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Biological cells are able to generate intricate structures and respond to external stimuli, sculpting their membrane from within. Simplified biomimetic systems can aid in understanding the principles which govern these shape changes and…

Thin cylindrical tethers are common lipid bilayer membrane structures, arising in situations ranging from micromanipulation experiments on artificial vesicles to the dynamic structure of the Golgi apparatus. We study the shape and formation…

Soft Condensed Matter · Physics 2009-11-07 Thomas R. Powers , Greg Huber , Raymond E. Goldstein

The presence of membrane tubules in living cells is essential to many biological processes. In cells, one mechanism to form nanosized lipid tubules is via molecular motor induced bilayer extraction. In this paper, we describe a simple…

Biomolecules · Quantitative Biology 2016-10-04 Chai Lor , Joseph D. Lopes , Michelle K. Mattson-Hoss , Jing Xu , Linda S. Hirst

In hydrodynamic descriptions of lipid bilayers, the membrane is often approximated as being impermeable to the surrounding, solute-containing fluid. However, biological and in vitro lipid membranes are influenced by their permeability and…

Soft Condensed Matter · Physics 2026-02-24 Amaresh Sahu

We study the effect of permeabilizing electric fields applied to two different types of giant unilamellar vesicles, the first formed from EggPC lipids and the second formed from DOPC lipids. Experiments on vesicles of both lipid types show…

Soft Condensed Matter · Physics 2011-02-04 T. Portet , F. Camps i Febrer , J. -M. Escoffre , C. Favard , M. -P. Rols , D. S. Dean

The motion of flexible fibers through structured fluidic environments is ubiquitous in nature and industrial applications. Most often, their dynamics results from the complex interplay between internal elastic stresses, contact forces and…

Fluid Dynamics · Physics 2022-09-23 Ursy Makanga , Mohammadreza Sepahi , Camille Duprat , Blaise Delmotte

The interpretation electrical phenomena in biomembranes is usually based on the assumption that the experimentally found discrete ion conduction events are due to a particular class of proteins called ion channels while the lipid membrane…

Biological Physics · Physics 2010-06-17 Thomas Heimburg

We grafted polyacrylic acid brushes containing cysteine side chains at a defined surface density on planar lipid membranes. Specular X-ray reflectivity data indicated that the addition of Cd2+ ions induces the compaction of the polymer…

Soft Condensed Matter · Physics 2022-03-29 Felix Weissenfeld , Lucia Wesenberg , Masaki Nakahata , Marcus Müller , Motomu Tanaka

Formation and rupture of vesicles is a fundamental process underlying diverse phenomena in biology, materials science, and biomedical applications. Vesicles form when the area of a growing disk-like membrane exceeds a critical value at…

Soft Condensed Matter · Physics 2025-11-11 Seungwoo Shin , Federico Cao , Robert A. Pelcovits , Thomas R. Powers , Zvonimir Dogic

Microflows are intensively used for investigating and controlling the dynamics of particles, including soft particles such as biological cells and capsules. A classic result is the tank-treading motion of elliptically deformed soft…

Soft Condensed Matter · Physics 2021-10-06 Matthias Laumann , Walter Zimmermann

Advances in nanotechnology lead to an increasing interest in how nanoparticles interact with biomembranes. Nanoparticles are wrapped spontaneously by biomembranes if the adhesive interactions between the particles and membranes compensate…

Subcellular Processes · Quantitative Biology 2016-09-16 Michael Raatz , Thomas R. Weikl

Membrane budding has been extensively studied as an equilibrium process attributed to the formation of coexisting domains or changes in the vesicle area to volume ratio (reduced volume). In contrast, non-equilibrium budding remains…

Biological Physics · Physics 2013-03-27 Thomas Franke , Christian T. Leirer , Achim Wixforth , Nily Dan , Matthias F. Schneider

We present direct experimental evidence that water droplets can spontaneously penetrate non-wetting capillaries, driven by the action of Laplace pressure due to high droplet curvature. Using high-speed optical imaging, microcapillaries of…

Fluid Dynamics · Physics 2010-02-04 Geoff R. Willmott , Chiara Neto , Shaun C. Hendy

Soft particles display highly versatile properties with respect to hard colloids, even more so at fluid-fluid interfaces. In particular, microgels, consisting of a cross-linked polymer network, are able to deform and flatten upon adsorption…

Recent experiments have shown that when a near-hemispherical lipid vesicle attached to a solid surface is subjected to a simple shear flow it exhibits a pattern of membrane circulation much like a dipole vortex. This is in marked contrast…

Fluid Dynamics · Physics 2012-08-14 Francis G. Woodhouse , Raymond E. Goldstein

On the basis of the separated form-factors model, parameters of the polydispersed unilamellar DMPC vesicle population are analyzed. The neutron scattering length density across the membrane is simulated on the basis of fluctuated model of…

Biological Physics · Physics 2007-05-23 M. A. Kiselev , E. V. Zemlyanaya , V. K. Aswal

For many viruses assembly and budding occur simultaneously during virion formation. Understanding the mechanisms underlying this process could promote biomedical efforts to block viral propagation and enable use of capsids in nanomaterials…

Subcellular Processes · Quantitative Biology 2014-03-11 Teresa Ruiz-Herrero , Michael F. Hagan

Giant unilamellar vesicles (GUVs) composed of as few as three lipid species can phase separate into small-scale lipid domains with stripes and dots patterns. These patterns have been experimentally characterized in terms of how their size…

Soft Condensed Matter · Physics 2025-05-21 Qiwei Yu , Andrej Košmrlj

Manipulating particles, such as cells and tissues, in a flowing liquid environment is crucial for life science research. Traditional contactless tweezers, although widely used for single-cell manipulation, face several challenges. These…

Fluid Dynamics · Physics 2025-01-07 Yuhong Zhou , Fubao Yang , Jinrong Liu , Gaole Dai , Zixin Li , Xuzhi Zhou , Peng Jin , Jiping Huang

We study the interaction of small hydrophobic particles on the surface of an ultra-soft elastic gel, in which a small amount of elasticity of the medium balances the weights of the particles. The excess energy of the surface of the deformed…

Soft Condensed Matter · Physics 2014-06-09 Aditi Chakrabarti , Manoj K. Chaudhury
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