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Related papers: SVSBI: Sequence-based virtual screening of biomole…

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Recent advancements in Vision Language Models (VLMs) have demonstrated remarkable promise in generating visually grounded responses. However, their application in the medical domain is hindered by unique challenges. For instance, most VLMs…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Lingxiao Luo , Bingda Tang , Xuanzhong Chen , Rong Han , Ting Chen

The need for efficient computational screening of molecular candidates that possess desired properties frequently arises in various scientific and engineering problems, including drug discovery and materials design. However, the large size…

Optimization and Control · Mathematics 2023-01-05 Hyun-Myung Woo , Xiaoning Qian , Li Tan , Shantenu Jha , Francis J. Alexander , Edward R. Dougherty , Byung-Jun Yoon

Machine learning is capable of discriminating phases of matter, and finding associated phase transitions, directly from large data sets of raw state configurations. In the context of condensed matter physics, most progress in the field of…

Statistical Mechanics · Physics 2017-12-06 Pedro Ponte , Roger G. Melko

We describe a framework for interactive molecular dynamics in a multiuser virtual reality environment, combining rigorous cloud-mounted physical atomistic simulation with commodity virtual reality hardware, which we have made accessible to…

Computational protein-protein interaction (PPI) prediction techniques can contribute greatly in reducing time, cost and false-positive interactions compared to experimental approaches. Sequence is one of the key and primary information of…

Machine Learning · Computer Science 2022-03-29 Soumyadeep Debnath , Ayatullah Faruk Mollah

Variance-based sensitivity methods can provide insights into large computational models. We present a novel application of sensitivity analysis to the Biomass Scenario Model (BSM) a large and complex system dynamics model of the developing…

Applications · Statistics 2018-03-29 Daniel Inman , Laura J. Vimmerstedt , Brian Bush , Dana Stright , Steve Peterson

Semantic segmentation of Very High Resolution (VHR) remote sensing images is a fundamental task for many applications. However, large variations in the scales of objects in those VHR images pose a challenge for performing accurate semantic…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Yuanzhi Cai , Lei Fan , Yuan Fang

As the demand for immersive 3D content grows, the need for intuitive and efficient interaction methods becomes paramount. Current techniques for physically manipulating 3D content within Virtual Reality (VR) often face significant…

Virtual screening (VS) is a critical component of modern drug discovery, yet most existing methods--whether physics-based or deep learning-based--are developed around holo protein structures with known ligand-bound pockets. Consequently,…

Machine Learning · Computer Science 2025-10-31 Wenyu Zhu , Jianhui Wang , Bowen Gao , Yinjun Jia , Haichuan Tan , Ya-Qin Zhang , Wei-Ying Ma , Yanyan Lan

How to properly model the inter-frame relation within the video sequence is an important but unsolved challenge for video restoration (VR). In this work, we propose an unsupervised flow-aligned sequence-to-sequence model (S2SVR) to address…

Computer Vision and Pattern Recognition · Computer Science 2022-06-17 Jing Lin , Xiaowan Hu , Yuanhao Cai , Haoqian Wang , Youliang Yan , Xueyi Zou , Yulun Zhang , Luc Van Gool

Semantic scene completion (SSC) requires an accurate understanding of the geometric and semantic relationships between the objects in the 3D scene for reasoning the occluded objects. The popular SSC methods voxelize the 3D objects, allowing…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Haotian Dong , Enhui Ma , Lubo Wang , Miaohui Wang , Wuyuan Xie , Qing Guo , Ping Li , Lingyu Liang , Kairui Yang , Di Lin

Many everyday mobile manipulation tasks require precise interaction with small objects, such as grasping a knob to open a cabinet or pressing a light switch. In this paper, we develop Servoing with Vision Models (SVM), a closed-loop…

Robotics · Computer Science 2025-10-14 Arjun Gupta , Rishik Sathua , Saurabh Gupta

Ligand-based virtual screening (VS) is an essential step in drug discovery that evaluates large chemical libraries to identify compounds that potentially bind to a therapeutic target. However, VS faces three major challenges: class…

Machine Learning · Computer Science 2026-01-22 Xin Wang , Yu Wang , Yunchao Liu , Jens Meiler , Tyler Derr

Predicting drug-target interaction (DTI) is critical in the drug discovery process. Despite remarkable advances in recent DTI models through the integration of representations from diverse drug and target encoders, such models often…

Quantitative Methods · Quantitative Biology 2025-09-30 Zhaohan Meng , Zaiqiao Meng , Ke Yuan , Iadh Ounis

Accurately delineating the visual pathway (VP) is crucial for understanding the human visual system and diagnosing related disorders. Exploring multi-parametric MR imaging data has been identified as an important way to delineate VP.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Alou Diakite , Cheng Li , Lei Xie , Yuanjing Feng , Ruoyou Wu , Jianzhong He , Hairong Zheng , Shanshan Wang

We introduce S$^2$VS, a video similarity learning approach with self-supervision. Self-Supervised Learning (SSL) is typically used to train deep models on a proxy task so as to have strong transferability on target tasks after fine-tuning.…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Giorgos Kordopatis-Zilos , Giorgos Tolias , Christos Tzelepis , Ioannis Kompatsiaris , Ioannis Patras , Symeon Papadopoulos

The recent surge in high-quality visual instruction tuning samples from closed-source vision-language models (VLMs) such as GPT-4V has accelerated the release of open-source VLMs across various model sizes. However, scaling VLMs to improve…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Byung-Kwan Lee , Ryo Hachiuma , Yu-Chiang Frank Wang , Yong Man Ro , Yueh-Hua Wu

In content-based video retrieval (CBVR), dealing with large-scale collections, efficiency is as important as accuracy; thus, several video-level feature-based studies have actively been conducted. Nevertheless, owing to the severe…

Computer Vision and Pattern Recognition · Computer Science 2023-12-20 Won Jo , Geuntaek Lim , Gwangjin Lee , Hyunwoo Kim , Byungsoo Ko , Yukyung Choi

This work presents a machine learning approach based on support vector machines (SVMs) for quantum entanglement detection. Particularly, we focus in bipartite systems of dimensions 3x3, 4x4, and 5x5, where the positive partial transpose…

Simulation-based inference (SBI) is emerging as a new statistical paradigm for addressing complex scientific inference problems. By leveraging the representational power of deep neural networks, SBI can extract the most informative…

Instrumentation and Methods for Astrophysics · Physics 2025-10-17 Huifang Lyu , James Alvey , Noemi Anau Montel , Mauro Pieroni , Christoph Weniger
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