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As artificial intelligence plays an increasingly important role in our society, there are ethical and moral obligations for both businesses and researchers to ensure that their machine learning models are designed, deployed, and maintained…

Machine Learning · Computer Science 2020-07-07 Shubham Sharma , Jette Henderson , Joydeep Ghosh

The widespread use of Artificial Intelligence-based tools in the healthcare sector raises many ethical and legal problems, one of the main reasons being their black-box nature and therefore the seemingly opacity and inscrutability of their…

The use of Artificial Intelligence (AI) models in real-world and high-risk applications has intensified the discussion about their trustworthiness and ethical usage, from both a technical and a legislative perspective. The field of…

Machine Learning · Computer Science 2025-12-17 Ilaria Vascotto , Alex Rodriguez , Alessandro Bonaita , Luca Bortolussi

Modern AI systems frequently rely on opaque black-box models, most notably Deep Neural Networks, whose performance stems from complex architectures with millions of learned parameters. While powerful, their complexity poses a major…

Machine Learning · Computer Science 2026-02-23 David Dembinsky , Adriano Lucieri , Stanislav Frolov , Hiba Najjar , Ko Watanabe , Andreas Dengel

Artificial Intelligence (AI) systems are now an integral part of multiple industries. In clinical research, AI supports automated adverse event detection in clinical trials, patient eligibility screening for protocol enrollment, and data…

Artificial Intelligence · Computer Science 2025-12-10 Laxmiraju Kandikatla , Branislav Radeljic

The integration of Artificial Intelligence in the development of computer systems presents a new challenge: make intelligent systems explainable to humans. This is especially vital in the field of health and well-being, where transparency…

Artificial Intelligence (AI) is rapidly embedded in critical decision-making systems, however their foundational ``black-box'' models require eXplainable AI (XAI) solutions to enhance transparency, which are mostly oriented to experts,…

Machine Learning · Computer Science 2025-06-17 Eva Paraschou , Ioannis Arapakis , Sofia Yfantidou , Sebastian Macaluso , Athena Vakali

The integration of Artificial Intelligence (AI) into high-stakes domains such as healthcare, finance, and autonomous systems is often constrained by concerns over transparency, interpretability, and trust. While Human-Centered AI (HCAI)…

Human-Computer Interaction · Computer Science 2025-04-29 Chameera De Silva , Thilina Halloluwa , Dhaval Vyas

Artificial intelligence is reshaping science and industry, yet many users still regard its models as opaque "black boxes". Conventional explainable artificial-intelligence methods clarify individual predictions but overlook the upstream…

Machine Learning · Computer Science 2025-08-18 George Paterakis , Andrea Castellani , George Papoutsoglou , Tobias Rodemann , Ioannis Tsamardinos

Many ML models are opaque to humans, producing decisions too complex for humans to easily understand. In response, explainable artificial intelligence (XAI) tools that analyze the inner workings of a model have been created. Despite these…

Computers and Society · Computer Science 2021-06-17 Kiana Alikhademi , Brianna Richardson , Emma Drobina , Juan E. Gilbert

In a world of daily emerging scientific inquisition and discovery, the prolific launch of machine learning across industries comes to little surprise for those familiar with the potential of ML. Neither so should the congruent expansion of…

Artificial Intelligence · Computer Science 2021-12-13 Brianna Richardson , Juan E. Gilbert

In today's data-driven era, computational systems generate vast amounts of data that drive the digital transformation of industries, where Artificial Intelligence (AI) plays a key role. Currently, the demand for eXplainable AI (XAI) has…

Artificial Intelligence · Computer Science 2025-03-07 Georgios Makridis , Vasileios Koukos , Georgios Fatouros , Dimosthenis Kyriazis

The trustworthiness of Machine Learning (ML) models can be difficult to assess, but is critical in high-risk or ethically sensitive applications. Many models are treated as a `black-box' where the reasoning or criteria for a final decision…

Machine Learning · Computer Science 2024-07-11 Saif Anwar , Nathan Griffiths , Abhir Bhalerao , Thomas Popham

The field of explainable AI (XAI) has quickly become a thriving and prolific community. However, a silent, recurrent and acknowledged issue in this area is the lack of consensus regarding its terminology. In particular, each new…

Artificial Intelligence · Computer Science 2021-11-03 Sebastian Palacio , Adriano Lucieri , Mohsin Munir , Jörn Hees , Sheraz Ahmed , Andreas Dengel

The rise of machine learning (ML) is accompanied by several high-profile cases that have stressed the need for fairness, accountability, explainability and trust in ML systems. The existing literature has largely focused on fully automated…

Computers and Society · Computer Science 2023-06-14 Bhavya Ghai

Fairness of machine learning models in healthcare has drawn increasing attention from clinicians, researchers, and even at the highest level of government. On the other hand, the importance of developing and deploying interpretable or…

Machine Learning · Computer Science 2024-09-04 Mary M. Lucas , Xiaoyang Wang , Chia-Hsuan Chang , Christopher C. Yang , Jacqueline E. Braughton , Quyen M. Ngo

Explainable Artificial Intelligence (XAI) is an emerging research field bringing transparency to highly complex and opaque machine learning (ML) models. Despite the development of a multitude of methods to explain the decisions of black-box…

Machine Learning · Computer Science 2022-03-16 Leander Weber , Sebastian Lapuschkin , Alexander Binder , Wojciech Samek

Deep learning models are being increasingly applied to imbalanced data in high stakes fields such as medicine, autonomous driving, and intelligence analysis. Imbalanced data compounds the black-box nature of deep networks because the…

Machine Learning · Computer Science 2022-12-16 Damien A. Dablain , Colin Bellinger , Bartosz Krawczyk , David W. Aha , Nitesh V. Chawla

In the ever-expanding landscape of Artificial Intelligence (AI), where innovation thrives and new products and services are continuously being delivered, ensuring that AI systems are designed and developed responsibly throughout their…

Software Engineering · Computer Science 2024-05-10 Maria Teresa Baldassarre , Domenico Gigante , Marcos Kalinowski , Azzurra Ragone

Recently, post hoc explanation methods have emerged to enhance model transparency by attributing model outputs to input features. However, these methods face challenges due to their specificity to certain neural network architectures and…

Machine Learning · Computer Science 2025-05-16 Seongun Kim , Sol A Kim , Geonhyeong Kim , Enver Menadjiev , Chanwoo Lee , Seongwook Chung , Nari Kim , Jaesik Choi
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