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We propose an algorithm, guided variational autoencoder (Guided-VAE), that is able to learn a controllable generative model by performing latent representation disentanglement learning. The learning objective is achieved by providing…

Computer Vision and Pattern Recognition · Computer Science 2020-04-06 Zheng Ding , Yifan Xu , Weijian Xu , Gaurav Parmar , Yang Yang , Max Welling , Zhuowen Tu

Variational autoencoders (VAEs) are widely used deep generative models capable of learning unsupervised latent representations of data. Such representations are often difficult to interpret or control. We consider the problem of…

Machine Learning · Computer Science 2018-12-18 Jack Klys , Jake Snell , Richard Zemel

Previous approaches to generate shapes in a 3D setting train a GAN on the latent space of an autoencoder (AE). Even though this produces convincing results, it has two major shortcomings. As the GAN is limited to reproduce the dataset the…

Computer Vision and Pattern Recognition · Computer Science 2021-07-23 Moritz Ibing , Isaak Lim , Leif Kobbelt

Objective: This paper investigates how generative models, trained on ground-truth images, can be used \changes{as} priors for inverse problems, penalizing reconstructions far from images the generator can produce. The aim is that learned…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Margaret Duff , Ivor J. A. Simpson , Matthias J. Ehrhardt , Neill D. F. Campbell

Medical image segmentation is crucial for clinical diagnosis and treatment planning. Traditional methods typically produce a single segmentation mask, failing to capture inherent uncertainty. Recent generative models enable the creation of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Huynh Trinh Ngoc , Toan Nguyen Hai , Ba Luong Son , Long Tran Quoc

Synthetic data generation is of great interest in diverse applications, such as for privacy protection. Deep generative models, such as variational autoencoders (VAEs), are a popular approach for creating such synthetic datasets from…

Machine Learning · Statistics 2021-05-17 Kiana Farhadyar , Federico Bonofiglio , Daniela Zoeller , Harald Binder

Masked autoencoder (MAE) is a promising self-supervised pre-training technique that can improve the representation learning of a neural network without human intervention. However, applying MAE directly to volumetric medical images poses…

Computer Vision and Pattern Recognition · Computer Science 2023-08-24 Jia-Xin Zhuang , Luyang Luo , Hao Chen

Objective: fMRI and derived measures such as functional connectivity (FC) have been used to predict brain age, general fluid intelligence, psychiatric disease status, and preclinical neurodegenerative disease. However, it is not always…

Quantitative Methods · Quantitative Biology 2024-05-14 Anton Orlichenko , Gang Qu , Ziyu Zhou , Anqi Liu , Hong-Wen Deng , Zhengming Ding , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Variational autoencoder (VAE) is a widely used generative model for learning latent representations. Burda et al. in their seminal paper showed that learning capacity of VAE is limited by over-pruning. It is a phenomenon where a significant…

Machine Learning · Computer Science 2020-08-10 Rayyan Ahmad Khan , Muhammad Umer Anwaar , Martin Kleinsteuber

Variational auto-encoders (VAEs) are a popular and powerful deep generative model. Previous works on VAEs have assumed a factorized likelihood model, whereby the output uncertainty of each pixel is assumed to be independent. This…

Machine Learning · Statistics 2026-05-14 Gara Dorta , Sara Vicente , Lourdes Agapito , Neill D. F. Campbell , Ivor Simpson

Variational autoencoders (VAEs) are powerful deep generative models widely used to represent high-dimensional complex data through a low-dimensional latent space learned in an unsupervised manner. In the original VAE model, the input data…

Machine Learning · Computer Science 2022-07-05 Laurent Girin , Simon Leglaive , Xiaoyu Bie , Julien Diard , Thomas Hueber , Xavier Alameda-Pineda

Although unsupervised generative modeling of an image dataset using a Variational AutoEncoder (VAE) has been used to detect anomalous images, or anomalous regions in images, recent works have shown that this method often identifies images…

Computer Vision and Pattern Recognition · Computer Science 2020-08-13 David Dehaene , Pierre Eline

Deep generative models have demonstrated successful applications in learning non-linear data distributions through a number of latent variables and these models use a nonlinear function (generator) to map latent samples into the data space.…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Pourya Shamsolmoali , Masoumeh Zareapoor , Huiyu Zhou , Dacheng Tao , Xuelong Li

We present two deep generative models based on Variational Autoencoders to improve the accuracy of drug response prediction. Our models, Perturbation Variational Autoencoder and its semi-supervised extension, Drug Response Variational…

Machine Learning · Statistics 2017-07-07 Ladislav Rampasek , Daniel Hidru , Petr Smirnov , Benjamin Haibe-Kains , Anna Goldenberg

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Machine learning using transformers has shown great potential in medical imaging, but its real-world applicability remains limited due to the scarcity of annotated data. In this study, we propose a practical framework for the few-shot…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Mengyu Li , Guoyao Shen , Chad W. Farris , Xin Zhang

Variational Autoencoders (VAEs) are powerful generative models widely used for learning interpretable latent spaces, quantifying uncertainty, and compressing data for downstream generative tasks. VAEs typically rely on diagonal Gaussian…

Machine Learning · Computer Science 2025-06-03 Peter Sorrenson , Lukas Lührs , Hans Olischläger , Ullrich Köthe

Variational Autoencoders (VAE) and their variants have been widely used in a variety of applications, such as dialog generation, image generation and disentangled representation learning. However, the existing VAE models have some…

Machine Learning · Computer Science 2020-06-23 Huajie Shao , Shuochao Yao , Dachun Sun , Aston Zhang , Shengzhong Liu , Dongxin Liu , Jun Wang , Tarek Abdelzaher

Interpreting computations in the visual cortex as learning and inference in a generative model of the environment has received wide support both in neuroscience and cognitive science. However, hierarchical computations, a hallmark of visual…

Neurons and Cognition · Quantitative Biology 2022-06-02 Ferenc Csikor , Balázs Meszéna , Bence Szabó , Gergő Orbán

This paper introduces a modified variational autoencoder (VAEs) that contains an additional neural network branch. The resulting branched VAE (BVAE) contributes a classification component based on the class labels to the total loss and…

Machine Learning · Computer Science 2024-01-08 Ahmed Salah , David Yevick