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Reliable seizure detection from electroencephalography (EEG) time series is a high-priority clinical goal, yet the acquisition cost and scarcity of labeled EEG data limit the performance of machine learning methods. This challenge is…

Methodology · Statistics 2026-01-30 Nina Moutonnet , Joshua Corneck , Felipe Tobar , Danilo Mandic

The neonatal period is the most vulnerable time for the development of seizures. Seizures in the immature brain lead to detrimental consequences, therefore require early diagnosis. The gold-standard for neonatal seizure detection currently…

Classification models for electroencephalogram (EEG) data show a large decrease in performance when evaluated on unseen test sub jects. We reduce this performance decrease using new regularization techniques during model training. We…

Machine Learning · Computer Science 2023-10-16 Niklas Smedemark-Margulies , Ye Wang , Toshiaki Koike-Akino , Jing Liu , Kieran Parsons , Yunus Bicer , Deniz Erdogmus

Objective. Supervised learning paradigms are often limited by the amount of labeled data that is available. This phenomenon is particularly problematic in clinically-relevant data, such as electroencephalography (EEG), where labeling can be…

Machine Learning · Statistics 2020-08-03 Hubert Banville , Omar Chehab , Aapo Hyvärinen , Denis-Alexander Engemann , Alexandre Gramfort

Real time seizure detection is a fundamental problem in computational neuroscience towards diagnosis and treatment's improvement of epileptic disease. We propose a real-time computational method for tracking and detection of epileptic…

Quantitative Methods · Quantitative Biology 2024-06-17 Ximena Fernández , Diego Mateos

In the context of electroencephalogram (EEG)-based driver drowsiness recognition, it is still challenging to design a calibration-free system, since EEG signals vary significantly among different subjects and recording sessions. Many…

Signal Processing · Electrical Eng. & Systems 2022-02-21 Jian Cui , Zirui Lan , Olga Sourina , Wolfgang Müller-Wittig

The Epilepsies are a common, chronic neurological disorder affecting more than 50 million individuals across the globe. It is characterized by unprovoked, recurring (similar or different type) seizures which are commonly diagnosed through…

Signal Processing · Electrical Eng. & Systems 2021-08-03 Palak Handa , Monika Mathur , Nidhi Goel

Accurate automated analysis of electroencephalography (EEG) would largely help clinicians effectively monitor and diagnose patients with various brain diseases. Compared to supervised learning with labelled disease EEG data which can train…

Machine Learning · Computer Science 2022-07-05 Yaojia Zheng , Zhouwu Liu , Rong Mo , Ziyi Chen , Wei-shi Zheng , Ruixuan Wang

Current pain assessment within hospitals often relies on self-reporting or non-specific EKG vital signs. This system leaves critically ill, sedated, and cognitively impaired patients vulnerable to undertreated pain and opioid overuse.…

Machine Learning · Computer Science 2025-10-08 Aavid Mathrawala , Dhruv Kurup , Josie Lau

Scalp electroencephalography (EEG) and intracranial EEG (iEEG) are vital for epilepsy diagnosis and treatment. Their unified analysis offers the potential to harness the complementary strengths of each modality but is challenging due to…

Neurons and Cognition · Quantitative Biology 2025-06-23 Runkai Zhang , Hua Yu , John Q. Gan , Haixian Wang

Epilepsy is a disorder of the brain denoted by frequent seizures. The symptoms of seizure include confusion, abnormal staring, and rapid, sudden, and uncontrollable hand movements. Epileptic seizure detection methods involve neurological…

Neonates are highly susceptible to seizures, often leading to short or long-term neurological impairments. However, clinical manifestations of neonatal seizures are subtle and often lead to misdiagnoses. This increases the risk of…

Prediction of seizure before they occur is vital for bringing normalcy to the lives of patients. Researchers employed machine learning methods using hand-crafted features for seizure prediction. However, ML methods are too complicated to…

Machine Learning · Computer Science 2020-12-02 Khansa Rasheed , Junaid Qadir , Terence J. O'Brien , Levin Kuhlmann , Adeel Razi

We investigate the suitability of selected measures of complexity based on recurrence quantification analysis and recurrence networks for an identification of pre-seizure states in multi-day, multi-channel, invasive electroencephalographic…

Information transmission in the human brain is a fundamentally dynamic network process. In partial epilepsy, this process is perturbed and highly synchronous seizures originate in a local network, the so-called epileptogenic zone (EZ),…

Neurons and Cognition · Quantitative Biology 2019-06-19 Simona Olmi , Spase Petkoski , Maxime Guye , Fabrice Bartolomei , Viktor Jirsa

This study presents a novel approach for EEG-based seizure detection leveraging a BERT-based model. The model, BENDR, undergoes a two-phase training process. Initially, it is pre-trained on the extensive Temple University Hospital EEG…

Epilepsy is one of the most common neurological disorders affecting up to 1% of the world's population and approximately 2.5 million people in the United States. Seizures in more than 30% of epilepsy patients are refractory to…

Signal Processing · Electrical Eng. & Systems 2019-08-23 Md Abu Sayeed , Saraju P. Mohanty , Elias Kougianos

Patients with epilepsy can manifest short, sub-clinical epileptic "bursts" in addition to full-blown clinical seizures. We believe the relationship between these two classes of events---something not previously studied…

Machine Learning · Statistics 2014-07-29 Drausin F. Wulsin , Emily B. Fox , Brian Litt

Electroencephalography (EEG) provides a non-invasive, highly accessible, and cost-effective approach for detecting Alzheimer's disease (AD). However, existing methods, whether based on handcrafted feature engineering or standard deep…

Machine Learning · Computer Science 2026-02-03 Yihe Wang , Nan Huang , Nadia Mammone , Marco Cecchi , Xiang Zhang

A methodology for understanding and de- tecting nonconvulsive seizures in individuals with sub- arachnoid hemorrhage is introduced. Specifically, begin- ning with an EEG signal, the power spectrum is esti- mated yielding a multivariate time…

Neurons and Cognition · Quantitative Biology 2013-06-03 D J Albers , J Claassen , M J Schmidt , G Hripcsak