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The mean first passage time (MFPT) for a Brownian particle to reach a small target in cellular microdomains is a key parameter for chemical activation. Although asymptotic estimations of the MFPT are available for various geometries, these…

Neurons and Cognition · Quantitative Biology 2015-03-19 Juergen Reingruber , David Holcman

Micro- and nano-swimmers moving in a fluid solvent confined by structures that produce entropic barriers are often described by overdamped active Brownian particle dynamics, where viscous effects are large and inertia plays no role.…

Soft Condensed Matter · Physics 2023-03-28 Narender Khatri , Raymond Kapral

In this paper we use singular perturbation theory to solve the 2D narrow capture problem for a set of partially accessible targets $\calU_k$, $k=1,\ldots,N$, in a bounded domain $\Omega\subset \R^2$. In contrast to previous models of narrow…

Statistical Mechanics · Physics 2025-04-08 Paul C Bressloff

We derive an analytical expression for the propagator and the transition path time distribution of a two-dimensional active Brownian particle crossing a parabolic barrier with absorbing boundary conditions at both sides. By taking those of…

Statistical Mechanics · Physics 2026-01-23 Michele Caraglio

Enhanced diffusion is an emergent property of many experimental microswimmer systems that usually arises from a combination of ballistic motion with random reorientations. A subset of these systems, autophoretic droplet swimmers that move…

Soft Condensed Matter · Physics 2022-11-17 Katherine Daftari , Katherine A. Newhall

We propose enforcing constraints on Model-Based Diffusion by introducing emerging barrier functions inspired by interior point methods. We demonstrate that the standard Model-Based Diffusion algorithm can lead to catastrophic performance…

Robotics · Computer Science 2026-03-10 Raghav Mishra , Ian R. Manchester

We investigate the ensemble and time averaged mean squared displacements for particle diffusion in a simple model for disordered media by assuming that the local diffusivity is both fluctuating in time and has a deterministic average growth…

Statistical Mechanics · Physics 2016-10-05 A. G. Cherstvy , R. Metzler

We study the first-passage-time (FPT) properties of active Brownian particles to reach an absorbing wall in two dimensions. Employing a perturbation approach we obtain exact analytical predictions for the survival and FPT distributions for…

Soft Condensed Matter · Physics 2025-03-10 Yanis Baouche , Magali Le Goff , Christina Kurzthaler , Thomas Franosch

We develop Random Batch Methods for interacting particle systems with large number of particles. These methods use small but random batches for particle interactions, thus the computational cost is reduced from $O(N^2)$ per time step to…

Numerical Analysis · Mathematics 2019-09-25 Shi Jin , Lei Li , Jian-Guo Liu

We study the narrow escape problem in the disk, which consists in identifying the first exit time and first exit point distribution of a Brownian particle from the ball in dimension 2, with reflecting boundary conditions except on small…

Analysis of PDEs · Mathematics 2024-04-09 Tony Lelièvre , Mohamad Rachid , Gabriel Stoltz

In this paper we analyze the narrow capture problem for a single Brownian particle diffusing in a three-dimensional (3D) bounded domain containing a set of small, spherical traps. The boundary surface of each trap is taken to be a…

Statistical Mechanics · Physics 2022-11-23 Paul C Bressloff

A new solution to the mono-dimensional diffusion equation for time-variable first kind boundary condition is presented where the time-variable function at the surface is derived proposing a surface saturation model. This solution may be…

Materials Science · Physics 2022-12-08 Guglielmo Macrelli

Let $Z$ be the transient reflecting Brownian motion on the closure of an unbounded domain $D\subset {\mathbb R}^d$ with $N$ number of Liouville branches. We consider a diffusion $X$ on $\overline D$ having finite lifetime obtained from $Z$…

Probability · Mathematics 2016-11-18 Zhen-Qing Chen , Masatoshi Fukushima

We construct and exactly solve a model of an extended Brownian ratchet. The model comprises an arbitrary number of heterogeneous, growing and shrinking filaments which together move a rigid membrane by a ratchet mechanism. The model draws…

Statistical Mechanics · Physics 2019-10-23 Anthony J. Wood , Richard A. Blythe , Martin R. Evans

We study a one-dimensional diffusion $X$ in a drifted Brownian potential $W\_\kappa$, with $ 0\textless{}\kappa\textless{}1$, and focus on the behavior of the local times $(\mathcal{L}(t,x),x)$ of $X$ before time $t\textgreater{}0$.In…

Probability · Mathematics 2016-09-08 Pierre Andreoletti , Alexis Devulder , Grégoire Vechambre

Barrier crossing is a widespread phenomenon across natural and engineering systems. While an abundant cross-disciplinary literature on the topic has emerged over the years, the stochastic underpinnings of the process are yet to be linked…

Statistical Mechanics · Physics 2024-12-19 Toby Kay , Luca Giuggioli

We introduce the stochastic process of incremental multifractional Brownian motion (IMFBM), which locally behaves like fractional Brownian motion with a given local Hurst exponent and diffusivity. When these parameters change as function of…

Statistical Mechanics · Physics 2023-07-27 Jakub Slezak , Ralf Metzler

Transport of particles through channels is of paramount importance in physics, chemistry and surface science due to its broad real world applications. Much insights can be gained by observing the transition paths of a particle through a…

Statistical Mechanics · Physics 2023-04-12 Siddharth Jain , Denis Boyer , Arnab Pal , Leonardo Dagdug

We prove the analogue for continuous space-time of the quenched LDP derived in Birkner, Greven and den Hollander (2010) for discrete space-time. In particular, we consider a random environment given by Brownian increments, cut into pieces…

Probability · Mathematics 2013-12-10 Matthias Birkner , Frank den Hollander

We treat the problem of particle pushing by growing ice as a free diffusion near a wall that moves with discrete steps. When the particle diffuse away from the surface the surface can grow, blocking the particle from going back. Elementary…

Soft Condensed Matter · Physics 2018-01-01 Michael Chasnitsky , Victor Yashunsky , Ido Braslavsky