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Many lung diseases require detailed visualisation for accurate diagnosis and treatment. High-resolution computed tomography (CT) is the gold-standard technique for non-invasive lung disease detection, but it presents a risk to the patient…

Dark-field contrast imaging with grating interferometers has proven to hold huge potential for numerous applications with X-rays and with neutrons conveying biology and medicine as well as engineering and magnetism, respectively. However, a…

Materials Science · Physics 2013-12-03 Markus Strobl

Computational anatomy allows the quantitative analysis of organs in medical images. However, most analysis is constrained to the millimeter scale because of the limited resolution of clinical computed tomography (CT). X-ray microtomography…

Computer Vision and Pattern Recognition · Computer Science 2017-02-28 Holger R. Roth , Kai Nagara , Hirohisa Oda , Masahiro Oda , Tomoshi Sugiyama , Shota Nakamura , Kensaku Mori

Breast CT provides image volumes with isotropic resolution in high contrast, enabling detection of small calcification (down to a few hundred microns in size) and subtle density differences. Since breast is sensitive to x-ray radiation,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Huidong Xie , Hongming Shan , Wenxiang Cong , Chi Liu , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Ge Wang

Magnetic resonance imaging (MRI) is an invaluable tool for clinical and research applications. Yet, variations in scanners and acquisition parameters cause inconsistencies in image contrast, hindering data comparability and reproducibility…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Robbie Holland , Viktoria Ehm , Jan C. Peeken , Benedikt Wiestler , Daniel Rueckert

Knowledge of x-ray attenuation is essential for developing and evaluating x-ray imaging technologies. For instance, techniques to distinguish between cysts and solid tumours at mammography screening would be highly desirable to reduce…

While drastic improvements in CT technology have occurred in the past 25 years, spatial resolution is one area where progress has been limited until recently. New photon counting CT systems, are capable of much better spatial resolution…

This paper presents a method for virtual contrast enhancement in breast MRI, offering a promising non-invasive alternative to traditional contrast agent-based DCE-MRI acquisition. Using a conditional generative adversarial network, we…

Image and Video Processing · Electrical Eng. & Systems 2025-05-15 Richard Osuala , Smriti Joshi , Apostolia Tsirikoglou , Lidia Garrucho , Walter H. L. Pinaya , Daniel M. Lang , Julia A. Schnabel , Oliver Diaz , Karim Lekadir

X-ray grating interferometry is an excellent technique for X-ray phase contrast imaging and X-ray wavefront sensing with applications in materials science, biology and medical diagnosis. Among other requirements, the method depends on the…

Background: Perfusion computed tomography (CT) images the dynamics of a contrast agent through the body over time, and is one of the highest X-ray dose scans in medical imaging. Recently, a theoretically justified reconstruction algorithm…

Medical Physics · Physics 2026-02-04 Namhoon Kim , Ashwin Pananjady , Amir Pourmorteza , Sara Fridovich-Keil

Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Wenjun Xia , Yongyi Shi , Chuang Niu , Wenxiang Cong , Ge Wang

Computed Tomography (CT) scans are the standard-of-care for the visualization and diagnosis of many clinical ailments, and are needed for the treatment planning of external beam radiotherapy. Unfortunately, the availability of CT scanners…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Yiran Sun , Hana Baroudi , Tucker Netherton , Laurence Court , Osama Mawlawi , Ashok Veeraraghavan , Guha Balakrishnan

Chest computed tomography (CT) imaging adds valuable insight in the diagnosis and management of pulmonary infectious diseases, like tuberculosis (TB). However, due to the cost and resource limitations, only X-ray images may be available for…

Image and Video Processing · Electrical Eng. & Systems 2022-11-16 Elena Sizikova , Xu Cao , Ashia Lewis , Kenny Moise , Megan Coffee

Breast cancer is the most prevalent cancer among women worldwide, and early detection is crucial for reducing its mortality rate and improving quality of life. Dedicated breast computed tomography (CT) scanners offer better image quality…

Image and Video Processing · Electrical Eng. & Systems 2024-01-30 Wenjun Xia , Hsin Wu Tseng , Chuang Niu , Wenxiang Cong , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Srinivasan Vedantham , Ge Wang

X-ray imaging is a prevalent technique for non-invasively visualizing the interior of the human body and opaque instruments. In most commercial x-ray modalities, an image is formed by measuring the x-rays that pass through the object of…

Medical Physics · Physics 2023-05-23 A. Ben Yehuda , O. Sefi , Y. Klein , R. H Shukrun , H. Schwartz , E. Cohen , S. Shwartz

Dynamic Contrast Enhanced-Magnetic Resonance Imaging (DCE-MRI) is widely used to complement ultrasound examinations and x-ray mammography during the early detection and diagnosis of breast cancer. However, images generated by various MRI…

Image and Video Processing · Electrical Eng. & Systems 2021-06-18 Gourav Modanwal , Adithya Vellal , Maciej A. Mazurowski

X-ray interferometry is an emerging imaging modality with a wide variety of potential clinical applications, including lung and breast imaging, as well as in non-destructive testing, such as additive manufacturing and porosimetry. A grating…

The development of new x-ray imaging techniques often requires prior knowledge of tissue attenuation, but the sources of such information are sparse. We have measured the attenuation of adipose breast tissue using spectral imaging, in vitro…

X-ray diffraction tomography (XDT) resolves spatially-variant XRD profiles within macroscopic objects, and provides improved material contrast compared to the conventional transmission-based computed tomography (CT). However, due to the…

Medical Physics · Physics 2019-01-04 Zheyuan Zhu , Alexander Katsevich , Shuo Pang

Fabrication of X-ray gratings has surged in the last two decades thanks to their vast employment in X-ray Phase Contrast Imaging, an imaging technique able to boost X-ray sensitivity to detect otherwise invisible details. These high aspect…