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Imaging dynamical processes at interfaces and on the nanoscale is of great importance throughout science and technology. While light-optical imaging techniques often cannot provide the necessary spatial resolution, electron-optical…

The ability to spatially and temporally map nanoscale environments in situ over extended timescales would be transformative for biology, biomedicine, and bioengineering. All nanometer objects, from nanoparticles down to single proteins,…

Optics · Physics 2023-10-04 Guangjie Cui , Do Young Kim , Di Zu , Guanbo Chai , Somin Eunice Lee

One of the most important tools in modern science is the analysis of electromagnetic properties via spectroscopy. The various types of spectroscopy can be classified by the underlying type of interactions between energy and material. In…

Optics · Physics 2020-01-22 Johannes Fiedler , Clas Persson , Stefan Yoshi Buhmann

Recent advancements in nanotechnology have led to the development of surface-enhanced Raman spectroscopy (SERS) based rapid and low-cost technologies for ultra-sensitive label-free detection and identification of molecular analytes. Herein,…

Histochemical staining is essential for visualizing tissue architecture and cellular morphology but is destructive and limited by the availability of tissue for multiple stains. Virtual staining with label-free microscopy offers a…

Single molecule detection provides detailed information about molecular structures and functions, but it generally requires the presence of a fluorescent marker which can interfere with the activity of the target molecule or complicate the…

Detecting clinically relevant objects in medical images is a challenge despite large datasets due to the lack of detailed labels. To address the label issue, we utilize the scene-level labels with a detection architecture that incorporates…

Computer Vision and Pattern Recognition · Computer Science 2020-08-03 Leo K. Tam , Xiaosong Wang , Evrim Turkbey , Kevin Lu , Yuhong Wen , Daguang Xu

This paper introduces current watermarking techniques available from the literatures. Requirements for medical watermarking will be discussed. We then propose a watermarking scheme that can recover the original image from the watermarked…

Cryptography and Security · Computer Science 2011-01-11 Jasni Mohamad Zain , Malcolm Clarke

Optical-based nanothermometry represents a transformative approach for precise temperature measurements at the nanoscale, which finds versatile applications across biology, medicine, and electronics. The assembly of ratiometric fluorescent…

Optics · Physics 2025-04-01 Mahshid Iraniparast , Nishant Kumar , Igor Sokolov

Inverse scattering problems without the phase information arise in imaging of nanostructures whose sizes are hundreds of nanometers as well as in imaging of biological cells. The governing equation is the 3-d generalized Helmholtz equation…

Analysis of PDEs · Mathematics 2015-10-05 Michael V. Klibanov , Loc H. Nguyen , Kejia Pan

Fine-grained attribute prediction is essential for fashion retail applications including catalog enrichment, visual search, and recommendation systems. Vision-Language Models (VLMs) offer zero-shot prediction without task-specific training,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shubham Shukla , Kunal Sonalkar

We introduce a new image cytometer design for detection of very small particulate and demonstrate its capability in water analysis. The device is a compact microscope composed of off the shelf components, such as a light emitting diode…

Optics · Physics 2016-02-17 Juan Miguel Pérez , Marc Jofre , Pedro Martínez , Valerio Pruneri

Surface-functionalized nanomaterials can act as theranostic agents that detect disease and track biological processes using hyperpolarized magnetic resonance imaging (MRI). Candidate materials are sparse however, requiring spinful nuclei…

Labelfree nanoscopy encompasses optical imaging with resolution in the 100 nm range using visible wavelengths. Here, we present a labelfree nanoscopy method that combines Fourier ptychography with waveguide microscopy to realize a…

We theoretically study non-destructive detection of ultracold molecules, using a Fabry-Perot cavity. Specifically, we consider vacuum Rabi splitting where we demonstrate the use of collective strong coupling for detection of molecules with…

Quantum Physics · Physics 2018-06-20 Rahul Sawant , Olivier Dulieu , S. A. Rangwala

Physicochemical characterization of materials is central to the field of science and engineering and is essential to design new/engineered materials with specific properties. Assays available for small-molecules, e.g., XRD, NMR, LC-MS,…

Nanophotonics, the study of light-matter interaction at scales smaller than the wavelength of radiation, has widespread applications in plasmonic waveguiding, topological photonic crystals, super-lensing, solar absorbers, and infrared…

Optics · Physics 2024-09-23 Sathwik Bharadwaj , Zubin Jacob

Nanoimprint lithography (NIL) is a widely used high-throughput fabrication technique for photonic devices, yet its reliability is often compromised by the inevitable imperfections that arise during the demolding process. Topological…

We present a rapid and stain-free quantitative viral plaque assay using lensfree holographic imaging and deep learning. This cost-effective, compact, and automated device significantly reduces the incubation time needed for traditional…

Accurately measuring the size, morphology, and structure of nanoparticles is very important, because they are strongly dependent on their properties for many applications. In this paper, we present a deep-learning based method for…

Materials Science · Physics 2022-07-29 Claudius Zelenka , Marius Kamp , Kolja Strohm , Akram Kadoura , Jacob Johny , Reinhard Koch , Lorenz Kienle