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Lung cancer, a severe form of malignant tumor that originates in the tissues of the lungs, can be fatal if not detected in its early stages. It ranks among the top causes of cancer-related mortality worldwide. Detecting lung cancer manually…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Santanu Roy , Shweta Singh , Palak Sahu , Ashvath Suresh , Debashish Das

Distant metastases (DM) refer to the dissemination of tumors, usually, beyond the organ where the tumor originated. They are the leading cause of death in patients with soft-tissue sarcomas (STSs). Positron emission tomography-computed…

Image and Video Processing · Electrical Eng. & Systems 2021-12-22 Yige Peng , Lei Bi , Ashnil Kumar , Michael Fulham , Dagan Feng , Jinman Kim

Lung cancer is the leading cause of patient mortality in the world. Early diagnosis of malignant pulmonary nodules in CT images can have a significant impact on reducing disease mortality and morbidity. In this work, we propose LMLCC-Net, a…

Image and Video Processing · Electrical Eng. & Systems 2025-11-27 Tasnia Binte Mamun , Adhora Madhuri , Nusaiba Sobir , Taufiq Hasan

Treatment decisions for brain metastatic disease rely on knowledge of the primary organ site, and currently made with biopsy and histology. Here we develop a novel deep learning approach for accurate non-invasive digital histology with…

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

Brain metastases occur frequently in patients with metastatic cancer. Early and accurate detection of brain metastases is very essential for treatment planning and prognosis in radiation therapy. To improve brain metastasis detection…

Brain metastasis segmentation poses a significant challenge in medical imaging due to the complex presentation and variability in size and location of metastases. In this study, we first investigate the impact of different imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-07-22 Yousef Sadegheih , Dorit Merhof

Lymph node (LN) assessment is an essential task in the routine radiology workflow, providing valuable insights for cancer staging, treatment planning and beyond. Identifying scatteredly-distributed and low-contrast LNs in 3D CT scans is…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Qinji Yu , Yirui Wang , Ke Yan , Dandan Zheng , Dashan Ai , Dazhou Guo , Zhanghexuan Ji , Yanzhou Su , Yun Bian , Na Shen , Xiaowei Ding , Le Lu , Xianghua Ye , Dakai Jin

Pathological lung segmentation (PLS) is an important, yet challenging, medical image application due to the wide variability of pathological lung appearance and shape. Because PLS is often a pre-requisite for other imaging analytics,…

Computer Vision and Pattern Recognition · Computer Science 2018-02-09 Adam P. Harrison , Ziyue Xu , Kevin George , Le Lu , Ronald M. Summers , Daniel J. Mollura

Segmentation of lymphoma lesions is challenging due to their varied sizes and locations in whole-body PET scans. This work presents a fully-automated segmentation technique using a multi-center dataset of diffuse large B-cell lymphoma…

We address the problem of supporting radiologists in the longitudinal management of lung cancer. Therefore, we proposed a deep learning pipeline, composed of four stages that completely automatized from the detection of nodules to the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-29 Xavier Rafael-Palou , Anton Aubanell , Mario Ceresa , Vicent Ribas , Gemma Piella , Miguel A. González Ballester

Precise segmentation of bladder walls and tumor regions is an essential step towards non-invasive identification of tumor stage and grade, which is critical for treatment decision and prognosis of patients with bladder cancer (BC). However,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-06 Jose Dolz , Xiaopan Xu , Jerome Rony , Jing Yuan , Yang Liu , Eric Granger , Christian Desrosiers , Xi Zhang , Ismail Ben Ayed , Hongbing Lu

Knowledge regarding the kinetics of metastatic tumor formation, as related to the growth of the primary tumor, represents a fundamental issue in cancer biology. Using an in vivo mammalian model, we show here that one can obtain useful…

Tissues and Organs · Quantitative Biology 2007-05-23 Steve P. Lee , Ji-Rong Sun , Hong Qian , William H. McBride , H. Rodney Withers

Risk stratification of lung nodules is a task of primary importance in lung cancer diagnosis. Any improvement in robust and accurate nodule characterization can assist in identifying cancer stage, prognosis, and improving treatment…

Computer Vision and Pattern Recognition · Computer Science 2017-10-27 Sarfaraz Hussein , Kunlin Cao , Qi Song , Ulas Bagci

Early detection of lung cancer is an effective way to improve the survival rate of patients. It is a critical step to have accurate detection of lung nodules in computed tomography (CT) images for the diagnosis of lung cancer. However, due…

Computer Vision and Pattern Recognition · Computer Science 2019-05-10 Haichao Cao , Hong Liu , Enmin Song , Guangzhi Ma , Xiangyang Xu , Renchao Jin , Tengying Liu , Chih-Cheng Hung

This paper introduces a novel deep-learning method for the automatic detection and segmentation of lung nodules, aimed at advancing the accuracy of early-stage lung cancer diagnosis. The proposed approach leverages a unique "Channel Squeeze…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mingxiu Sui , Jiacheng Hu , Tong Zhou , Zibo Liu , Likang Wen , Junliang Du

Accurately predicting and detecting interstitial lung disease (ILD) patterns given any computed tomography (CT) slice without any pre-processing prerequisites, such as manually delineated regions of interest (ROIs), is a clinically…

Computer Vision and Pattern Recognition · Computer Science 2017-01-23 Mingchen Gao , Ziyue Xu , Le Lu , Adam P. Harrison , Ronald M. Summers , Daniel J. Mollura

Early and accurate diagnosis of interstitial lung diseases (ILDs) is crucial for making treatment decisions, but can be challenging even for experienced radiologists. The diagnostic procedure is based on the detection and recognition of the…

Computer Vision and Pattern Recognition · Computer Science 2018-04-02 Marios Anthimopoulos , Stergios Christodoulidis , Lukas Ebner , Thomas Geiser , Andreas Christe , Stavroula Mougiakakou

Lung cancer (LC) ranks among the most frequently diagnosed cancers and is one of the most common causes of death for men and women worldwide. Computed Tomography (CT) images are the most preferred diagnosis method because of their low cost…

Image and Video Processing · Electrical Eng. & Systems 2025-08-11 Mobarak Abumohsen , Enrique Costa-Montenegro , Silvia García-Méndez , Amani Yousef Owda , Majdi Owda

Neural networks have been known for a long time as a tool for different types of classification, but only just in the last decade they have showed their entire power. Along with appearing of hardware that is capable to support demanding…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Marija Prokopijević , Aleksandar Stančić , Jelena Vasiljević , Željko Stojković , Goran Dimić , Jelena Sopta , Dalibor Ristić , Dhinaharan Nagamalai