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In learning with noisy labels, the sample selection approach is very popular, which regards small-loss data as correctly labeled during training. However, losses are generated on-the-fly based on the model being trained with noisy labels,…

Machine Learning · Computer Science 2021-06-02 Xiaobo Xia , Tongliang Liu , Bo Han , Mingming Gong , Jun Yu , Gang Niu , Masashi Sugiyama

Deep learning-based histopathology image classification is a key technique to help physicians in improving the accuracy and promptness of cancer diagnosis. However, the noisy labels are often inevitable in the complex manual annotation…

Image and Video Processing · Electrical Eng. & Systems 2021-12-08 Chuang Zhu , Wenkai Chen , Ting Peng , Ying Wang , Mulan Jin

Instance segmentation has witnessed promising advancements through deep neural network-based algorithms. However, these models often exhibit incorrect predictions with unwarranted confidence levels. Consequently, evaluating prediction…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Qasim M. K. Siddiqui , Sebastian Starke , Peter Steinbach

Ensemble methods are generally regarded to be better than a single model if the base learners are deemed to be "accurate" and "diverse." Here we investigate a semi-supervised ensemble learning strategy to produce generalizable blind image…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Zhihua Wang , Dingquan Li , Kede Ma

Deep learning models are extensively used in various safety critical applications. Hence these models along with being accurate need to be highly reliable. One way of achieving this is by quantifying uncertainty. Bayesian methods for UQ…

Computer Vision and Pattern Recognition · Computer Science 2020-07-06 Swaroop Bhandary K , Nico Hochgeschwender , Paul Plöger , Frank Kirchner , Matias Valdenegro-Toro

Uncertainty estimation has been widely studied in medical image segmentation as a tool to provide reliability, particularly in deep learning approaches. However, previous methods generally lack effective supervision in uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Yuzhu Li , An Sui , Fuping Wu , Xiahai Zhuang

Learning against label noise is a vital topic to guarantee a reliable performance for deep neural networks. Recent research usually refers to dynamic noise modeling with model output probabilities and loss values, and then separates clean…

Machine Learning · Statistics 2022-07-13 Yingsong Huang , Bing Bai , Shengwei Zhao , Kun Bai , Fei Wang

Medical image segmentation supports clinical workflows by precisely delineating anatomical structures and lesions. However, medical image datasets medical image datasets suffer from acquisition noise and annotation ambiguity, causing…

Artificial Intelligence · Computer Science 2026-04-14 Ruiyang Li , Fang Liu , Licheng Jiao , Xinglin Xie , Jiayao Hao , Shuo Li , Xu Liu , Jingyi Yang , Lingling Li , Puhua Chen , Wenping Ma

Rigorous statistical methods, including parameter estimation with accompanying uncertainties, underpin the validity of scientific discovery, especially in the natural sciences. With increasingly complex data models such as deep learning…

Machine Learning · Computer Science 2026-02-18 Aurora Grefsrud , Nello Blaser , Trygve Buanes

Improper or erroneous labelling can pose a hindrance to reliable generalization for supervised learning. This can have negative consequences, especially for critical fields such as healthcare. We propose an effective new approach for…

Machine Learning · Computer Science 2021-11-16 Konstantinos Nikolaidis , Thomas Plagemann , Stein Kristiansen , Vera Goebel , Mohan Kankanhalli

Multiple Instance Learning is the predominant method for Whole Slide Image classification in digital pathology, enabling the use of slide-level labels to supervise model training. Although MIL eliminates the tedious fine-grained annotation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Chen Shu , Boyu Fu , Yiman Li , Ting Yin , Wenchuan Zhang , Jie Chen , Yuhao Yi , Hong Bu

Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in real-world applications: 1) only limited labels are available for model training, due to…

Computer Vision and Pattern Recognition · Computer Science 2020-08-26 Yifan Zhang , Ying Wei , Qingyao Wu , Peilin Zhao , Shuaicheng Niu , Junzhou Huang , Mingkui Tan

Deep learning is increasingly being applied in safety-critical domains. For these scenarios it is important to know the level of uncertainty in a model's prediction to ensure appropriate decisions are made by the system. Deep ensembles are…

Machine Learning · Computer Science 2022-03-17 Yassir Fathullah , Mark J. F. Gales

In semi-supervised medical image segmentation, the poor quality of unlabeled data and the uncertainty in the model's predictions lead to models that inevitably produce erroneous pseudo-labels. These errors accumulate throughout model…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Shiwei Zhou , Xin Liu , Haifeng Zhao , Bin Luo , Dengdi Sun

Uncertainty quantification is a critical aspect of reinforcement learning and deep learning, with numerous applications ranging from efficient exploration and stable offline reinforcement learning to outlier detection in medical…

Machine Learning · Computer Science 2025-03-27 Moritz A. Zanger , Pascal R. Van der Vaart , Wendelin Böhmer , Matthijs T. J. Spaan

Accurate segmentation of white matter hyperintensities (WMH) is crucial for clinical decision-making, particularly in the context of multiple sclerosis. However, domain shifts, such as variations in MRI machine types or acquisition…

Image and Video Processing · Electrical Eng. & Systems 2025-06-18 Franco Matzkin , Agostina Larrazabal , Diego H Milone , Jose Dolz , Enzo Ferrante

Deep learning (DL) has shown great potential in digital pathology applications. The robustness of a diagnostic DL-based solution is essential for safe clinical deployment. In this work we evaluate if adding uncertainty estimates for DL…

Machine Learning · Computer Science 2022-05-23 Milda Pocevičiūtė , Gabriel Eilertsen , Sofia Jarkman , Claes Lundström

Given data with label noise (i.e., incorrect data), deep neural networks would gradually memorize the label noise and impair model performance. To relieve this issue, curriculum learning is proposed to improve model performance and…

Machine Learning · Computer Science 2022-08-23 Tingting Wu , Xiao Ding , Hao Zhang , Jinglong Gao , Li Du , Bing Qin , Ting Liu

The drastic increase of data quantity often brings the severe decrease of data quality, such as incorrect label annotations, which poses a great challenge for robustly training Deep Neural Networks (DNNs). Existing learning \mbox{methods}…

Machine Learning · Computer Science 2022-03-18 Qizhou Wang , Bo Han , Tongliang Liu , Gang Niu , Jian Yang , Chen Gong

Brain vessel segmentation of MR scans is a critical step in the diagnosis of cerebrovascular diseases. Due to the fine vessel structure, manual vessel segmentation is time consuming. Therefore, automatic deep learning (DL) based…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Omini Rathore , Richard Paul , Abigail Morrison , Hanno Scharr , Elisabeth Pfaehler