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Deep convolutional neural networks have achieved remarkable progress on a variety of medical image computing tasks. A common problem when applying supervised deep learning methods to medical images is the lack of labeled data, which is very…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

We introduce Segmentation by Factorization (F-SEG), an unsupervised segmentation method for pathology that generates segmentation masks from pre-trained deep learning models. F-SEG allows the use of pre-trained deep neural networks,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Jacob Gildenblat , Ofir Hadar

Recent advancements in artificial intelligence (AI) have precipitated a paradigm shift in medical imaging, particularly revolutionizing the domain of brain imaging. This paper systematically investigates the integration of deep learning --…

Image and Video Processing · Electrical Eng. & Systems 2024-10-18 Houze Liu , Bo Zhang , Yanlin Xiang , Yuxiang Hu , Aoran Shen , Yang Lin

Cell nuclei segmentation is one of the most important tasks in the analysis of biomedical images. With ever-growing sizes and amounts of three-dimensional images to be processed, there is a need for better and faster segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Julian Arz , Peter Sanders , Johannes Stegmaier , Ralf Mikut

In recent years, deep convolutional neural network-based segmentation methods have achieved state-of-the-art performance for many medical analysis tasks. However, most of these approaches rely on optimizing the U-Net structure or adding new…

Image and Video Processing · Electrical Eng. & Systems 2025-09-15 Kunpeng Mao , Ruoyu Li , Junlong Cheng , Danmei Huang , Zhiping Song , ZeKui Liu

Deep learning models have shown promising performance for cell nucleus segmentation in the field of pathology image analysis. However, training a robust model from multiple domains remains a great challenge for cell nucleus segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Dawei Fan , Yifan Gao , Jiaming Yu , Yanping Chen , Wencheng Li , Chuancong Lin , Kaibin Li , Changcai Yang , Riqing Chen , Lifang Wei

The segmentation module which precisely outlines the nodules is a crucial step in a computer-aided diagnosis(CAD) system. The most challenging part of such a module is how to achieve high accuracy of the segmentation, especially for the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Xinliang Fu , Jiayin Zheng , Juanyun Mai , Yanbo Shao , Minghao Wang , Linyu Li , Zhaoqi Diao , Yulong Chen , Jianyu Xiao , Jian You , Airu Yin , Yang Yang , Xiangcheng Qiu , Jinsheng Tao , Bo Wang , Hua Ji

We present a deep learning strategy that enables, for the first time, contrast-agnostic semantic segmentation of completely unpreprocessed brain MRI scans, without requiring additional training or fine-tuning for new modalities. Classical…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Benjamin Billot , Douglas Greve , Koen Van Leemput , Bruce Fischl , Juan Eugenio Iglesias , Adrian V. Dalca

We propose an automatic preprocessing and ensemble learning for segmentation of cell images with low quality. It is difficult to capture cells with strong light. Therefore, the microscopic images of cells tend to have low image quality but…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Sota Kato , Kazuhiro Hotta

Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Wenhua Zhang , Sen Yang , Meiwei Luo , Chuan He , Yuchen Li , Jun Zhang , Xiyue Wang , Fang Wang

Image segmentation in total knee arthroplasty is crucial for precise preoperative planning and accurate implant positioning, leading to improved surgical outcomes and patient satisfaction. The biggest challenges of image segmentation in…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Viet Dung Nguyen , Michael T. LaCour , Richard D. Komistek

Fluorescence microscopy allows for a detailed inspection of cells, cellular networks, and anatomical landmarks by staining with a variety of carefully-selected markers visualized as color channels. Quantitative characterization of…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Alvaro Gomariz , Tiziano Portenier , Patrick M. Helbling , Stephan Isringhausen , Ute Suessbier , César Nombela-Arrieta , Orcun Goksel

Cell boundary information is crucial for analyzing cell behaviors from time-lapse microscopy videos. Existing supervised cell segmentation tools, such as ImageJ, require tuning various parameters and rely on restrictive assumptions about…

Applications · Statistics 2026-01-27 Laura Baracaldo , Blythe King , Haoran Yan , Yizi Lin , Nina Miolane , Mengyang Gu

The need for labour intensive pixel-wise annotation is a major limitation of many fully supervised learning methods for segmenting bioimages that can contain numerous object instances with thin separations. In this paper, we introduce a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Rihuan Ke , Aurélie Bugeau , Nicolas Papadakis , Peter Schuetz , Carola-Bibiane Schönlieb

Recent trends in cell segmentation have shifted towards universal models to handle diverse cell morphologies and imaging modalities. However, for continuously emerging cell types and imaging techniques, these models still require hundreds…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Peilin Zhou , Bo Du , Yongchao Xu

Medical image registration is crucial for various clinical and research applications including disease diagnosis or treatment planning which require alignment of images from different modalities, time points, or subjects. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Ahsan Raza Siyal , Markus Haltmeier , Ruth Steiger , Malik Galijasevic , Elke Ruth Gizewski , Astrid Ellen Grams

Semantic segmentation of brain tumours is a fundamental task in medical image analysis that can help clinicians in diagnosing the patient and tracking the progression of any malignant entities. Accurate segmentation of brain lesions is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Aditya Kasliwal , Sankarshanaa Sagaram , Laven Srivastava , Pratinav Seth , Adil Khan

Manual segmentation of medical images (e.g., segmenting tumors in CT scans) is a high-effort task that can be accelerated with machine learning techniques. However, selecting the right segmentation approach depends on the evaluation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

Segmentation of skin lesions is considered as an important step in computer aided diagnosis (CAD) for automated melanoma diagnosis. In recent years, segmentation methods based on fully convolutional networks (FCN) have achieved great…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Lei Bi , Dagan Feng , Jinman Kim

Analysis of microscopy images can provide insight into many biological processes. One particularly challenging problem is cell nuclear segmentation in highly anisotropic and noisy 3D image data. Manually localizing and segmenting each and…

Computer Vision and Pattern Recognition · Computer Science 2013-09-18 Christian Widmer , Philipp Drewe , Xinghua Lou , Shefali Umrania , Stephanie Heinrich , Gunnar Rätsch