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A class of reaction-diffusion virus dynamics models with intracellular state-dependent delay and a general non-linear infection rate functional response is investigated. We are interested in classical solutions with Lipschitz in-time…

Dynamical Systems · Mathematics 2019-01-01 Alexander Rezounenko

A virus dynamics model with intracellular state-dependent delay and nonlinear infection rate of Beddington-DeAngelis functional response is studied. The technique of Lyapunov functionals is used to analyze stability of an interior infection…

Dynamical Systems · Mathematics 2017-06-29 Alexander Rezounenko

In this paper, we investigate global dynamics for a system of delay differential equations which describes a virus-immune interaction in \textit{vivo}. The model has two distributed time delays describing time needed for infection of cell…

Dynamical Systems · Mathematics 2010-08-17 Yukihiko Nakata

We consider mathematical models of infection diseases built by G.I. Marchuk in his well known book on immunology. These models are in the form of systems of ordinary delay differential equations. We add a distributed control in one of the…

Cell Behavior · Quantitative Biology 2020-08-28 Irina Volinsky , Alexander Domoshnitsky , Marina Bershadsky , Roman Shklyar

A retrovirus dynamic model is proposed. We pay attention to the case when viral pathogenicity is low and the infected cells are able to reproduce. Using Lyapunov function method we study stability properties of an inner equilibrium of the…

Dynamical Systems · Mathematics 2019-01-01 Andrei Korobeinikov , Alexander Rezounenko

In this paper, we discussed an infinitely distributed delayed viral infection model with nonlinear immune response and general incidence rate. We proved the existence and uniqueness of the equilibria. By using the Lyapunov functional and…

Dynamical Systems · Mathematics 2018-02-13 Eric Ávila-Vales , Abraham Canul-Pech , Erika Rivero Esquivel

An epidemic model with distributed time delay is derived to describe the dynamics of infectious diseases with varying immunity. It is shown that solutions are always positive, and the model has at most two steady states: disease-free and…

Chaotic Dynamics · Physics 2012-09-21 K. B. Blyuss , Y. N. Kyrychko

In this contribution, the estimates for the response of time delay systems with nonlinear homogeneous right-hand side of degree strictly greater than one are constructed. The existing results obtained via the Lyapunov--Razumikhin approach…

Systems and Control · Electrical Eng. & Systems 2021-05-11 Gerson Portilla , Irina Alexandrova , Sabine Mondié , Alexey Zhabko

In the paper we consider a system of differential equations with two delays describing plankton--fish interaction. We study stability of the equilibrium point corresponding to the presence of phytoplankton and zooplankton in the system and…

Dynamical Systems · Mathematics 2023-12-20 M. A. Skvortsova

We study the global stability of a class of models for in-vivo virus dynamics, that take into account the CTL immune response and display antigenic variation. This class includes a number of models that have been extensively used to model…

Populations and Evolution · Quantitative Biology 2013-01-21 Max O. Souza , Jorge P. Zubelli

In this chapter, we consider a reaction-diffusion SVIR infection model with dis-tributed delay and nonlinear incidence rate. The wellposedness of the proposed model is proved. By means of Lyapunov functionals, we show that the disease-free…

Dynamical Systems · Mathematics 2025-03-10 Achraf Zinihi , Mostafa Tahiri , Moulay Rchid Sidi Ammi

In this paper, we present estimates for solutions and for the attraction domain of the trivial solution for systems with delayed and nonlinear weighted homogeneous right-hand side of positive degree. The results are achieved via a…

Systems and Control · Electrical Eng. & Systems 2021-01-27 Gerson Portilla , Irina Alexandrova , Sabine Mondié

This paper is concerned with stability analysis of nonlinear time-varying systems by using Lyapunov function based approach. The classical Lyapunov stability theorems are generalized in the sense that the time-derivative of the Lyapunov…

Dynamical Systems · Mathematics 2017-08-18 Bin Zhou

This book is an extension of my doctoral dissertation, focusing on techniques for analyzing stability (dissipativity) and achieving stabilization of linear systems that are characterized by non-trivial distributed delays. It specifically…

Optimization and Control · Mathematics 2024-04-09 Qian Feng , Alexandre Seuret , Sing Kiong Nguang

In [Math. Comput. Sci. 12 (2018), no. 2, 111--127], a delayed model describing the dynamics of the Human Immunodeficiency Virus (HIV) with Cytotoxic T Lymphocytes (CTL) immune response is investigated by Allali, Harroudi and Torres. Here,…

Dynamical Systems · Mathematics 2022-10-03 Sandra Vaz , Delfim F. M. Torres

In this article, we provide a general strategy based on Lyapunov functionals to analyse global asymptotic stability of linear infinite-dimensional systems subject to nonlinear dampings under the assumption that the origin of the system is…

Analysis of PDEs · Mathematics 2018-08-17 Swann Marx , Yacine Chitour , Christophe Prieur

We examine the properties of a recently proposed model for antigenic variation in malaria which incorporates multiple epitopes and both long-lasting and transient immune responses. We show that in the case of a vanishing decay rate for the…

Chaotic Dynamics · Physics 2012-09-21 K. B. Blyuss , S. Gupta

The paper deals with the global asymptotic stability of general nonlinear time-delay systems with delay-dependent impulses through the Lyapunov-Krasovskii method. We derive a unified stability criterion which can be applied to a variety of…

Dynamical Systems · Mathematics 2022-06-09 Kexue Zhang , Elena Braverman

In this paper, we propose a delayed cytokine-enhanced viral infection model incorporating saturation incidence and immune response. We compute the basic reproduction numbers and introduce a convex cone to discuss the impact of non-negative…

Dynamical Systems · Mathematics 2024-09-17 Xiaodong Cao , Songbo Hou , Xiaoqing Kong

A Lyapunov-Krasovskii functional with prescribed derivative whose construction does not require the stability of the system is introduced. It leads to the presentation of stability/instability theorems. By evaluating the functional at…

Systems and Control · Electrical Eng. & Systems 2023-09-12 Reynaldo Ortiz , Alexey Egorov , Sabine Mondié
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