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Multiplex tissue immunostaining is a technology of growing relevance as it can capture in situ the complex interactions existing between the elements of the tumor microenvironment. The existence and availability of large, annotated image…

Computer Vision and Pattern Recognition · Computer Science 2021-03-09 Daniel Jiménez-Sánchez , Mikel Ariz , Carlos Ortiz-de-Solórzano

An optical microscopic examination of thinly cut stained tissue on glass slides prepared from a FFPE tissue blocks is the gold standard for tissue diagnostics. In addition, the diagnostic abilities and expertise of any pathologist is…

Generating realistic tissue images with annotations is a challenging task that is important in many computational histopathology applications. Synthetically generated images and annotations are valuable for training and evaluating…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Srijay Deshpande , Fayyaz Minhas , Nasir Rajpoot

Artificial intelligence (AI), machine learning, and deep learning (DL) methods are becoming increasingly important in the field of biomedical image analysis. However, to exploit the full potential of such methods, a representative number of…

Synthetic generation of three-dimensional cell models from histopathological images aims to enhance understanding of cell mutation, and progression of cancer, necessary for clinical assessment and optimal treatment. Classical reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Yoav Alon , Xiang Yu , Huiyu Zhou

The rise of In-Context Learning (ICL) for universal medical image segmentation has introduced an unprecedented demand for large-scale, diverse datasets for training, exacerbating the long-standing problem of data scarcity. While data…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Jiesi Hu , Yanwu Yang , Zhiyu Ye , Chenfei Ye , Hanyang Peng , Jianfeng Cao , Ting Ma

Generative models capable of capturing nuanced clinical features in medical images hold great promise for facilitating clinical data sharing, enhancing rare disease datasets, and efficiently synthesizing annotated medical images at scale.…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 Shenghuan Sun , Gregory M. Goldgof , Atul Butte , Ahmed M. Alaa

Artificial intelligence and machine learning techniques have the promise to revolutionize the field of digital pathology. However, these models demand considerable amounts of data, while the availability of unbiased training data is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Nati Daniel , Eliel Aknin , Ariel Larey , Yoni Peretz , Guy Sela , Yael Fisher , Yonatan Savir

Despite significant progress on current state-of-the-art image generation models, synthesis of document images containing multiple and complex object layouts is a challenging task. This paper presents a novel approach, called DocSynth, to…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Sanket Biswas , Pau Riba , Josep Lladós , Umapada Pal

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

In multi-class histopathology nuclei analysis tasks, the lack of training data becomes a main bottleneck for the performance of learning-based methods. To tackle this challenge, previous methods have utilized generative models to increase…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Seonghui Min , Hyun-Jic Oh , Won-Ki Jeong

Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make…

Automatic thin-prep cytologic test (TCT) screening can assist pathologists in finding cervical abnormality towards accurate and efficient cervical cancer diagnosis. Current automatic TCT screening systems mostly involve abnormal cervical…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Zhenrong Shen , Manman Fei , Xin Wang , Jiangdong Cai , Sheng Wang , Lichi Zhang , Qian Wang

In recent years, deep learning (DL) has shown great potential in the field of dermatological image analysis. However, existing datasets in this domain have significant limitations, including a small number of image samples, limited disease…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Ashish Sinha , Jeremy Kawahara , Arezou Pakzad , Kumar Abhishek , Matthieu Ruthven , Enjie Ghorbel , Anis Kacem , Djamila Aouada , Ghassan Hamarneh

Synthetic images can be used for the development and evaluation of deep learning algorithms in the context of limited availability of data. In the field of computational pathology, where histology images are large in size and visual context…

Image and Video Processing · Electrical Eng. & Systems 2021-03-29 Srijay Deshpande , Fayyaz Minhas , Simon Graham , Nasir Rajpoot

Automation in medical imaging is quite challenging due to the unavailability of annotated datasets and the scarcity of domain experts. In recent years, deep learning techniques have solved some complex medical imaging tasks like disease…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Soumyajyoti Dey , Sukanta Chakraborty , Utso Guha Roy , Nibaran Das

Pseudo-healthy synthesis is the task of creating a subject-specific `healthy' image from a pathological one. Such images can be helpful in tasks such as anomaly detection and understanding changes induced by pathology and disease. In this…

Image and Video Processing · Electrical Eng. & Systems 2021-06-21 Tian Xia , Agisilaos Chartsias , Sotirios A. Tsaftaris

AI for cancer detection encounters the bottleneck of data scarcity, annotation difficulty, and low prevalence of early tumors. Tumor synthesis seeks to create artificial tumors in medical images, which can greatly diversify the data and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Yuxiang Lai , Xiaoxi Chen , Angtian Wang , Alan Yuille , Zongwei Zhou

The performance of medical image analysis systems is constrained by the quantity of high-quality image annotations. Such systems require data to be annotated by experts with years of training, especially when diagnostic decisions are…

Computer Vision and Pattern Recognition · Computer Science 2019-02-08 Siqi Liu , Eli Gibson , Sasa Grbic , Zhoubing Xu , Arnaud Arindra Adiyoso Setio , Jie Yang , Bogdan Georgescu , Dorin Comaniciu

Deep Learning (DL) models have been successfully applied to many applications including biomedical cell segmentation and classification in histological images. These models require large amounts of annotated data which might not always be…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Roberto Basla , Loris Giulivi , Luca Magri , Giacomo Boracchi
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