurtseven

Machine learning is a promising application of quantum computing, but challenges remain as near-term devices will have a limited number of physical qubits and high error rates. Motivated by the usefulness of tensor networks for machine…

Quantum Physics · Physics 2019-02-07 William Huggins , Piyush Patel , K. Birgitta Whaley , E. Miles Stoudenmire

Effective and accurate diagnosis of diseases such as cancer, diabetes, and heart failure is crucial for timely medical intervention and improving patient survival rates. Machine learning has revolutionized diagnostic methods in recent years…

Machine Learning · Computer Science 2025-12-02 Antonio Tudisco , Deborah Volpe , Giovanna Turvani

Deep neural networks remain highly vulnerable to adversarial perturbations, limiting their reliability in security- and safety-critical applications. To address this challenge, we introduce QShield, a modular hybrid quantum-classical neural…

Cryptography and Security · Computer Science 2026-04-14 Navid Azimi , Aditya Prakash , Yao Wang , Li Xiong
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