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Context. Adaptive optics (AO) is now a tool commonly deployed in astronomy. The real time correction of the atmospheric turbulence that AO enables allows telescopes to perform close to the diffraction limit at the core of their point spread…

Instrumentation and Methods for Astrophysics · Physics 2023-06-21 Anthony Berdeu , Michel Tallon , Éric Thiébaut , Maud Langlois

Microaneurysms (MAs) are one of the earliest signs of diabetic retinopathy (DR), a frequent complication of diabetes that can lead to visual impairment and blindness. Adaptive optics scanning laser ophthalmoscopy (AOSLO) provides real-time…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Qian Zhang , Konstantina Sampani , Mengjia Xu , Shengze Cai , Yixiang Deng , He Li , Jennifer K. Sun , George Em Karniadakis

Nano-optic imagers that modulate light at sub-wavelength scales could unlock unprecedented applications in diverse domains ranging from robotics to medicine. Although metasurface optics offer a path to such ultra-small imagers, existing…

Artificial neural networks (ANNs) have now been widely used for industry applications and also played more important roles in fundamental researches. Although most ANN hardware systems are electronically based, optical implementation is…

Widefield microscopy is widely used for non-invasive imaging of biological structures at subcellular resolution. When applied to complex specimen, its image quality is degraded by sample-induced optical aberration. Adaptive optics can…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Iksung Kang , Qinrong Zhang , Stella X. Yu , Na Ji

Imaging through complex scattering media is severely limited by aberrations and scattering which obscure images and reduce resolution. Confocal and temporal gatings partly filter out multiple scattering but are severely degraded by…

Optics · Physics 2026-05-18 Yiwen Zhang , Minh Dinh , Zeyu Wang , Tianhao Zhang , Tianhang Chen , Chia Wei Hsu

Due to turbulence in the atmosphere images taken from ground-based telescopes become distorted. With adaptive optics (AO) images can be given greater clarity allowing for better observations with existing telescopes and are essential for…

Instrumentation and Methods for Astrophysics · Physics 2023-08-30 Javier Perez Soto , Cesar Laguna , Benjamin L. Gerard , Anne Dattilo , Vincent Chambouleyron , Rebecca Jensen-Clem

High-contrast imaging systems using active control with adaptive optics (AO) are often limited by non-common path (NCP) aberrations that are seen only at the final science image. AO systems employing focal-plane wavefront sensors (FP-WFSs)…

Instrumentation and Methods for Astrophysics · Physics 2026-01-22 Aditya R. Sengupta , Lisa A. Poyneer , Benjamin L. Gerard , Rebecca Jensen-Clem , Aaron J. Lemmer

Deformable image registration is fundamental for many medical image analyses. A key obstacle for accurate image registration lies in image appearance variations such as the variations in texture, intensities, and noise. These variations are…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Mingyuan Meng , Lei Bi , Michael Fulham , David Dagan Feng , Jinman Kim

Unsupervised anomaly detection aims to build models to effectively detect unseen anomalies by only training on the normal data. Although previous reconstruction-based methods have made fruitful progress, their generalization ability is…

Machine Learning · Computer Science 2022-01-04 Yuxin Zhang , Jindong Wang , Yiqiang Chen , Han Yu , Tao Qin

Ultra-thin multimode optical fiber imaging promises next-generation medical endoscopes reaching high image resolution for deep tissues. However, current technology suffers from severe optical distortion, as the fiber's calibration is…

Optics · Physics 2023-10-04 Yijie Zheng , George S. D. Gordon

We develop a novel optical neural network (ONN) framework which introduces a degree of scalar invariance to image classification estima- tion. Taking a hint from the human eye, which has higher resolution near the center of the retina,…

Computer Vision and Pattern Recognition · Computer Science 2018-05-30 Grant Fennessy , Yevgeniy Vorobeychik

Multi-object adaptive optics (MOAO) has been demonstrated by the CANARY instrument on the William Herschel Telescope. However, for proposed MOAO systems on the next generation Extremely Large Telescopes, such as EAGLE, many challenges…

Instrumentation and Methods for Astrophysics · Physics 2015-06-16 A. G. Basden , N. A. Bharmal , R. M. Myers , S. L. Morris , T. J. Morris

Acousto-optic imaging (AOI) enables optical-contrast imaging deep inside scattering samples via localized ultrasound-modulation of scattered light. While AOI allows optical investigations at depths, its imaging resolution is inherently…

Optics · Physics 2021-01-26 Moriya Rosenfeld , Daniel Doktofsky , Gil Weinberg , Yunzhe Li , Lei Tian , Ori Katz

Inverse medium scattering is an ill-posed, nonlinear wave-based imaging problem arising in medical imaging, remote sensing, and non-destructive testing. Machine learning (ML) methods offer increased inference speed and flexibility in…

Computational Physics · Physics 2025-12-12 Olivia Tsang , Owen Melia , Vasileios Charisopoulos , Jeremy Hoskins , Yuehaw Khoo , Rebecca Willett

As we read this text, our eyes dynamically adjust the focal length to keep the line image in focus on the retina. Similarly, in many optics applications the focal length must be dynamically tunable. In the quest for compactness and…

Diffractive optical neural networks (DONNs) have been emerging as a high-throughput and energy-efficient hardware platform to perform all-optical machine learning (ML) in machine vision systems. However, the current demonstrated…

Machine Learning · Computer Science 2023-02-23 Ruiyang Chen , Yingheng Tang , Jianzhu Ma , Weilu Gao

A unique sample independent 3D self calibration methodology is tested on a unique optical coherence tomography and multi-spectral scanning laser ophthalmoscope (OCT-SLO) hybrid system. Operators visual cognition is replaced by computer…

Medical Physics · Physics 2024-08-08 Mayank Goswami

Confocal Raman microscopy, a highly specific and label-free technique for the microscale study of thick samples, often presents difficulties due to weak Raman signals. Inhomogeneous samples introduce wavefront aberrations that further…

Vectorial adaptive optics (V-AO) is a cutting-edge technique extending conventional AO into the vectorial domain encompassing both polarization and phase feedback correction for optical systems. However, previous V-AO approaches focus on…

Optics · Physics 2023-12-12 Yifei Ma , Zimo Zhao , Jiahe Cui , Jingyu Wang , Chao He