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Light scattering by tissue severely limits how deep beneath the surface one can image, and the spatial resolution one can obtain from these images. Diffuse optical tomography (DOT) is one of the most powerful techniques for imaging deep…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Yongyi Zhao , Ankit Raghuram , Hyun K. Kim , Andreas H. Hielscher , Jacob T. Robinson , Ashok Veeraraghavan

Near infrared diffuse optical tomography (DOT) provides an imaging modality for the oxygenation of tissue. In this paper, we propose a novel machine learning algorithm based on time-domain radiative transfer equation. We use temporal…

Medical Physics · Physics 2020-11-26 Yu-ichi Takamizu , Masayuki Umemura , Hidenobu Yajima , Makito Abe , Yoko Hoshi

Time-domain sampling of arbitrary electric fields with sub-cycle resolution enables a complete time-frequency analysis of a system's response to electromagnetic illumination. This provides access to dynamic information that is not provided…

Laser-driven proton sources have long been developed with an eye on their potential for medical application to radiation therapy. These sources are compact, versatile, and show peculiar characteristics such as extreme instantaneous dose…

The ability to control the speed and polarisation of light pulses will allow for faster data flow in optical networks of the future. Optical delay and switching have been achieved using slow-light techniques in various media, including…

Atomic Physics · Physics 2009-04-08 Paul Siddons , Nia C Bell , Yifei Cai , Charles S Adams , Ifan G Hughes

Electrical pulse stimulation drives many important physical phenomena in condensed matter as well as in electronic systems and devices. Often, nanoscopic and mesoscopic mechanisms are hypothesized, but methods to image electrically driven…

Mesoscale and Nanoscale Physics · Physics 2023-06-05 Thomas E Gage , Daniel B Durham , Haihua Liu , Supratik Guha , Ilke Arslan , Charudatta Phatak

Radio pulses from pulsars are affected by plasma dispersion, which results in a frequency-dependent propagation delay. Variations in the magnitude of this effect lead to an additional source of red noise in pulsar timing experiments,…

High brightness and low coherence laser sources with wideband tunability are essential for many full-field imaging applications aiming for high contrast and speckle free performance. However, this combination of parameters is challenging to…

Optics · Physics 2026-05-12 Xinyang Liu , Matias Koivurova , Regina Gumenyuk

Based on the similarity of paraxial diffraction and dispersion mathematical descriptions, the temporal imaging of optical pulses combines linear dispersive filters and quadratic phase modulations operating as time lenses. We consider…

Objective: Time-domain diffuse optical imaging (DOI) requires accurate forward models for photon propagation in scattering media. However, existing simulators lack comprehensive experimental validation, especially for non-contact…

Light scattering imposes a major obstacle for imaging objects seated deeply in turbid media, such as biological tissues and foggy air. Diffuse optical tomography (DOT) tackles scattering by volumetrically recovering the optical absorbance…

We demonstrate that time-domain ptychography, a recently introduced ultrafast pulse reconstruction modality, has properties ideally suited for the temporal characterization of complex light pulses with large time-bandwidth products as it…

Recent advances in laser technology allow us to follow electronic motion at its natural time-scale with ultra-fast time resolution, leading the way towards attosecond physics experiments of extreme precision. In this work, we assess the use…

Other Condensed Matter · Physics 2016-06-22 Jessica Walkenhorst , Umberto De Giovannini , Alberto Castro , Angel Rubio

In this work, we are concerned with the diffusive optical tomography (DOT) problem in the case when only one or two pairs of Cauchy data is available. We propose a simple and efficient direct sampling method (DSM) to locate inhomogeneities…

Mathematical Physics · Physics 2014-10-07 Yat Tin Chow , Kazufumi Ito , Keji Liu , Jun Zou

Diffuse optical tomography (DOT) utilises near-infrared light for imaging spatially distributed optical parameters, typically the absorption and scattering coefficients. The image reconstruction problem of DOT is an ill-posed inverse…

Computational Physics · Physics 2021-12-15 Meghdoot Mozumder , Andreas Hauptmann , Ilkka Nissilä , Simon R. Arridge , Tanja Tarvainen

Light scattering in inhomogeneous media induces wavefront distortions which pose an inherent limitation in many optical applications. Examples range from microscopy and nanosurgery to astronomy. In recent years, ongoing efforts have made…

Optics · Physics 2015-05-20 Ori Katz , Yaron Bromberg , Eran Small , Yaron Silberberg

Diffusion pore imaging is an extension of diffusion-weighted nuclear magnetic resonance imaging enabling the direct measurement of the shape of arbitrarily formed, closed pores by probing diffusion restrictions using the motion of…

Diffuse optical spectroscopy (DOS) techniques aim to characterize scattering media by examining their optical response to laser illumination. Time-domain DOS methods involve illuminating the medium with a laser pulse and using a fast…

Optics · Physics 2024-04-18 Connor Henley , Joseph Hollmann , Colin Meyer , Ramesh Raskar

Diffuse optical tomography (DOT) is an imaging modality which uses near-infrared light. Although iterative numerical schemes are commonly used for its inverse problem, correct solutions are not obtained unless good initial guesses are…

Numerical Analysis · Mathematics 2021-06-07 Yu Jiang , Manabu Machida , Norikazu Todoroki

Multiphoton microscopes employ femtosecond lasers as light sources because the high peak power of the ultrashort pulse allows for multiphoton excitation of fluorescence in the examined sample. However, such short pulses are susceptible to…

Optics · Physics 2024-08-13 Katarzyna Kunio , Jakub Bogusławski , Grzegorz Soboń
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