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The diffusion of molecules (penetrants) of variable size, shape, and chemistry through dense crosslinked polymer networks is a fundamental scientific problem that is broadly relevant in materials, polymer, physical and biological chemistry.…

We generalize and apply a microscopic force-level statistical mechanical theory of the activated dynamics of dilute spherical penetrants in glass-forming liquids to study the influence of permanent crosslinking in polymer networks on the…

Soft Condensed Matter · Physics 2023-06-09 Baicheng Mei , Tsai-Wei Lin , Charles E. Sing , Kenneth S. Schweizer

Diffusive transport of small molecules within the internal structures of biological and synthetic material systems is complex because the crowded environment presents chemical and physical barriers to mobility. We explored this mobility…

Soft Condensed Matter · Physics 2020-09-29 Rajarshi Guha , Subhadip Ghosh , Darrell Velegol , Peter J. Butler , Ayusman Sen , Jennifer L. Ross

Phase separation within polymer networks plays a central role in shaping the structure and mechanics of both synthetic materials and living cells, including the formation of biomolecular condensates within cytoskeletal networks. Previous…

Soft Condensed Matter · Physics 2025-12-01 Takahiro Yokoyama , Yicheng Qiang , David Zwicker , Arash Nikoubashman

Fundamental understanding of the effect of microscopic parameters on the dynamics of probe particles in different complex environments has wide implications. Examples include diffusion of proteins in the biological hydrogels, porous media,…

Soft Condensed Matter · Physics 2019-09-11 Praveen Kumar , Ligesh Theeyancheri , Subhasish Chaki , Rajarshi Chakrabarti

Mesh-like structures, such as mucus gel or cytoskeleton networks, are ubiquitous in biological systems. These intricate structures are composed of cross-linked, semi-flexible bio-filaments, crucial to numerous biological processes. In many…

Soft Condensed Matter · Physics 2024-01-10 Yeongjin Kim , Won Kyu Kim , Jae-Hyung Jeon

Living cells are characterized by the micrometric confinement of various macromolecules at high concentrations. Using droplets containing binary polymer blends as artificial cells, we previously showed that cell-sized confinement causes…

Transport of tracer particles through mesh-like environments such as biological hydrogels and polymer matrices is ubiquitous in nature. These tracers could be passive, such as colloids or active (self-propelled), such as synthetic…

Soft Condensed Matter · Physics 2022-12-08 Praveen Kumar , Rajarshi Chakrabarti

We review recent results from computer simulation studies of polymer glasses, from chain dynamics around the glass transition temperature Tg to the mechanical behaviour below Tg. These results clearly show that modern computer simulations…

Materials Science · Physics 2010-09-29 Jean-Louis Barrat , Joerg Baschnagel , Alexei Lyulin

The formation of (bio)molecular condensates via liquid-liquid phase separation in cells has received increasing attention, as these coacervates play important functional and regulatory roles within biological systems. However, the majority…

Soft Condensed Matter · Physics 2022-11-24 Arash Nikoubashman , Miho Yanagisawa

For a wide range of modern soft functional materials the selective transport of sub-nanometer-sized molecules (`penetrants') through a stimuli-responsive polymeric membrane is key to the desired function. In this study, we investigate the…

Soft Condensed Matter · Physics 2018-08-28 Matej Kanduc , Won Kyu Kim , Rafael Roa , Joachim Dzubiella

In the cell, protein complexes form relying on specific interactions between their monomers. Excluded volume effects due to molecular crowding would lead to correlations between molecules even without specific interactions. What is the…

Soft Condensed Matter · Physics 2015-05-13 Wei Wang , Wei-Xin Xu , Y. Levy , E. Trizac , P. G. Wolynes

We present molecular dynamics simulations of a simple model for polymer melts with intramolecular barriers. We investigate structural relaxation as a function of the barrier strength. Dynamic correlators can be consistently analyzed within…

Soft Condensed Matter · Physics 2009-11-13 Marco Bernabei , Angel J. Moreno , Juan Colmenero

Free surfaces in glassy polymer films are known to induce surface mobile layers with enhanced dynamics. Using molecular dynamics simulations of a bead-spring model, we study a wide variety of layer-resolved structural and dynamical…

Soft Condensed Matter · Physics 2018-11-14 Chi-Hang Lam

Using molecular dynamics simulation, we investigate the effect of confinement on a system that comprises several stiff segmented polymer chains where each chain has similar segments, but length and stiffness of the segments vary among the…

Soft Condensed Matter · Physics 2015-07-14 Arash Azari , Kristian K. Müller-Nedebock

Polymer-related materials exhibit rich glassy behaviors at different length scales due to their various molecular structures and topological constraints. Recent studies have identified transient interpenetration of the long-chain rings…

Soft Condensed Matter · Physics 2024-07-08 Jian Li , Bokai Zhang , Yushan Li

We present computer simulations of a simple bead-spring model for polymer melts with intramolecular barriers. By systematically tuning the strength of the barriers, we investigate their role on the glass transition. Dynamic observables are…

Soft Condensed Matter · Physics 2015-05-14 Marco Bernabei , Angel J. Moreno , Juan Colmenero

An important indicator of membrane performance are free volume elements (FVEs): microporous void spaces created by the inefficient packing of bulky groups along the polymer chain. FVEs tend to degrade over time as polymer chains reorganize…

Soft Condensed Matter · Physics 2023-06-21 Mohammed Al Otmi , Frank Willmore , Janani Sampath

Diffusion of long ring polymers in a melt is much slower than the reorganization of their internal structures. While direct evidences for entanglements have not been observed in the long ring polymers unlike linear polymer melts, threading…

Soft Condensed Matter · Physics 2015-10-21 Eunsang Lee , Soree Kim , YounJoon Jung

We study the permeability and selectivity (`permselectivity') of model membranes made of polydisperse polymer networks for molecular penetrant transport, using coarse-grained, implicit-solvent computer simulations. The permeability…

Soft Condensed Matter · Physics 2020-09-30 Won Kyu Kim , Richard Chudoba , Sebastian Milster , Rafael Roa , Matej Kanduc , Joachim Dzubiella
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