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Hyperspectral imaging (HSI) is an advanced sensing modality that simultaneously captures spatial and spectral information, enabling non-invasive, label-free analysis of material, chemical, and biological properties. This Primer presents a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Danfeng Hong , Chenyu Li , Naoto Yokoya , Bing Zhang , Xiuping Jia , Antonio Plaza , Paolo Gamba , Jon Atli Benediktsson , Jocelyn Chanussot

Hyperspectral Imaging (HSI) for fluorescence-guided brain tumor resection enables visualization of differences between tissues that are not distinguishable to humans. This augmentation can maximize brain tumor resection, improving patient…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 David Black , Jaidev Gill , Andrew Xie , Benoit Liquet , Antonio Di leva , Walter Stummer , Eric Suero Molina

In this paper, we propose a methodology for extracting molecular tumor biomarkers from hyperspectral imaging (HSI), an emerging technology for intraoperative tissue assessment. To achieve this, we employ spectral unmixing, allowing to…

Hyperspectral imaging (HSI) holds significant potential for transforming the field of computational pathology. However, there is currently a shortage of pixel-wise annotated HSI data necessary for training deep learning (DL) models.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-12 Ivica Kopriva , Dario Sitnik , Laura-Isabelle Dion-Bertrand , Marija Milković Periša , Mirko Hadžija , Marijana Popović Hadžija

Surgery for gliomas (intrinsic brain tumors), especially when low-grade, is challenging due to the infiltrative nature of the lesion. Currently, no real-time, intra-operative, label-free and wide-field tool is available to assist and guide…

Hyperspectral imaging (HSI) is an advanced medical imaging modality that captures optical data across a broad spectral range, providing novel insights into the biochemical composition of tissues. HSI may enable precise differentiation…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Zhonghao Wang , Junwen Wang , Charlie Budd , Oscar MacCormac , Jonathan Shapey , Tom Vercauteren

Hyperspectral imaging (HSI) unlocks the huge potential to a wide variety of applications relied on high-precision pathology image segmentation, such as computational pathology and precision medicine. Since hyperspectral pathology images…

Image and Video Processing · Electrical Eng. & Systems 2021-03-08 Boxiang Yun , Yan Wang , Jieneng Chen , Huiyu Wang , Wei Shen , Qingli Li

Hyperspectral imagery (HSI) is an established technique with an array of applications, but its use is limited due to both practical and technical issues associated with spectral devices. The goal of the ICASSP 2024 'Hyper-Skin' Challenge is…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Wojciech Czaja , Jeremiah Emidih , Brandon Kolstoe , Richard G. Spencer

Hyperspectral imaging (HSI) is an emerging modality in health-care applications for disease diagnosis, tissue assessment and image-guided surgery. Tissue reflectances captured by a HSI camera encode physiological properties including…

Medical Physics · Physics 2019-04-08 Anant S. Vemuri , Sebastian Wirkert , Lena Maier-Hein

Hyperspectral imaging (HSI) has a wide range of applications from environmental monitoring to biotechnology. Current snapshot HSI techniques all require a trade-off between spatial and spectral resolution and are thus unable to achieve high…

Optics · Physics 2023-01-11 Yingwen Zhang , Duncan England , Benjamin Sussman

Hyperspectral/multispectral imaging (HSI/MSI) contains rich information clinical applications, such as 1) narrow band imaging for vascular visualisation; 2) oxygen saturation for intraoperative perfusion monitoring and clinical decision…

Computer Vision and Pattern Recognition · Computer Science 2017-07-13 Jianyu Lin , Neil T. Clancy , Daniel S. Elson

Visual discrimination of clinical tissue types remains challenging, with traditional RGB imaging providing limited contrast for such tasks. Hyperspectral imaging (HSI) is a promising technology providing rich spectral information that can…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Luis C. Garcia-Peraza-Herrera , Conor Horgan , Sebastien Ourselin , Michael Ebner , Tom Vercauteren

Tissue surface shape and reflectance spectra provide rich intra-operative information useful in surgical guidance. We propose a hybrid system which displays an endoscopic image with a fast joint inspection of tissue surface shape using…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Jianyu Lin , Neil T. Clancy , Xueqing Sun , Ji Qi , Mirek Janatka , Danail Stoyanov , Daniel S. Elson

Surgery for brain cancer is a major problem in neurosurgery. The diffuse infiltration into the surrounding normal brain by these tumors makes their accurate identification by the naked eye difficult. Since surgery is the common treatment…

Hadamard Transform Spectral Imaging (HTSI) is a multiplexing technique used to recover spectra via encoding with multi-slit masks, and is particularly useful in low photon flux applications where signal-independent noise is the dominant…

Instrumentation and Methods for Astrophysics · Physics 2025-10-24 John Nijim , Zoran Ninkov , Dmitry Vorobiev , Kevin Kearney

Hyperspectral Imaging (HSI) combines microscopy and spectroscopy to assess the spatial distribution of spectroscopically active compounds in objects, and has diverse applications in food quality control, pharmaceutical processes, and waste…

Image and Video Processing · Electrical Eng. & Systems 2023-08-30 Mahdiyeh Ghaffari , Mickey C. J. Lukkien , Nematollah Omidikia , Gerjen H. Tinnevelt , Marcel C. P. van Eijk , Jeroen J. Jansen

Through spectral unmixing, hyperspectral imaging (HSI) in fluorescence-guided brain tumor surgery has enabled detection and classification of tumor regions invisible to the human eye. Prior unmixing work has focused on determining a minimal…

Image and Video Processing · Electrical Eng. & Systems 2024-02-01 David Black , Benoit Liquet , Sadahiro Kaneko , Antonio Di leva , Walter Stummer , Eric Suero Molina

Coded aperture snapshot spectral imaging (CASSI) is a promising technique to capture the three-dimensional hyperspectral image (HSI) using a single coded two-dimensional (2D) measurement, in which algorithms are used to perform the inverse…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Wei He , Naoto Yokoya , Xin Yuan

Hyperspectral Imaging (HSI) serves as a non-destructive spatial spectroscopy technique with a multitude of potential applications. However, a recurring challenge lies in the limited size of the target datasets, impeding exhaustive…

Computer Vision and Pattern Recognition · Computer Science 2023-09-21 Hannah Frank , Leon Amadeus Varga , Andreas Zell

Functional Spectral Imaging (FSI) models image formation as the recovery of tissue surrogates such as density and stiffness from spectral perturbations of a self-adjoint elliptic operator. Rather than relying on reflectivity or relaxation…

Medical Physics · Physics 2025-10-21 Cesar Mello Fernando Medina da Cunha
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