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Discrete choice models are essential for modelling various decision-making processes in human behaviour. However, the specification of these models has depended heavily on domain knowledge from experts, and the fully automated but…

Machine Learning · Computer Science 2025-07-16 Fumiyasu Makinoshima , Tatsuya Mitomi , Fumiya Makihara , Eigo Segawa

Denoising diffusion models (DDMs) offer a flexible framework for sampling from high dimensional data distributions. DDMs generate a path of probability distributions interpolating between a reference Gaussian distribution and a data…

Machine Learning · Statistics 2024-12-12 Christopher Williams , Andrew Campbell , Arnaud Doucet , Saifuddin Syed

A leading goal for climate science and weather risk management is to accurately model both the physics and statistics of extreme events. These two goals are fundamentally at odds: the higher a computational model's resolution, the more…

Atmospheric and Oceanic Physics · Physics 2024-02-06 Justin Finkel , Paul A. O'Gorman

In stochastic systems, numerically sampling the relevant trajectories for the estimation of the large deviation statistics of time-extensive observables requires overcoming their exponential (in space and time) scarcity. The optimal way to…

Statistical Mechanics · Physics 2021-01-14 Tom H. E. Oakes , Adam Moss , Juan P. Garrahan

Simulation based or dynamic probabilistic risk assessment methodologies were primarily developed for proving a more realistic and complete representation of complex systems accident response. Such simulation based methodologies have proven…

Systems and Control · Electrical Eng. & Systems 2021-09-30 Parhizkar Tarannom , Mosleh Ali

The study by Jung et al. (Jung H, Covino R, Arjun A, et al., Nat Comput Sci. 3:334-345 (2023)) introduced Artificial Intelligence for Molecular Mechanism Discovery (AIMMD), a novel sampling algorithm that integrates machine learning to…

Computational Physics · Physics 2026-02-06 Porhouy Minh , Sapna Sarupria

We introduce DIFFTACTILE, a physics-based differentiable tactile simulation system designed to enhance robotic manipulation with dense and physically accurate tactile feedback. In contrast to prior tactile simulators which primarily focus…

Robotics · Computer Science 2024-03-14 Zilin Si , Gu Zhang , Qingwei Ben , Branden Romero , Zhou Xian , Chao Liu , Chuang Gan

Atomistic modelling of phase transitions, chemical reactions, or other rare events that involve overcoming high free energy barriers usually entails prohibitively long simulation times. Introducing a bias potential as a function of an…

Computational Physics · Physics 2019-11-06 Federico Giberti , Bingqing Cheng , Gareth Aneurin Tribello , Michele Ceriotti

A wide variety of numerical methods are evaluated and compared for solving the stochastic differential equations encountered in molecular dynamics. The methods are based on the application of deterministic impulses, drifts, and Brownian…

Computational Physics · Physics 2013-05-14 Benedict Leimkuhler , Charles Matthews

Diffusion Probabilistic Models (DPM) have shown remarkable efficacy in the synthesis of high-quality images. However, their inference process characteristically requires numerous, potentially hundreds, of iterative steps, which could…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Mingxiao Li , Tingyu Qu , Ruicong Yao , Wei Sun , Marie-Francine Moens

Accurate characterization of subsurface heterogeneity is challenging but essential for applications such as reservoir pressure management, geothermal energy extraction and CO$_2$, H$_2$, and wastewater injection operations. This challenge…

Machine Learning · Computer Science 2026-04-16 Harun Ur Rashid , Mingxin Li , Aleksandra Pachalieva , Georg Stadler , Daniel O'Malley

We present DiSH-Sim, a simulator for large discrete models of biological signal transduction pathways, capable of simulating networks with multi-valued elements in both deterministic and stochastic manner. We focus on order of update and…

Molecular Networks · Quantitative Biology 2017-05-09 Khaled Sayed , Yu-Hsin Kuo , Anuva Kulkarni , Natasa Miskov-Zivanov

Diffusion Probabilistic Models (DPMs) have demonstrated exceptional capability of generating high-quality and diverse images, but their practical application is hindered by the intensive computational cost during inference. The DPM…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Jen-Yuan Huang

Denoising diffusion bridge models (DDBMs) are a powerful variant of diffusion models for interpolating between two arbitrary paired distributions given as endpoints. Despite their promising performance in tasks like image translation, DDBMs…

Machine Learning · Computer Science 2025-05-01 Kaiwen Zheng , Guande He , Jianfei Chen , Fan Bao , Jun Zhu

Assessing the risk of low-probability high-impact transient instability (TI) events is crucial for ensuring robust and stable power system operation under high uncertainty. However, direct Monte Carlo (DMC) simulation for rare TI event…

Systems and Control · Electrical Eng. & Systems 2025-03-05 Jingyu Liu , Xiaoting Wang , Xiaozhe Wang

Simulating spontaneous structural rearrangements in macromolecules with classical Molecular Dynamics (MD) is an outstanding challenge. Conventional supercomputers can access time intervals up to tens of $\mu$s, while many key events occur…

Biological Physics · Physics 2026-03-19 Danial Ghamari , Roberto Covino , Pietro Faccioli

Sensitivity analysis of biochemical reactions aims at quantifying the dependence of the reaction dynamics on the reaction rates. The computation of the parameter sensitivities, however, poses many computational challenges when taking…

Molecular Networks · Quantitative Biology 2018-11-07 Vo Hong Thanh , Roberto Zunino , Corrado Priami

Trajectory prediction is a fundamental task in Autonomous Vehicles (AVs) and Intelligent Transportation Systems (ITS), supporting efficient motion planning and real-time traffic safety management. Diffusion models have recently demonstrated…

Artificial Intelligence · Computer Science 2025-10-02 Bingzhang Wang , Kehua Chen , Yinhai Wang

The next generation of force fields for molecular dynamics will be developed using a wealth of data. Training systematically with experimental data remains a challenge, however, especially for machine learning potentials. Differentiable…

Biomolecules · Quantitative Biology 2025-04-16 Joe G Greener

The interplay between stochastic chemical reactions and diffusion can generate rich spatiotemporal patterns. While the timescale for individual reaction or diffusion events may be very fast, the timescales for organization can be much…

Statistical Mechanics · Physics 2023-12-12 Schuyler B. Nicholson , Todd R. Gingrich
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