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Related papers: Enzyme-enriched condensates show self-propulsion, …

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Conventional gas-liquid phase transitions feature a coexistence line that has a monotonic and positive slope in line with our intuition that cooling always leads to condensation. Here we study the inverse phenomenon, condensation of…

Statistical Mechanics · Physics 2023-07-21 Joël A. K. L. Picard , T. Speck

Mechanochemically active enzymes change their shapes within every turnover cycle. Therefore, they induce circulating flows in the solvent around them and behave as oscillating hydrodynamic force dipoles. Because of non-equilibrium…

Soft Condensed Matter · Physics 2021-12-28 Yuto Hosaka , Shigeyuki Komura , Alexander S. Mikhailov

Exciton-polariton condensation occurs at the extrema of the underlying dispersion where the density of states diverges and carriers can naturally accumulate. The existence of multiple such points leads to coupling and competition between…

Key enzymatic processes in biology use the nonequilibrium error correction mechanism called kinetic proofreading to enhance their specificity. Kinetic proofreading typically requires several dedicated structural features in the enzyme, such…

Molecular Networks · Quantitative Biology 2020-05-26 Vahe Galstyan , Kabir Husain , Fangzhou Xiao , Arvind Murugan , Rob Phillips

Ensembles of particles rotating in a two-dimensional fluid can exhibit chaotic dynamics yet develop signatures of hidden order. Such "rotors" are found in the natural world spanning vastly disparate length scales - from the rotor proteins…

Soft Condensed Matter · Physics 2022-03-09 Naomi Oppenheimer , David B. Stein , Matan Yah Ben Zion , Michael J. Shelley

Self-organization phenomena in ensembles of self-propelled particles open pathways to the synthesis of new dynamic states not accessible by traditional equilibrium processes. The challenge is to develop a set of principles that facilitate…

Soft Condensed Matter · Physics 2022-05-26 Bo Zhang , Alexey Snezhko , Andrey Sokolov

Many active fluid systems encountered in biology are set in total geometric confinement. Cytoplasmic streaming in plant cells is a prominent and ubiquitous example, in which cargo-carrying molecular motors move along polymer filaments and…

Soft Condensed Matter · Physics 2013-01-10 Francis G. Woodhouse , Raymond E. Goldstein

A particle driven by an external force in a molecular crowding environment - a quiescent bath of other particles, makes their spatial distribution inhomogeneous: the bath particles accumulate in front of the biased particle (BP) and are…

Soft Condensed Matter · Physics 2011-09-08 Carlos Mejia-Monasterio , Gleb Oshanin

Diffusive transport of particles or, more generally, small objects is a ubiquitous feature of physical and chemical reaction systems. In configurations containing confining walls or constrictions transport is controlled both by the…

Statistical Mechanics · Physics 2009-01-22 P. Sekhar Burada , Peter Hanggi , Fabio Marchesoni , Gerhard Schmid , Peter Talkner

The interior of a living cell is an active, fluctuating, and crowded environment. Yet, it maintains a high level of coherent organization, which is readily apparent in the intracellular transport network. Membrane-bound compartments called…

We consider stochastic rules of mass transport which lead to steady states that factorize over the links of a one-dimensional ring. Based on the knowledge of the steady states, we derive the onset of a phase transition from a liquid to a…

Statistical Mechanics · Physics 2015-05-13 B. Waclaw , J. Sopik , W. Janke , H. Meyer-Ortmanns

Random non-reciprocal interactions between a large number of conserved densities are shown to enhance the stability of the system towards pattern formation. The enhanced stability is an exact result when the number of species approaches…

Soft Condensed Matter · Physics 2025-10-08 Laya Parkavousi , Navdeep Rana , Ramin Golestanian , Suropriya Saha

Cells generally convert nutrient resources to useful products via energy transduction. Accordingly, the thermodynamic efficiency of this conversion process is one of the most essential characteristics of living organisms. However, although…

Biological Physics · Physics 2016-05-04 Yusuke Himeoka , Kunihiko Kaneko

We investigate the transport dynamics of elongated particles in cellular vortical flows that undergo spatial oscillations over time. Experimental flow visualizations reveal mixed flow fields with chaotic and elliptic regions coexisting.…

Fluid Dynamics · Physics 2025-08-14 Shiyuan Hu , Xiuyuan Yang , Nan Luo , Jun Zhang , Xingkun Man

We study analytically and numerically a model metabolic cycle composed of an arbitrary number of species of catalytically active particles. Each species converts a substrate into a product, the latter being used as the substrate by the next…

Soft Condensed Matter · Physics 2023-09-29 Vincent Ouazan-Reboul , Jaime Agudo-Canalejo , Ramin Golestanian

A growing amount of evidence points to the fact that many enzymes exhibit fluctuations in their catalytic activity, which are associated with conformational changes on a broad range of timescales. The experimental study of this phenomenon,…

Quantitative Methods · Quantitative Biology 2017-07-28 Ankit Gupta , Andreas Milias-Argeitis , Mustafa Khammash

The investigation of collective behaviour in dense assemblies of self-propelled active particles has been motivated by a wide range of biological phenomena. Of particular interest are dynamical transitions of cellular and sub-cellular…

Soft Condensed Matter · Physics 2023-12-05 Yagyik Goswami , G. V. Shivashankar , Srikanth Sastry

We present a detailed numerical study of the dynamics of a disordered one-dimensional Bose-Einstein condensates in position and momentum space. We particularly focus on the region where non-linearity and disorder simultaneously effect the…

Mesoscale and Nanoscale Physics · Physics 2011-01-18 Chaitanya Joshi , Sankalpa Ghosh

We examine colloidal particles driven over a periodic muffin tin substrate using numerical simulations. In the absence of a driving force this system exhibits a rich variety of commensurate and incommensurate static phases in which…

Soft Condensed Matter · Physics 2015-06-16 D. McDermott , J. Amelang , C. J. Olson Reichhardt , C. Reichhardt

Entropy-driven equilibrium phase behaviour of hard particle dispersions can be understood from excluded volume arguments only. While monodisperse hard spheres only exhibit a fluid-solid phase transition, anisotropic hard particles such as…

Soft Condensed Matter · Physics 2017-12-07 Á. González García , H. H. Wensink , H. N. W. Lekkerkerker , R. Tuinier