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We focus on potential mechanisms for `energy-loss-free' transport along the cell microtubules, which could be considered as realizations of Fr\"ohlich's ideas on the role of solitons for superconductivity and/or biological matter. In…

Quantum Physics · Physics 2007-05-23 N. E. Mavromatos , D. V. Nanopoulos

Molecular motors play pivotal roles in organizing the interior of cells. A motor efficient in cargo transport would move along cytoskeletal filaments with a high speed and a minimal error in transport distance (or time) while consuming a…

Biological Physics · Physics 2019-06-07 Wonseok Hwang , Changbong Hyeon

Microtubules (MTs) nucleated by centrosomes form star-shaped structures referred to as asters. Aster motility and dynamics is vital for genome stability, cell division, polarization and differentiation. Asters move either towards the cell…

Subcellular Processes · Quantitative Biology 2019-05-21 Chaitanya A. Athale , Ana Dinarina , Francois Nedelec , Eric Karsenti

In this paper, we introduce an ASEP-like transport model for bidirectional motion of particles on a multi-lane lattice. The model is motivated by {\em in vivo} experiments on organelle motility along a microtubule (MT), consisting of…

Cellular Automata and Lattice Gases · Physics 2015-05-28 Congping Lin , Gero Steinberg , Peter Ashwin

Gate-controllable two dimensional systems with in-plane modulation of properties could serve as highly tunable effective media. Intuitively, such systems may bring novel functionality provided that the period of the lateral modulation is…

Mesoscale and Nanoscale Physics · Physics 2019-11-04 Alexey Shupletsov , Alexander Kuntsevich , Martin Nunuparov , Alexander Rakhmanov , Kirill Prikhodko

This paper presents a symmetric unified transport (UT) compact model for metal-oxide-semiconductor field-effect transistors (MOSFETs) that bridges drift-diffusion (DD) and ballistic transport (BT) regimes. The proposed model self…

Mesoscale and Nanoscale Physics · Physics 2026-05-27 Chien-Ting Tung

Within living cells, the transport of cargo is accomplished by groups of molecular motors. Such collective transport could utilize mechanisms which emerge from inter-motor interactions in ways that are yet to be fully understood. Here we…

Biomolecules · Quantitative Biology 2016-10-04 David Ando , Michelle K. Mattson , Jing Xu , Ajay Gopinathan

Intracellular bidirectional transport of cargo on microtubule filaments is achieved by the collective action of oppositely directed dynein and kinesin motors. Experiments have found that in certain cases, inhibiting the activity of one type…

Automated vehicles and logistics robots must often position themselves in narrow environments with high precision in front of a specific target, such as a package or their charging station. Often, these docking scenarios are solved in two…

Robotics · Computer Science 2025-04-07 Oliver Schumann , Michael Buchholz , Klaus Dietmayer

The dynamic behavior of microtubules in solution can be strongly modified by interactions with walls or other structures. We examine here a microtubule growth model where the increase in size of the plus-end is perturbed by collisions with…

Soft Condensed Matter · Physics 2010-09-29 Vladimir A. Baulin , Carlos M. Marques , Fabrice Thalmann

Tracer diffusion in crowded environments is central to many biological and soft matter systems, but quantitative frameworks for linking tracer motion to environmental structure remain limited. Here, we study the transport of rigid tracers…

Soft Condensed Matter · Physics 2026-05-07 Jinseok Lee , Tong Lin , Mengyang Gu , Yimin Luo

Neuronal growth cones are the most sensitive amongst eukaryotic cells in responding to directional chemical cues. Although a dynamic microtubule cytoskeleton has been shown to be essential for growth cone turning, the precise nature of…

Subcellular Processes · Quantitative Biology 2019-05-16 Saurabh Mahajan , Chaitanya A. Athale

In this paper a lattice model for diffusional transport of particles in the interphase cell nucleus is proposed. Dense networks of chromatin fibers are created by three different methods: randomly distributed, non-interconnected obstacles,…

Biological Physics · Physics 2009-11-13 Annika Wedemeier , Holger Merlitz , Chen-Xu Wu , Jörg Langowski

We derive a model describing spatio-temporal organization of an array of microtubules interacting via molecular motors. Starting from a stochastic model of inelastic polar rods with a generic anisotropic interaction kernel we obtain a set…

Soft Condensed Matter · Physics 2007-05-23 Igor S. Aronson , Lev S. Tsimring

Cellular cargo can be bound to cytoskeletal filaments by one or multiple active or passive molecular motors. Recent experiments have shown that the presence of auxiliary, nondriving motors, results in an enhanced processivity of the cargo,…

Biomolecules · Quantitative Biology 2019-03-27 Filippo Posta , Maria R. D'Orsogna , Tom Chou

Molecular motion through pores plays a crucial role in various natural and industrial processes. One of the most fascinating features of biological channel-facilitated transport is a stochastic gating process, when the channels dynamically…

Chemical Physics · Physics 2018-12-20 Aram Davtyan , Anatoly B. Kolomeisky

Biomolecular motor proteins that generate forces by consuming chemical energy obtained from ATP hydrolysis are pivotal for organizing broad cytoskeletal structures in living cells. The control of such cytoskeletal structures benefits…

Soft Condensed Matter · Physics 2021-12-30 Shunya Araki , Kazusa Beppu , Arif Md. Rashedul Kabir , Akira Kakugo , Yusuke T. Maeda

The cellular cytoskeleton is an active material, driven out of equilibrium by molecular motor proteins. It is not understood how the collective behaviors of cytoskeletal networks emerge from the properties of the network's constituent motor…

Subcellular Processes · Quantitative Biology 2017-12-19 Peter J. Foster , Wen Yan , Sebastian Fürthauer , Michael J. Shelley , Daniel J. Needleman

The plant microtubule cortical array is a striking feature of all growing plant cells. It consists of a more or less homogeneously distributed array of highly aligned microtubules connected to the inner side of the plasma membrane and…

Soft Condensed Matter · Physics 2013-05-29 Rhoda J. Hawkins , Simon H. Tindemans , Bela M. Mulder

In growing plant cells, parallel ordering of microtubules (MTs) along the inner surface of the cell membrane influences the direction of cell expansion and thereby plant morphology. For correct expansion of organs that primarily grow by…

Biological Physics · Physics 2019-09-05 Sven Bachmann , Richard Froese , Eric N Cytrynbaum