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Deep Neural Networks (DNN) are known to be vulnerable to adversarial samples, the detection of which is crucial for the wide application of these DNN models. Recently, a number of deep testing methods in software engineering were proposed…

Machine Learning · Computer Science 2021-07-16 Zuohui Chen , Renxuan Wang , Jingyang Xiang , Yue Yu , Xin Xia , Shouling Ji , Qi Xuan , Xiaoniu Yang

Generative adversarial imitation learning (GAIL) is a popular inverse reinforcement learning approach for jointly optimizing policy and reward from expert trajectories. A primary question about GAIL is whether applying a certain policy…

Machine Learning · Computer Science 2020-06-26 Ziwei Guan , Tengyu Xu , Yingbin Liang

This work studies training generative adversarial networks under the federated learning setting. Generative adversarial networks (GANs) have achieved advancement in various real-world applications, such as image editing, style transfer,…

Machine Learning · Computer Science 2020-07-21 Chenyou Fan , Ping Liu

Geometric Representation Learning (GRL) aims to approximate the non-Euclidean topology of high-dimensional data through discrete graph structures, grounded in the manifold hypothesis. However, traditional static graph construction methods…

Machine Learning · Computer Science 2026-01-14 Chaoqun Fei , Huanjiang Liu , Tinglve Zhou , Yangyang Li , Tianyong Hao

Graph neural networks (GNNs) are prominent for their effectiveness in processing graph data for semi-supervised node classification tasks. Most works of GNNs assume that the observed structure accurately represents the underlying node…

Machine Learning · Computer Science 2024-11-08 Shuangjie Li , Jiangqing Song , Baoming Zhang , Gaoli Ruan , Junyuan Xie , Chongjun Wang

Adversarial attacks on graphs have posed a major threat to the robustness of graph machine learning (GML) models. Naturally, there is an ever-escalating arms race between attackers and defenders. However, the strategies behind both sides…

Machine Learning · Computer Science 2021-11-09 Qinkai Zheng , Xu Zou , Yuxiao Dong , Yukuo Cen , Da Yin , Jiarong Xu , Yang Yang , Jie Tang

Existing drug discovery pipelines take 5-10 years and cost billions of dollars. Computational approaches aim to sample from regions of the whole molecular and solid-state compounds called chemical space which could be on the order of 1060 .…

Emerging Technologies · Computer Science 2021-01-12 Junde Li , Rasit Topaloglu , Swaroop Ghosh

Application of realism enhancement methods, particularly in real-time and resource-constrained settings, has been frustrated by the expense of existing methods. These achieve high quality results only at the cost of long runtimes and high…

Graphics · Computer Science 2023-06-08 Arturo Salmi , Szabolcs Cséfalvay , James Imber

Graph neural network (GNN) has captured wide attention due to its capability of graph representation learning for graph-structured data. However, the distributed data silos limit the performance of GNN. Vertical federated learning (VFL), an…

Machine Learning · Computer Science 2024-11-06 Jinyin Chen , Wenbo Mu , Luxin Zhang , Guohan Huang , Haibin Zheng , Yao Cheng

Graph Contrastive Learning (GCL) has recently emerged as a promising graph self-supervised learning framework for learning discriminative node representations without labels. The widely adopted objective function of GCL benefits from two…

Machine Learning · Computer Science 2024-11-05 Yunhui Liu , Tieke He , Tao Zheng , Jianhua Zhao

Generative adversarial networks, which can generate metasurfaces based on a training set of high performance device layouts, have the potential to significantly reduce the computational cost of the metasurface design process. However, basic…

Computational Physics · Physics 2019-12-03 Fufang Wen , Jiaqi Jiang , Jonathan A. Fan

Sufficient supervised information is crucial for any machine learning models to boost performance. However, labeling data is expensive and sometimes difficult to obtain. Active learning is an approach to acquire annotations for data from a…

Machine Learning · Computer Science 2019-06-18 Quan Kong , Bin Tong , Martin Klinkigt , Yuki Watanabe , Naoto Akira , Tomokazu Murakami

This paper studies the problem of graph-level clustering, which is a novel yet challenging task. This problem is critical in a variety of real-world applications such as protein clustering and genome analysis in bioinformatics. Recent years…

Machine Learning · Computer Science 2023-03-09 Wei Ju , Yiyang Gu , Binqi Chen , Gongbo Sun , Yifang Qin , Xingyuming Liu , Xiao Luo , Ming Zhang

Generative AI has the potential to revolutionize drug discovery. Yet, despite recent advances in deep learning, existing models cannot generate molecules that satisfy all desired physicochemical properties. Herein, we describe IDOLpro, a…

Chemical Physics · Physics 2025-04-29 Amit Kadan , Kevin Ryczko , Erika Lloyd , Adrian Roitberg , Takeshi Yamazaki

Machine learning in drug discovery has been focused on virtual screening of molecular libraries using discriminative models. Generative models are an entirely different approach that learn to represent and optimize molecules in a continuous…

Quantitative Methods · Quantitative Biology 2020-11-17 Matthew Ragoza , Tomohide Masuda , David Ryan Koes

Graph Neural Networks (GNNs) have demonstrated remarkable efficacy in tackling a wide array of graph-related tasks across diverse domains. However, a significant challenge lies in their propensity to generate biased predictions,…

Machine Learning · Computer Science 2025-01-03 Abdullah Alchihabi , Yuhong Guo

Deep neural networks have achieved state-of-the-art performance in a wide range of recognition/classification tasks. However, when applying deep learning to real-world applications, there are still multiple challenges. A typical challenge…

Machine Learning · Computer Science 2021-02-10 Xin Sun , Zhenning Yang , Chi Zhang , Guohao Peng , Keck-Voon Ling

Graph neural networks, a popular class of models effective in a wide range of graph-based learning tasks, have been shown to be vulnerable to adversarial attacks. While the majority of the literature focuses on such vulnerability in…

Machine Learning · Statistics 2021-11-05 Xingchen Wan , Henry Kenlay , Binxin Ru , Arno Blaas , Michael A. Osborne , Xiaowen Dong

Graph representation learning is a fast-growing field where one of the main objectives is to generate meaningful representations of graphs in lower-dimensional spaces. The learned embeddings have been successfully applied to perform various…

Machine Learning · Computer Science 2021-12-21 Md. Khaledur Rahman , Ariful Azad

Differentiable solvers for the linear assignment problem (LAP) have attracted much research attention in recent years, which are usually embedded into learning frameworks as components. However, previous algorithms, with or without learning…

Machine Learning · Computer Science 2022-01-07 He Liu , Tao Wang , Congyan Lang , Songhe Feng , Yi Jin , Yidong Li