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Multi-class cell segmentation in high-resolution Giga-pixel whole slide images (WSI) is critical for various clinical applications. Training such an AI model typically requires labor-intensive pixel-wise manual annotation from experienced…

Segmentation is one of the most important tasks in the medical imaging pipeline as it influences a number of image-based decisions. To be effective, fully supervised segmentation approaches require large amounts of manually annotated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Tyler Ward , Aaron Moseley , Abdullah-Al-Zubaer Imran

Image classification systems recently made a giant leap with the advancement of deep neural networks. However, these systems require an excessive amount of labeled data to be adequately trained. Gathering a correctly annotated dataset is…

Machine Learning · Computer Science 2021-01-19 Görkem Algan , Ilkay Ulusoy

Weakly Supervised Semantic Segmentation (WSSS) is a challenging task aiming to learn the segmentation labels from class-level labels. In the literature, exploiting the information obtained from Class Activation Maps (CAMs) is widely used…

Computer Vision and Pattern Recognition · Computer Science 2022-11-24 Cenk Bircanoglu , Nafiz Arica

Can we automatically group images into semantically meaningful clusters when ground-truth annotations are absent? The task of unsupervised image classification remains an important, and open challenge in computer vision. Several recent…

Computer Vision and Pattern Recognition · Computer Science 2020-07-06 Wouter Van Gansbeke , Simon Vandenhende , Stamatios Georgoulis , Marc Proesmans , Luc Van Gool

Training high-quality instance segmentation models requires an abundance of labeled images with instance masks and classifications, which is often expensive to procure. Active learning addresses this challenge by striving for optimum…

Computer Vision and Pattern Recognition · Computer Science 2023-09-29 Ke Yu , Stephen Albro , Giulia DeSalvo , Suraj Kothawade , Abdullah Rashwan , Sasan Tavakkol , Kayhan Batmanghelich , Xiaoqi Yin

Most state-of-the-art instance segmentation methods have to be trained on densely annotated images. While difficult in general, this requirement is especially daunting for biomedical images, where domain expertise is often required for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Adrian Wolny , Qin Yu , Constantin Pape , Anna Kreshuk

Large annotated datasets are vital for training segmentation models, but pixel-level labeling is time-consuming, error-prone, and often requires scarce expert annotators, especially in medical imaging. In contrast, coarse annotations are…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Le Zhang , Fuping Wu , Arun Thirunavukarasu , Kevin Bronik , Thomas Nichols , Bartlomiej W. Papiez

3D medical image segmentation is a challenging task with crucial implications for disease diagnosis and treatment planning. Recent advances in deep learning have significantly enhanced fully supervised medical image segmentation. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Runmin Jiang , Zhaoxin Fan , Junhao Wu , Lenghan Zhu , Xin Huang , Tianyang Wang , Heng Huang , Min Xu

Deep neural networks (DNNs) have demonstrated exceptional performance across various image segmentation tasks. However, the process of preparing datasets for training segmentation DNNs is both labor-intensive and costly, as it typically…

Computer Vision and Pattern Recognition · Computer Science 2025-01-24 Yixin Zhang , Shen Zhao , Hanxue Gu , Maciej A. Mazurowski

The differentiation between pathological subtypes of non-small cell lung cancer (NSCLC) is an essential step in guiding treatment options and prognosis. However, current clinical practice relies on multi-step staining and labelling…

Quantitative Methods · Quantitative Biology 2026-03-10 Zhenya Zang , David A Dorward , Katherine E Quiohilag , Andrew DJ Wood , James R Hopgood , Ahsan R Akram , Qiang Wang

Non-destructive 3D imaging of large multi-particulate samples is essential for quantifying particle-level properties, such as size, shape, and spatial distribution, across applications in mining, materials science, and geology. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Philipp D. Lösel , Aleese Barron , Yulai Zhang , Matthias Fabian , Benjamin Young , Nicolas Francois , Andrew M. Kingston

While deep learning strategies achieve outstanding results in computer vision tasks, one issue remains: The current strategies rely heavily on a huge amount of labeled data. In many real-world problems, it is not feasible to create such an…

Computer Vision and Pattern Recognition · Computer Science 2021-10-14 Lars Schmarje , Monty Santarossa , Simon-Martin Schröder , Reinhard Koch

High-quality labeled data is essential to successfully train supervised machine learning models. Although a large amount of unlabeled data is present in the medical domain, labeling poses a major challenge: medical professionals who can…

Machine Learning · Computer Science 2020-04-21 Abhijeet Parida , Aadhithya Sankar , Rami Eisawy , Tom Finck , Benedikt Wiestler , Franz Pfister , Julia Moosbauer

Deep learning models benefit from training with a large dataset (labeled or unlabeled). Following this motivation, we present an approach to learn a deep learning model for the automatic segmentation of Organs at Risk (OARs) in cervical…

Image and Video Processing · Electrical Eng. & Systems 2023-02-22 Monika Grewal , Dustin van Weersel , Henrike Westerveld , Peter A. N. Bosman , Tanja Alderliesten

Active learning (AL) is an effective approach to select the most informative samples to label so as to reduce the annotation cost. Existing AL methods typically work under the closed-set assumption, i.e., all classes existing in the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Linhao Qu , Yingfan Ma , Zhiwei Yang , Manning Wang , Zhijian Song

Supervised object detection has been proven to be successful in many benchmark datasets achieving human-level performances. However, acquiring a large amount of labeled image samples for supervised detection training is tedious,…

Computer Vision and Pattern Recognition · Computer Science 2021-05-12 Bishwo Adhikari , Esa Rahtu , Heikki Huttunen

Deep learning has proven to be more effective than other methods in medical image analysis, including the seemingly simple but challenging task of segmenting individual cells, an essential step for many biological studies. Comparative…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Valentina Vadori , Antonella Peruffo , Jean-Marie Graïc , Livio Finos , Livio Corain , Enrico Grisan

Instance segmentation is a fundamental vision task that aims to recognize and segment each object in an image. However, it requires costly annotations such as bounding boxes and segmentation masks for learning. In this work, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Xinlong Wang , Zhiding Yu , Shalini De Mello , Jan Kautz , Anima Anandkumar , Chunhua Shen , Jose M. Alvarez

We propose a new deep learning approach for medical imaging that copes with the problem of a small training set, the main bottleneck of deep learning, and apply it for classification of healthy and cancer cells acquired by quantitative…

Image and Video Processing · Electrical Eng. & Systems 2018-12-31 Moran Rubin , Omer Stein , Nir A. Turko , Yoav Nygate , Darina Roitshtain , Lidor Karako , Itay Barnea , Raja Giryes , Natan T. Shaked
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