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Simultaneous variable selection and statistical inference is challenging in high-dimensional data analysis. Most existing post-selection inference methods require explicitly specified regression models, which are often linear, as well as…

Methodology · Statistics 2026-03-19 Shangyuan Ye , Shauna Rakshe , Ye Liang

Sufficient dimension reduction aims for reduction of dimensionality of a regression without loss of information by replacing the original predictor with its lower-dimensional subspace. Partial (sufficient) dimension reduction arises when…

Methodology · Statistics 2019-09-27 Lu Li , Kai Tan , Xuerong Meggie Wen , Zhou Yu

Identifying low-dimensional sufficient structures in nonlinear sufficient dimension reduction (SDR) has long been a fundamental yet challenging problem. Most existing methods lack theoretical guarantees of exhaustiveness in identifying…

Machine Learning · Statistics 2025-12-23 Shuntuo Xu , Zhou Yu , Jian Huang

Causal inference has received great attention across different fields from economics, statistics, education, medicine, to machine learning. Within this area, inferring causal effects at individual level in observational studies has become…

Methodology · Statistics 2017-02-16 Thai Pham

Contrastive dimension reduction (CDR) methods aim to extract signal unique to or enriched in a treatment (foreground) group relative to a control (background) group. This setting arises in many scientific domains, such as genomics, imaging,…

Methodology · Statistics 2025-10-15 Sam Hawke , Eric Zhang , Jiawen Chen , Didong Li

Dimension reduction lies at the heart of many statistical methods. In regression, dimension reduction has been linked to the notion of sufficiency whereby the relation of the response to a set of predictors is explained by a lower…

Methodology · Statistics 2020-06-02 Hyung Park , Eva Petkova , Thaddeus Tarpey , R. Todd Ogden

Dimension reduction is often the first step in statistical modeling or prediction of multivariate spatial data. However, most existing dimension reduction techniques do not account for the spatial correlation between observations and do not…

Methodology · Statistics 2025-05-27 Si Cheng , Magali N. Blanco , Timothy V. Larson , Lianne Sheppard , Adam Szpiro , Ali Shojaie

When estimating the treatment effect in an observational study, we use a semiparametric locally efficient dimension reduction approach to assess both the treatment assignment mechanism and the average responses in both treated and…

Methodology · Statistics 2020-10-26 Trinetri Ghosh , Yanyuan Ma , Xavier de Luna

The principal support vector machines method (Li et al., 2011) is a powerful tool for sufficient dimension reduction that replaces original predictors with their low-dimensional linear combinations without loss of information. However, the…

Machine Learning · Statistics 2019-12-02 Jun Jin , Chao Ying , Zhou Yu

Sufficient dimension reduction [J. Amer. Statist. Assoc. 86 (1991) 316-342] has long been a prominent issue in multivariate nonparametric regression analysis. To uncover the central dimension reduction space, we propose in this paper an…

Statistics Theory · Mathematics 2014-08-15 Efang Kong , Yingcun Xia

Sufficient dimension reduction is a powerful tool to extract core information hidden in the high-dimensional data and has potentially many important applications in machine learning tasks. However, the existing nonlinear sufficient…

Machine Learning · Computer Science 2022-10-11 Siqi Liang , Yan Sun , Faming Liang

Identifying relationships between molecular variations and their clinical presentations has been challenged by the heterogeneous causes of a disease. It is imperative to unveil the relationship between the high dimensional molecular…

Methodology · Statistics 2021-09-02 Wennan Chang , Changlin Wan , Yong Zang , Chi Zhang , Sha Cao

In this work, we consider causal inference in various high-dimensional treatment settings, including for single multi-valued treatments and vector treatments with binary or continuous components, when the number of treatments can be…

Statistics Theory · Mathematics 2026-02-26 Patrick Kramer , Edward H. Kennedy , Isaac M. Opper

High-dimensional compositional data, such as those from human microbiome studies, pose unique statistical challenges due to the simplex constraint and excess zeros. While dimension reduction is indispensable for analyzing such data,…

Methodology · Statistics 2025-09-09 Junyoung Park , Cheolwoo Park , Jeongyoun Ahn

We address the problem of estimating causal effects from observational data in the presence of network confounding, a setting where both treatment assignment and observed outcomes of individuals may be influenced by their neighbors within a…

Machine Learning · Computer Science 2026-03-24 Abhishek Dalvi , Neil Ashtekar , Vasant Honavar

Many machine learning applications deal with high dimensional data. To make computations feasible and learning more efficient, it is often desirable to reduce the dimensionality of the input variables by finding linear combinations of the…

Machine Learning · Computer Science 2025-01-30 Wenjing Yang , Yuhong Yang

Popularly used eigendecomposition-based criteria such as BIC type, ratio estimation and principal component-based criterion often underdetermine model dimensionality for regressions or the number of factors for factor models. This…

Statistics Theory · Mathematics 2016-08-17 Xuehu Zhu , Tao Wang , Lixing Zhu

The foremost challenge to causal inference with real-world data is to handle the imbalance in the covariates with respect to different treatment options, caused by treatment selection bias. To address this issue, recent literature has…

Machine Learning · Statistics 2022-02-23 Zhixuan Chu , Stephen Rathbun , Sheng Li

Researchers in the biological sciences nowadays often encounter the curse of high-dimensionality, which many previously developed statistical models fail to overcome. To tackle this problem, sufficient dimension reduction aims to estimate…

Methodology · Statistics 2012-03-19 Hung Hung

We introduce a novel sufficient dimension-reduction (SDR) method which is robust against outliers using $\alpha$-distance covariance (dCov) in dimension-reduction problems. Under very mild conditions on the predictors, the central subspace…

Methodology · Statistics 2024-02-06 Hsin-Hsiung Huang , Feng Yu , Teng Zhang