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In functional MRI (fMRI), effective connectivity analysis aims at inferring the causal influences that brain regions exert on one another. A common method for this type of analysis is structural equation modeling (SEM). We here propose a…

Quantitative Methods · Quantitative Biology 2024-09-10 G. Marrelec , A. Giron

Objective: Electroencephalography (EEG) and electromyography (EMG) are two non-invasive bio-signals, which are widely used in human machine interface (HMI) technologies (EEG-HMI and EMG-HMI paradigm) for the rehabilitation of physically…

Neurons and Cognition · Quantitative Biology 2022-06-23 Omair Ali , Muhammad Saif-ur-Rehman , Tobias Glasmachers , Ioannis Iossifidis , Christian Klaes

Electroencephalography (EEG) has wide-ranging applications, from clinical diagnosis to brain-computer interfaces (BCIs). With the increasing volume and variety of EEG data, there has been growing interest in establishing foundation models…

Machine Learning · Computer Science 2025-10-21 Zitao Fang , Chenxuan Li , Hongting Zhou , Shuyang Yu , Guodong Du , Ashwaq Qasem , Yang Lu , Jing Li , Junsong Zhang , Sim Kuan Goh

Neuronal dynamics are fundamentally constrained by the underlying structural network architecture, yet much of the details of this synaptic connectivity are still unknown even in neuronal cultures in vitro. Here we extend a previous…

Neurons and Cognition · Quantitative Biology 2017-02-08 Javier G. Orlandi , Olav Stetter , Jordi Soriano , Theo Geisel , Demian Battaglia

In previous studies, decoding electroencephalography (EEG) signals has not considered the topological relationship of EEG electrodes. However, the latest neuroscience has suggested brain network connectivity. Thus, the exhibited interaction…

Signal Processing · Electrical Eng. & Systems 2020-07-28 Shuyue Jia , Yimin Hou , Yan Shi , Yang Li

Recent studies have shown that multi-modeling methods can provide new insights into the analysis of brain components that are not possible when each modality is acquired separately. The joint representations of different modalities is a…

Neurons and Cognition · Quantitative Biology 2022-01-24 Jalal Mirakhorli

In modern clinical trials, there is immense pressure to use surrogate markers in place of an expensive or long-term primary outcome to make more timely decisions about treatment effectiveness. However, using a surrogate marker to test for a…

Methodology · Statistics 2025-04-22 Rebecca Knowlton , Layla Parast

A series of papers has developed a statistical mechanics of neocortical interactions (SMNI), deriving aggregate behavior of experimentally observed columns of neurons from statistical electrical-chemical properties of synaptic interactions.…

Biological Physics · Physics 2009-11-06 Lester Ingber

Recently, there have been several concerted international efforts - the BRAIN initiative, European Human Brain Project and the Human Connectome Project, to name a few - that hope to revolutionize our understanding of the connected brain.…

Neurons and Cognition · Quantitative Biology 2016-02-10 Adeel Razi , Karl Friston

Although nonstationary data are more common in the real world, most existing causal discovery methods do not take nonstationarity into consideration. In this letter, we propose a kernel embedding-based approach, ENCI, for nonstationary…

Machine Learning · Statistics 2018-09-25 Shoubo Hu , Zhitang Chen , Laiwan Chan

Prior work on probing neural networks primarily relies on input-space analysis or parameter perturbation, both of which face fundamental limitations in accessing structural information encoded in intermediate representations. We introduce…

Machine Learning · Computer Science 2026-02-04 Tao Ren , Xiaoyu Luo , Qiongxiu Li

Learning the spatial topology of electroencephalogram (EEG) channels and their temporal dynamics is crucial for decoding attention states. This paper introduces EEG-PatchFormer, a transformer-based deep learning framework designed…

Signal Processing · Electrical Eng. & Systems 2025-05-20 Yi Ding , Joon Hei Lee , Shuailei Zhang , Tianze Luo , Cuntai Guan

Effective connectivity analysis provides an understanding of the functional organization of the brain by studying how activated regions influence one other. We propose a nonparametric Bayesian approach to model effective connectivity…

Applications · Statistics 2011-07-22 Sourabh Bhattacharya , Ranjan Maitra

The brain's diversity of neurons enables a rich behavioral repertoire and flexible adaptation to new situations. Assuming that the ecological pressure has optimized this neuronal variety, we propose exploiting na\"ive behavior to map the…

Neurons and Cognition · Quantitative Biology 2023-05-01 Kevin Luxem , David Eriksson

Cognitive maps provide a powerful framework for understanding spatial and abstract reasoning in biological and artificial agents. While recent computational models link cognitive maps to hippocampal-entorhinal mechanisms, they often rely on…

Neurons and Cognition · Quantitative Biology 2025-10-07 E. A. Dzhivelikian , A. I. Panov

This tutorial provides a worked example of using Dynamic Causal Modelling (DCM) and Parametric Empirical Bayes (PEB) to characterise inter-subject variability in neural circuitry (effective connectivity). This involves specifying a…

Quantitative Methods · Quantitative Biology 2019-07-15 Peter Zeidman , Amirhossein Jafarian , Mohamed L. Seghier , Vladimir Litvak , Hayriye Cagnan , Cathy J. Price , Karl J. Friston

Neural network oscillations are a fundamental mechanism for cognition, perception and consciousness. Consequently, perturbations of network activity play an important role in the pathophysiology of brain disorders. When structural…

Neurons and Cognition · Quantitative Biology 2016-04-29 Timothée Proix , Fabrice Bartolomei , Maxime Guye , Viktor K. Jirsa

In the domain of causal inference research, the prevalent potential outcomes framework, notably the Rubin Causal Model (RCM), often overlooks individual interference and assumes independent treatment effects. This assumption, however, is…

Methodology · Statistics 2024-02-21 Hongtao Zhu , Sizhe Zhang , Yang Su , Zhenyu Zhao , Nan Chen

A brain-computer interface (BCI) based on electroencephalography (EEG) can be useful for rehabilitation and the control of external devices. Five grasping tasks were decoded for motor execution (ME) and motor imagery (MI). During this…

Human-Computer Interaction · Computer Science 2022-12-15 Jeong-Hyun Cho , Byoung-Hee Kwon , Byeong-Hoo Lee

Despite substantial research into the biological basis of memory, the precise mechanisms by which experiences are encoded, stored, and retrieved in the brain remain incompletely understood. A growing body of evidence supports the engram…

Neural and Evolutionary Computing · Computer Science 2025-10-28 Daniel Szelogowski