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Medical experts often manually segment images to obtain diagnostic statistics and discard the resulting annotations. We aim to train segmentation models to alleviate this burden, but constrained to the retained summary statistics (e.g., the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Omkar Kulkarni , Edward Raff , Tim Oates

Prevention and early diagnosis of breast cancer (BC) is an essential prerequisite for the selection of proper treatment. The substantial pressure due to the increase of demand for faster and more precise diagnostic results drives for…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Peter Bokor , Lukas Hudec , Ondrej Fabian , Wanda Benesova

Acquiring sufficient ground-truth supervision to train deep visual models has been a bottleneck over the years due to the data-hungry nature of deep learning. This is exacerbated in some structured prediction tasks, such as semantic…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Xueyi Li , Tianfei Zhou , Jianwu Li , Yi Zhou , Zhaoxiang Zhang

Breast cancer diagnosis demands rapid and precise tools, yet traditional histopathological methods often fall short in intra-operative settings. Deep Ultraviolet (DUV) fluorescence imaging emerges as a transformative approach, offering…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nagur Shareef Shaik , Teja Krishna Cherukuri , Dong Hye Ye

Prostate cancer represents a major threat to health. Early detection is vital in reducing the mortality rate among prostate cancer patients. One approach involves using multi-modality (CT, MRI, US, etc.) computer-aided diagnosis (CAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Rui Jin , Derun Li , Dehui Xiang , Lei Zhang , Hailing Zhou , Fei Shi , Weifang Zhu , Jing Cai , Tao Peng , Xinjian Chen

In pathology, whole-slide images (WSI) based survival prediction has attracted increasing interest. However, given the large size of WSIs and the lack of pathologist annotations, extracting the prognostic information from WSIs remains a…

Image and Video Processing · Electrical Eng. & Systems 2021-10-25 Shuai Jiang , Arief A. Suriawinata , Saeed Hassanpour

The automatic registration of differently stained whole slide images (WSIs) is crucial for improving diagnosis and prognosis by fusing complementary information emerging from different visible structures. It is also useful to quickly…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Marek Wodzinski , Niccolò Marini , Manfredo Atzori , Henning Müller

Whole Slide Images (WSIs) play a crucial role in accurate cancer diagnosis and prognosis, as they provide tissue details at the cellular level. However, the rapid growth of computational tasks involving WSIs poses significant challenges.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Doanh C. Bui , Hoai Luan Pham , Vu Trung Duong Le , Tuan Hai Vu , Van Duy Tran , Khang Nguyen , Yasuhiko Nakashima

Reliable classification and detection of certain medical conditions, in images, with state-of-the-art semantic segmentation networks, require vast amounts of pixel-wise annotation. However, the public availability of such datasets is…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Erik Ostrowski , Bharath Srinivas Prabakaran , Muhammad Shafique

The performance of object detection, to a great extent, depends on the availability of large annotated datasets. To alleviate the annotation cost, the research community has explored a number of ways to exploit unlabeled or weakly labeled…

Computer Vision and Pattern Recognition · Computer Science 2021-05-25 Shijie Fang , Yuhang Cao , Xinjiang Wang , Kai Chen , Dahua Lin , Wayne Zhang

Weakly Supervised Semantic Segmentation (WSSS) techniques explore individual regularization strategies to refine Class Activation Maps (CAMs). In this work, we first analyze complementary WSSS techniques in the literature, their…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Lucas David , Helio Pedrini , Zanoni Dias

Text segmentation is a challenging vision task with many downstream applications. Current text segmentation methods require pixel-level annotations, which are expensive in the cost of human labor and limited in application scenarios. In…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Xinyan Zu , Haiyang Yu , Bin Li , Xiangyang Xue

The fine-grained annotations in whole slide images (WSIs) show the boundaries of various pathological regions. However, generating such detailed annotation is often costly, whereas the coarse annotations are relatively simpler to produce.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Bingjian Yao , Weiping Lin , Yan He , Zheng Wang , Liangsheng Wang

Molecular subtypes of breast cancer are important references to personalized clinical treatment. For cost and labor savings, only one of the patient's paraffin blocks is usually selected for subsequent immunohistochemistry (IHC) to obtain…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Hong Liu , Wen-Dong Xu , Zi-Hao Shang , Xiang-Dong Wang , Hai-Yan Zhou , Ke-Wen Ma , Huan Zhou , Jia-Lin Qi , Jia-Rui Jiang , Li-Lan Tan , Hui-Min Zeng , Hui-Juan Cai , Kuan-Song Wang , Yue-Liang Qian

Nuclei segmentation is one of the important tasks for whole slide image analysis in digital pathology. With the drastic advance of deep learning, recent deep networks have demonstrated successful performance of the nuclei segmentation task.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Inwan Yoo , Donggeun Yoo , Kyunghyun Paeng

Neural networks promise to bring robust, quantitative analysis to medical fields, but adoption is limited by the technicalities of training these networks. To address this translation gap between medical researchers and neural networks in…

Image and Video Processing · Electrical Eng. & Systems 2019-02-20 Brendon Lutnick , Brandon Ginley , Darshana Govind , Sean D. McGarry , Peter S. LaViolette , Rabi Yacoub , Sanjay Jain , John E. Tomaszewski , Kuang-Yu Jen , Pinaki Sarder

Compared to conventional semantic segmentation with pixel-level supervision, Weakly Supervised Semantic Segmentation (WSSS) with image-level labels poses the challenge that it always focuses on the most discriminative regions, resulting in…

Computer Vision and Pattern Recognition · Computer Science 2023-12-19 Jingxuan He , Lechao Cheng , Chaowei Fang , Zunlei Feng , Tingting Mu , Mingli Song

Multiple instance learning (MIL) has become a standard paradigm for the weakly supervised classification of whole slide images (WSIs). However, this paradigm relies on using a large number of labeled WSIs for training. The lack of training…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Minghao Han , Linhao Qu , Dingkang Yang , Xukun Zhang , Xiaoying Wang , Lihua Zhang

Specific and effective breast cancer therapy relies on the accurate quantification of PD-L1 positivity in tumors, which appears in the form of brown stainings in high resolution whole slide images (WSIs). However, the retrieval and…

Computational Engineering, Finance, and Science · Computer Science 2024-04-17 Giacomo Cignoni , Cristian Scatena , Chiara Frascarelli , Nicola Fusco , Antonio Giuseppe Naccarato , Giuseppe Nicoló Fanelli , Alina Sîrbu

Automatic surgical instrument segmentation of endoscopic images is a crucial building block of many computer-assistance applications for minimally invasive surgery. So far, state-of-the-art approaches completely rely on the availability of…

Computer Vision and Pattern Recognition · Computer Science 2022-02-17 Luca Sestini , Benoit Rosa , Elena De Momi , Giancarlo Ferrigno , Nicolas Padoy