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Generative AI (GenAI) has fundamentally changed how knowledge workers, such as software developers, solve tasks and collaborate to build software products. Introducing innovative tools like ChatGPT and Copilot has created new opportunities…

Software Engineering · Computer Science 2024-05-06 Rasmus Ulfsnes , Nils Brede Moe , Viktoria Stray , Marianne Skarpen

One of the notable fields in studying the genetics of cancer is disease gene identification which affects disease treatment and drug discovery. Many researches have been done in this field. Genome-wide association studies (GWAS) are one of…

Computational Engineering, Finance, and Science · Computer Science 2016-04-27 Zahra Razaghi-Moghadama , Razieh Abdollahia , Sama Goliaeib , Morteza Ebrahimia

Most LLM-driven GIS assistants solve narrow single-step tasks tightly coupled to proprietary platforms such as ArcGIS or QGIS, limiting their use for the multi-step, cross-format pipelines that define professional geospatial analysis. We…

Software Engineering · Computer Science 2026-05-05 Jinzhen Han , JinByeong Lee , Yuri Shim , Jisung Kim , Jae-Joon Lee

Complex systems with tightly coadapted parts frequently appear in living systems and are difficult to account for through Darwinian evolution, that is random variation and natural selection, if the constituent parts are independently coded…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 John F. McGowan , Ph. D

GeneVis is a web-based tool to visualize complementary data sets of different disciplines within the field of genetics. It overlays gene-cluster information, gene-interaction data and gene-disease association data by means of web-based…

Graphics · Computer Science 2018-05-08 Casper van Leeuwen

Motivation: Genome-Wide Association Studies (GWAS) seek to identify causal genomic variants associated with rare human diseases. The classical statistical approach for detecting these variants is based on univariate hypothesis testing, with…

Methodology · Statistics 2018-10-22 Florent Guinot , Marie Szafranski , Christophe Ambroise , Franck Samson

Constraint-based applications attempt to identify a solution that meets all defined user requirements. If the requirements are inconsistent with the underlying constraint set, algorithms that compute diagnoses for inconsistent constraints…

Artificial Intelligence · Computer Science 2023-08-15 Viet-Man Le , Cristian Vidal Silva , Alexander Felfernig , David Benavides , José Galindo , Thi Ngoc Trang Tran

Access to genomic data is highly regulated due to its sensitive nature. While safeguards are essential, cumbersome data access processes pose a significant barrier to the development of AI methods for genomics. Synthetic data generation can…

Cryptography and Security · Computer Science 2026-05-01 Daniil Filienko , Martine De Cock , Sikha Pentyala

Novel technologies in genomics allow creating data in exascale dimension with relatively minor effort of human and laboratory and thus monetary resources compared to capabilities only a decade ago. While the availability of this data…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-11-10 Sandra Gesing , Thomas Richard Connor , Ian Taylor

Data generation is a key issue in big data benchmarking that aims to generate application-specific data sets to meet the 4V requirements of big data. Specifically, big data generators need to generate scalable data (Volume) of different…

Databases · Computer Science 2014-02-28 Zijian Ming , Chunjie Luo , Wanling Gao , Rui Han , Qiang Yang , Lei Wang , Jianfeng Zhan

Research collaborations are continuously emerging catalyzed by online platforms, where people can share their codes, calculations, data and results. These virtual research platforms are innovative, community oriented, flexible and secure as…

There are numerous approaches to building analysis applications across the high-energy physics community. Among them are Python-based, or at least Python-driven, analysis workflows. We aim to ease the adoption of a Python-based analysis…

Computational Physics · Physics 2018-04-25 David Lange

Today's sequencing technology allows sequencing an individual genome within a few weeks for a fraction of the costs of the original Human Genome project. Genomics labs are faced with dozens of TB of data per week that have to be…

Databases · Computer Science 2009-09-15 Uwe Roehm , Jose Blakeley

Objective: To (1) demonstrate the implementation of a data science platform built on open-source technology within a large, academic healthcare system and (2) describe two computational healthcare applications built on such a platform.…

Clustering is an essential technique for discovering patterns in data. The steady increase in amount and complexity of data over the years led to improvements and development of new clustering algorithms. However, algorithms that can…

Machine Learning · Statistics 2021-03-03 Shu Wang , Jonathan G. Yabes , Chung-Chou H. Chang

JINet is a web browser-based platform intended to democratise access to advanced clinical and genomic data analysis software. It hosts numerous data analysis applications that are run in the safety of each User's web browser, without the…

Computers and Society · Computer Science 2024-08-30 Giada Lalli , James Collier , Yves Moreau , Daniele Raimondi

Qualitative research delves deeply into individual complex perspectives on technology and various phenomena. However, a meticulous analysis of qualitative data often requires a significant amount of time, especially during the crucial…

Human-Computer Interaction · Computer Science 2023-10-12 He Zhang , Chuhao Wu , Jingyi Xie , ChanMin Kim , John M. Carroll

Cognitive diagnosis plays a vital role in modern intelligent education platforms to reveal students' proficiency in knowledge concepts for subsequent adaptive tasks. However, due to the requirement of high model interpretability, existing…

Neural and Evolutionary Computing · Computer Science 2023-07-11 Shangshang Yang , Haiping Ma , Cheng Zhen , Ye Tian , Limiao Zhang , Yaochu Jin , Xingyi Zhang

Repetitive DNA (repeats) poses significant challenges for accurate and efficient genome assembly and sequence alignment. This is particularly true for metagenomic data, where genome dynamics such as horizontal gene transfer, gene…

Machine Learning · Computer Science 2024-02-15 Ali Azizpour , Advait Balaji , Todd J. Treangen , Santiago Segarra

Multiplexed imaging data are revolutionizing our understanding of the composition and organization of tissues and tumors. A critical aspect of such tissue profiling is quantifying the spatial relationship relationships among cells at…

Quantitative Methods · Quantitative Biology 2024-05-06 Ajit J. Nirmal , Peter K. Sorger
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