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Most tumor grading systems for human as for veterinary histopathology are based upon the absolute count of mitotic figures in a certain reference area of a histology slide. Since time for prognostication is limited in a diagnostic setting,…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Marc Aubreville , Christof A. Bertram , Robert Klopfleisch , Andreas Maier

The growing demand for accurate and equitable AI models in digital dermatology faces a significant challenge: the lack of diverse, high-quality labeled data. In this work, we investigate the potential of domain-specific foundation models…

Deep learning models usually suffer from domain shift issues, where models trained on one source domain do not generalize well to other unseen domains. In this work, we investigate the single-source domain generalization problem: training a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-24 Cheng Ouyang , Chen Chen , Surui Li , Zeju Li , Chen Qin , Wenjia Bai , Daniel Rueckert

Computer assisted diagnosis in digital pathology is becoming ubiquitous as it can provide more efficient and objective healthcare diagnostics. Recent advances have shown that the convolutional Neural Network (CNN) architectures, a…

Image and Video Processing · Electrical Eng. & Systems 2022-01-05 Sruthi Krishna , Suganthi S. S , Shivsubramani Krishnamoorthy , Arnav Bhavsar

We propose a unified cross-domain transfer learning framework that leverages knowledge from multiple heterogeneous medical imaging datasets to improve performance across segmentation, classification, and object detection tasks. Our approach…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Ceausescu Ciprian-Mihai , Anghelina Ion-Marian , Alexe Dumitru-Bogdan

This manuscript presents an image segmentation algorithm developed for the Cross-Organ and Cross-Scanner Adenocarcinoma Segmentation (COSAS 2024) challenge. We adopted an organ-stratified and scanner-stratified approach to train multiple…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Huang Jiayan , Ji Zheng , Kuang Jinbo , Xu Shuoyu

Computational pathology (CPath) has shown great potential in mining actionable insights from Whole Slide Images (WSIs). Deep Learning (DL) has been at the center of modern CPath, and while it delivers unprecedented performance, it is also…

Quantitative Methods · Quantitative Biology 2025-07-31 Gianluca Carloni , Biagio Brattoli , Seongho Keum , Jongchan Park , Taebum Lee , Chang Ho Ahn , Sergio Pereira

Variability in staining protocols, such as different slide preparation techniques, chemicals, and scanner configurations, can result in a diverse set of whole slide images (WSIs). This distribution shift can negatively impact the…

Image and Video Processing · Electrical Eng. & Systems 2023-04-25 Kudaibergen Abutalip , Numan Saeed , Mustaqeem Khan , Abdulmotaleb El Saddik

Background: Histopathology is an important modality for the diagnosis and management of many diseases in modern healthcare, and plays a critical role in cancer care. Pathology samples can be large and require multi-site sampling, leading to…

We provide in this paper a comprehensive comparison of various transfer learning strategies and deep learning architectures for computer-aided classification of adult-type diffuse gliomas. We evaluate the generalizability of out-of-domain…

We primarily focus on the field of multi-scenario recommendation, which poses a significant challenge in effectively leveraging data from different scenarios to enhance predictions in scenarios with limited data. Current mainstream efforts…

Information Retrieval · Computer Science 2024-04-16 Jiachen Zhu , Yichao Wang , Jianghao Lin , Jiarui Qin , Ruiming Tang , Weinan Zhang , Yong Yu

Digitized Histological diagnosis is in increasing demand. However, color variations due to various factors are imposing obstacles to the diagnosis process. The problem of stain color variations is a well-defined problem with many proposed…

Computer Vision and Pattern Recognition · Computer Science 2018-04-06 M Tarek Shaban , Christoph Baur , Nassir Navab , Shadi Albarqouni

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Elhoucine Elfatimi , Pratik Shah

The appearance of histopathology images depends on tissue type, staining and digitization procedure. These vary from source to source and are the potential causes for domain-shift problems. Owing to this problem, despite the great success…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Trinh Thi Le Vuong , Quoc Dang Vu , Mostafa Jahanifar , Simon Graham , Jin Tae Kwak , Nasir Rajpoot

Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Volodymyr Sydorskyi , Igor Krashenyi , Oleksii Yakubenko

Despite the widespread use of deep learning methods for semantic segmentation of images that are acquired from a single source, clinicians often use multi-domain data for a detailed analysis. For instance, CT and MRI have advantages over…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Bora Baydar , Savas Ozkan , A. Emre Kavur , N. Sinem Gezer , M. Alper Selver , Gozde Bozdagi Akar

In this paper, we address the dataset scarcity issue with the hyperspectral image classification. As only a few thousands of pixels are available for training, it is difficult to effectively learn high-capacity Convolutional Neural Networks…

Computer Vision and Pattern Recognition · Computer Science 2018-05-04 Hyungtae Lee , Sungmin Eum , Heesung Kwon

Skin cancer is among the most common cancer types. Dermoscopic image analysis improves the diagnostic accuracy for detection of malignant melanoma and other pigmented skin lesions when compared to unaided visual inspection. Hence,…

Computer Vision and Pattern Recognition · Computer Science 2020-06-29 Amirreza Mahbod , Gerald Schaefer , Chunliang Wang , Rupert Ecker , Georg Dorffner , Isabella Ellinger

Machine learning models for medical image analysis often suffer from poor performance on important subsets of a population that are not identified during training or testing. For example, overall performance of a cancer detection model may…

Machine Learning · Computer Science 2019-11-18 Luke Oakden-Rayner , Jared Dunnmon , Gustavo Carneiro , Christopher Ré

Many current neural networks for medical imaging generalise poorly to data unseen during training. Such behaviour can be caused by networks overfitting easy-to-learn, or statistically dominant, features while disregarding other potentially…

Image and Video Processing · Electrical Eng. & Systems 2022-12-05 Joona Pohjonen , Carolin Stürenberg , Antti Rannikko , Tuomas Mirtti , Esa Pitkänen
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