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When considering binary strings, it's natural to wonder how many distinct subsequences might exist in a given string. Given that there is an existing algorithm which provides a straightforward way to compute the number of distinct…

Combinatorics · Mathematics 2023-06-22 Yonah Biers-Ariel , Anant Godbole , Elizabeth Kelley

Recurrent Neural Networks (RNNs) have been proven to be effective in modeling sequential data and they have been applied to boost a variety of tasks such as document classification, speech recognition and machine translation. Most of…

Computation and Language · Computer Science 2018-08-21 Zhiwei Wang , Yao Ma , Dawei Yin , Jiliang Tang

One of the most critical problems in the field of string algorithms is the longest common subsequence problem (LCS). The problem is NP-hard for an arbitrary number of strings but can be solved in polynomial time for a fixed number of…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-09-19 Soroush Vahidi , Baruch Schieber , Zhihui Du , David A. Bader

In this paper, we consider a variant of the classical algorithmic problem of checking whether a given word $v$ is a subsequence of another word $w$. More precisely, we consider the problem of deciding, given a number $p$ (defining a…

Formal Languages and Automata Theory · Computer Science 2024-09-16 Maria Kosche , Tore Koß , Florin Manea , Viktoriya Pak

The linear complexity of a sequence $s$ is one of the measures of its predictability. It represents the smallest degree of a linear recursion which the sequence satisfies. There are several algorithms to find the linear complexity of a…

Cryptography and Security · Computer Science 2019-12-30 Yeow Meng Chee , Johan Chrisnata , Tuvi Etzion , Han Mao Kiah

Scientists aim to extract simplicity from observations of the complex world. An important component of this process is the exploration of data in search of trends. In practice, however, this tends to be more of an art than a science. Among…

Machine Learning · Computer Science 2021-08-11 Dalya Baron , Brice Ménard

Labeling of DNA molecules is a fundamental technique for DNA visualization and analysis. This process was mathematically modeled in [1], where the received sequence indicates the positions of the used labels. In this work, we develop error…

Information Theory · Computer Science 2025-11-04 Dganit Hanania , Eitan Yaakobi

Phylogenetic networks are increasingly used in evolutionary biology to represent the history of species that have undergone reticulate events such as horizontal gene transfer, hybrid speciation and recombination. One of the most fundamental…

Populations and Evolution · Quantitative Biology 2016-10-07 Philippe Gambette , Leo van Iersel , Steven Kelk , Fabio Pardi , Celine Scornavacca

Finding an Approximate Longest Common Substring (ALCS) within a given set $S=\{s_1,s_2,\ldots,s_m\}$ of $m \ge 2$ strings is a key problem in computational biology, such as identifying related mutations across multiple genetic sequences. We…

Data Structures and Algorithms · Computer Science 2025-09-22 Hamed Hasibi , Neerja Mhaskar , W. F. Smyth

Constant-recursive sequences are those which satisfy a linear recurrence, so that later terms can be obtained as a linear combination of the previous ones. The rank of a constant-recursive sequence is the minimal number of previous terms…

Number Theory · Mathematics 2025-01-27 Eric Rowland , Jesus Sistos Barron

Applying machine learning to biological sequences - DNA, RNA and protein - has enormous potential to advance human health, environmental sustainability, and fundamental biological understanding. However, many existing machine learning…

Machine Learning · Statistics 2023-04-11 Alan Nawzad Amin , Eli Nathan Weinstein , Debora Susan Marks

DNA sequence alignment is important today as it is usually the first step in finding gene mutation, evolutionary similarities, protein structure, drug development and cancer treatment. Covid-19 is one recent example. There are many…

Genomics · Quantitative Biology 2023-06-01 Suchindra , Preetam Nagaraj

We present an algorithm computing the longest periodic subsequence of a string of length $n$ in $O(n^7)$ time with $O(n^4)$ words of space. We obtain improvements when restricting the exponents or extending the search allowing the reported…

Data Structures and Algorithms · Computer Science 2022-02-16 Hideo Bannai , Tomohiro I , Dominik Köppl

Sequencing by synthesis is the underlying technology for many next-generation DNA sequencing platforms. We developed a new model, the fixed flow cycle model, to derive the distributions of sequence length for a given number of flow cycles…

Genomics · Quantitative Biology 2024-05-28 Yong Kong

The Longest Common Increasing Subsequence problem (LCIS) is a natural variant of the celebrated Longest Common Subsequence (LCS) problem. For LCIS, as well as for LCS, there is an $O(n^2)$-time algorithm and a SETH-based conditional lower…

Data Structures and Algorithms · Computer Science 2020-01-31 Lech Duraj

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of…

The problem of reconstructing strings from their substring spectra has a long history and in its most simple incarnation asks for determining under which conditions the spectrum uniquely determines the string. We study the problem of coded…

Information Theory · Computer Science 2019-04-24 Ryan Gabrys , Olgica Milenkovic

A central problem in comparative genomics consists in computing a (dis-)similarity measure between two genomes, e.g. in order to construct a phylogeny. All the existing measures are defined on genomes without duplicates. However, we know…

Quantitative Methods · Quantitative Biology 2008-12-18 Sébastien Angibaud , Guillaume Fertin , Irena Rusu , Annelyse Thevenin , Stéphane Vialette

A heapable sequence is a sequence of numbers that can be arranged in a "min-heap data structure". Finding a longest heapable subsequence of a given sequence was proposed by Byers, Heeringa, Mitzenmacher, and Zervas (ANALCO 2011) as a…

Data Structures and Algorithms · Computer Science 2021-10-07 Karthekeyan Chandrasekaran , Elena Grigorescu , Gabriel Istrate , Shubhang Kulkarni , Young-San Lin , Minshen Zhu

Studying the computational complexity of problems is one of the - if not the - fundamental questions in computer science. Yet, surprisingly little is known about the computational complexity of many central problems in data mining. In this…

Computational Complexity · Computer Science 2017-09-05 Stefan Neumann , Pauli Miettinen