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We study transport in synthetic, bi-disperse porous structures, with arrays of microchannels interconnected by a nanoporous layer. These structures are inspired by the xylem tissue in vascular plants, in which sap water travels from the…

Soft Condensed Matter · Physics 2024-07-23 Olivier Vincent , Théo Tassin , Erik J. Huber , Abraham D. Stroock

Myosin motor proteins drive vigorous steady-state fluctuations in the actin cytoskeleton of cells. Endogenous embedded semiflexible filaments such as microtubules, or added filaments such as single-walled carbon nanotubes are used as novel…

Biological Physics · Physics 2016-06-21 J. Gladrow , N. Fakhri , F. C. MacKintosh , C. F. Schmidt , C. P. Broedersz

The diffusion of a system of ferromagnetic dipoles confined in a quasi-one-dimensional parabolic trap is studied using Brownian dynamics simulations. We show that the dynamics of the system is tunable by an in-plane external homogeneous…

Soft Condensed Matter · Physics 2013-01-15 D. Lucena , W. P. Ferreira , F. F. Munarin , G. A. Farias , F. M. Peeters

The traffic of molecular motors through open tube-like compartments is studied using lattice models. These models exhibit boundary-induced phase transitions related to those of the asymmetric simple exclusion process (ASEP) in one…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Reinhard Lipowsky

The interaction between actin filaments and microtubules is crucial for many eukaryotic cellular processes, such as, among others, cell polarization, cell motility and cellular wound healing. The importance of this interaction has long been…

Subcellular Processes · Quantitative Biology 2020-09-28 Marco Saltini , Bela M. Mulder

Combined diverse two-dimensional (2D) materials for semiconductor interfaces are attractive for electrically controllable carrier confinement to enable excellent electrostatic control. We investigated the transport characteristic in…

Mesoscale and Nanoscale Physics · Physics 2021-03-22 Rahul Tripathi , Pritam Bhattacharyya , Sukanta Nandi , Alok Shukla , Abha Misra

We introduce the totally asymmetric exclusion process with Langmuir kinetics (TASEP-LK) on a network as a microscopic model for active motor protein transport on the cytoskeleton, immersed in the diffusive cytoplasm. We discuss how the…

Statistical Mechanics · Physics 2013-03-01 I. Neri , N. Kern , A. Parmeggiani

Microtubules (MTs) represent basic components of a cytoskeleton. The present work studies nonlinear dynamics of MTs assuming tangential oscillations of the dimers. We introduce a two component model and show that the dynamics of MTs can be…

Biological Physics · Physics 2023-02-06 Slobodan Zdravković , Slobodan Zeković

Many living and physical systems such as cell aggregates, tissues or bacterial colonies behave as unconventional systems of particles that are strongly constrained by volume exclusion and shape interactions. Understanding how these…

Quantitative Methods · Quantitative Biology 2026-05-20 Antoine Diez , Jean Feydy

Molybdenum disulfide is considered as one of the most promising two-dimensional semiconductors for electronic and optoelectronic device applications. So far, the charge transport in monolayer molybdenum disulfide is dominated by extrinsic…

Active transport of biomolecules assisted by motor proteins is imperative for the proper functioning of cellular activities. Inspired by the diffusion of active agents in crowded cellular channels, we computationally investigate the…

Soft Condensed Matter · Physics 2022-01-19 Rajiblochan Sahoo , Ligesh Theeyancheri , Rajarshi Chakrabarti

Here we generalize our previous model of molecular motors trafficking subdiffusing cargos in viscoelastic cytosol by (i) including mechanochemical coupling between cyclic conformational fluctuations of the motor protein driven by the…

Biological Physics · Physics 2015-05-01 Igor Goychuk

We introduce a multi-species lattice gas model for motor protein driven collective cargo transport on cellular filaments. We use this model to describe and analyze the collective motion of interacting vesicle cargoes being carried by…

Statistical Mechanics · Physics 2010-09-10 Sudipto Muhuri , Ignacio Pagonabarraga

All materials enter or exit the cell nucleus through nuclear pore complexes (NPCs), efficient transport devices that combine high selectivity and throughput. A central feature of this transport is the binding of cargo-carrying soluble…

Cell Behavior · Quantitative Biology 2015-06-26 A. Zilman , S. DiTalia , B. T. Chait , M. P Rout , M. O. Magnasco

The motility of eukaryotic cells is strongly influenced by their environment, with confined cells often developing qualitatively different motility patterns from those migrating on simple two-dimensional substrates. Recent experiments,…

Cell Behavior · Quantitative Biology 2024-12-24 Pedrom Zadeh , Brian A. Camley

The microtubule is a cylindrical biological polymer that plays key roles in cellular structure, transport, and signalling. In this work, based on studies of electronic properties of polyacetelene and mechanical properties of microtubules…

Mesoscale and Nanoscale Physics · Physics 2023-08-22 Varsha Subramanyan , Kay L. Kirkpatrick , Saraswathi Vishveshwara , Smitha Vishveshwara

During migration cells exhibit a rich variety of seemingly random migration patterns, which makes unraveling the underlying mechanisms that control cell migration a daunting challenge. For efficient migration cells require a mechanism for…

Biological Physics · Physics 2020-08-19 Jonathan E. Ron , Pascale Monzo , Nils Gauthier , Raphael Voituriez , Nir S. Gov

The flow of motor proteins on a filamental track is modelled within the the framework of lattice driven diffusive systems. Motors, considered as hopping particles, perform a highly biased asymmetric exclusion process when bound to the…

Statistical Mechanics · Physics 2007-05-23 M. Ebrahim Fouladvand , Modjtaba Salehi , Mostafa Yadegari

The cytoskeleton is a model active matter system that controls diverse cellular processes from division to motility. While both active actomyosin dynamics and actin-microtubule interactions are key to the cytoskeleton's versatility and…

Cells control fluid flows with a spatial and temporal precision that far exceeds the capabilities of current microfluidic technologies. Cells achieve this superior spatio-temporal control by harnessing dynamic networks of cytoskeleton and…

Soft Condensed Matter · Physics 2025-05-26 Fan Yang , Shichen Liu , Heun Jin Lee , Rob Phillips , Matt Thomson