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Structure determination is necessary to identify unknown organic molecules, such as those in natural products, forensic samples, the interstellar medium, and laboratory syntheses. Rotational spectroscopy enables structure determination by…

Machine Learning · Computer Science 2024-04-02 Austin Cheng , Alston Lo , Santiago Miret , Brooks Pate , Alán Aspuru-Guzik

We investigate the structures of the near-plate velocity and temperature profiles at different horizontal positions along the conducting bottom (and top) plate of a Rayleigh-B\'{e}nard convection cell, using two-dimensional (2D) numerical…

In this paper, we propose a tumor growth model to incorporate and investigate the spatial effects of autophagy. The cells are classified into two phases: normal cells and autophagic cells, whose dynamics are also coupled with the nutrients.…

Analysis of PDEs · Mathematics 2021-08-31 Xu'an Dou , Jian-Guo Liu , Zhennan Zhou

This paper presents an analysis of the orientation selectivity properties of idealized models of complex cells in terms of affine quasi quadrature measures, which combine the responses of idealized models of simple cells in terms of affine…

Neurons and Cognition · Quantitative Biology 2025-08-26 Tony Lindeberg

Graph-based representation approaches have been proven to be successful in the analysis of biomedical data, due to their capability of capturing intricate dependencies between biological entities, such as the spatial organization of…

Machine Learning · Computer Science 2023-10-11 Manuel Madeira , Dorina Thanou , Pascal Frossard

Biological foundation models have shown strong performance in single-cell representation learning by applying transformer architectures directly to gene-expression matrices. However, these approaches predominantly operate in static settings…

Machine Learning · Computer Science 2026-05-28 Manuel Dileo , Andrea Sottoriva

Owing to the recent, rapid development of computer technology, the resolution of atmospheric numerical models has increased substantially. With the use of next-generation supercomputers, atmospheric simulations using horizontal grid…

Numerical Analysis · Mathematics 2016-05-25 H. Yamazaki , T. Satomura , N. Nikiforakis

We develop a polycrystal graph neural network (PGNN) model for predicting the effective properties of polycrystalline materials, using the Li7La3Zr2O12 ceramic as an example. A large-scale dataset with >5000 different three-dimensional…

Materials Science · Physics 2023-06-09 Minyi Dai , Mehmet F. Demirel , Xuanhan Liu , Yingyu Liang , Jia-Mian Hu

3D Geometric Graph Neural Networks (GNNs) have emerged as transformative tools for modeling molecular data. Despite their predictive power, these models often suffer from limited interpretability, raising concerns for scientific…

Machine Learning · Computer Science 2025-05-06 Jingxiang Qu , Wenhan Gao , Jiaxing Zhang , Xufeng Liu , Hua Wei , Haibin Ling , Yi Liu

Biological systems exhibit processes on a wide range of time and length scales. This work demonstrates that models, wherein the interaction between system constituents is captured by algebraic operations, inherently allow for successive…

Molecular Networks · Quantitative Biology 2019-08-16 Dimitri Loutchko

Hydrocarbon pyrolysis is a complex process involving large numbers of chemical species and types of chemical reactions. Its quantitative description is important for planetary sciences, in particular, for understanding the processes…

Atomic and Molecular Clusters · Physics 2022-09-09 Vincent Dufour-Décieux , Christopher Moakler , Maria Cameron , Evan J. Reed

In this paper we consider the fundamental problem of approximating the diameter $D$ of directed or undirected graphs. In a seminal paper, Aingworth, Chekuri, Indyk and Motwani [SIAM J. Comput. 1999] presented an algorithm that computes in…

Data Structures and Algorithms · Computer Science 2012-07-17 Liam Roditty , Virginia Vassilevska Williams

Graph neural networks (GNN) are very popular methods in machine learning and have been applied very successfully to the prediction of the properties of molecules and materials. First-order GNNs are well known to be incomplete, i.e., there…

Machine Learning · Statistics 2022-11-08 Sergey N. Pozdnyakov , Michele Ceriotti

The acid-mediated tumor invasion hypothesis proposes that altered glucose metabolism exhibited by the vast majority of tumors leads to increased acid (H+ ion) production which subsequently facilitates tumor invasion [1-3]. The…

Tissues and Organs · Quantitative Biology 2019-06-10 Ahmed M. Fouad

In this work, we present a computational analysis of the planar wave propagation behavior of a one-dimensional periodic multi-stable cellular material. Wave propagation in these materials is interesting because they combine the ability of…

Applied Physics · Physics 2019-11-19 Camilo Valencia , David Restrepo , Nilesh D. mankame , Pablo D. Zavattieri , Juan Gomez

Steady-state pair correlations between inelastic granular beads in a vertically shaken, quasi two-dimensional cell can be mapped onto the particle correlations in a truly two-dimensional reference fluid in thermodynamic equilibrium. Using…

Soft Condensed Matter · Physics 2019-06-12 Gustavo M. Rodríguez-Liñán , Marco Heinen

We study spectra of alloy-type random Schr\"odinger operators on metric graphs. For finite edge subsets of general graphs we prove a Wegner estimate which is linear in the volume (i.e. the number of edges) and the length of the considered…

Spectral Theory · Mathematics 2009-11-11 Mario Helm , Ivan Veselic'

Physical systems with complex unsteady dynamics, such as fluid flows, are often poorly represented by a single mean solution. For many practical applications, it is crucial to access the full distribution of possible states, from which…

Computational Physics · Physics 2025-04-07 Mario Lino , Tobias Pfaff , Nils Thuerey

The complexity of gene regulatory networks in multicellular organisms makes interpretable low-dimensional models highly desirable. An attractive geometric picture, attributed to Waddington, visualizes the differentiation of a cell into…

Biological Physics · Physics 2024-12-12 Gautam Reddy

A molecule's 2D representation consists of its atoms, their attributes, and the molecule's covalent bonds. A 3D (geometric) representation of a molecule is called a conformer and consists of its atom types and Cartesian coordinates. Every…