English
Related papers

Related papers: Digitized-Counterdiabatic Quantum Algorithm for Pr…

200 papers

Molecular docking plays a pivotal role in drug discovery and precision medicine, enabling us to understand protein functions and advance novel therapeutics. Here, we introduce a potential alternative solution to this problem, the…

Quantum Physics · Physics 2024-05-17 Qi-Ming Ding , Yi-Ming Huang , Xiao Yuan

Gate-based universal quantum computers form a rapidly evolving field of quantum computing hardware technology. In previous work, we presented a quantum algorithm for lattice protein folding on a cubic lattice, tailored for quantum…

Quantum Physics · Physics 2018-11-01 Mark Fingerhuth , Tomáš Babej , Christopher Ing

Integer factorization is a computational problem of fundamental importance in cybersecurity and secure communications, as its difficulty form the basis of modern public-key cryptography. While Shor's algorithm can solve this problem…

Quantum Physics · Physics 2025-11-18 Felip Pellicer

Utilizing counterdiabatic (CD) driving - aiming at suppression of diabatic transition - in digitized adiabatic evolution have garnered immense interest in quantum protocols and algorithms. However, improving the approximate CD terms with a…

Quantum Physics · Physics 2022-11-10 Dan Sun , Pranav Chandarana , Zi-Hua Xin , Xi Chen

This paper presents strategies to improve the performance of digitized counterdiabatic quantum optimization algorithms by cooptimizing gate sequences, algorithm parameters, and qubit mapping. Demonstrations on near-term quantum devices…

Quantum Physics · Physics 2024-09-18 Yanjun Ji , Kathrin F. Koenig , Ilia Polian

Combinatorial optimization plays a crucial role in many industrial applications. While classical computing often struggles with complex instances, quantum optimization emerges as a promising alternative. Here, we present an enhanced…

Branch-and-bound algorithms effectively solve combinatorial optimization problems, relying on the relaxation of the objective function to obtain tight lower bounds. While this is straightforward for convex objective functions, higher-order…

Protein folding processes are a vital aspect of molecular biology that is hard to simulate with conventional computers. Quantum algorithms have been proven superior for certain problems and may help tackle this complex life science…

Quantum Physics · Physics 2024-09-11 Hanna Linn , Isak Brundin , Laura García-Álvarez , Göran Johansson

Adiabatic quantum computers can solve difficult optimization problems (e.g., the quadratic unconstrained binary optimization problem), and they seem well suited to train machine learning models. In this paper, we describe an adiabatic…

Adiabatic quantum computing (AQC) started as an approach to solving optimization problems, and has evolved into an important universal alternative to the standard circuit model of quantum computing, with deep connections to both classical…

Quantum Physics · Physics 2018-02-05 Tameem Albash , Daniel A. Lidar

Quantum information processing is likely to have far-reaching impact in the field of artificial intelligence. While the race to build an error-corrected quantum computer is ongoing, noisy, intermediate-scale quantum (NISQ) devices provide…

Quantum adiabatic optimization seeks to solve combinatorial problems using quantum dynamics, requiring the Hamiltonian of the system to align with the problem of interest. However, these Hamiltonians are often incompatible with the native…

An adiabatic quantum algorithm is essentially given by three elements: An initial Hamiltonian with known ground state, a problem Hamiltonian whose ground state corresponds to the solution of the given problem and an evolution schedule such…

Quantum Physics · Physics 2019-09-17 Davide Pastorello , Enrico Blanzieri

Predicting the 3D structure of proteins is one of the most important problems in current biochemical research. In this article, we explain how to combine recent deep learning advances with the well known technique of quantum walks applied…

Quantum Physics · Physics 2022-03-10 P A M Casares , Roberto Campos , M A Martin-Delgado

Protein folding, which dictates the protein structure from its amino acid sequence, is half a century old problem of biology. The function of the protein correlates with its structure, emphasizing the need of understanding protein folding…

Quantum Physics · Physics 2025-01-03 Jaya Vasavi P , Soham Bopardikar , Avinash D , Ashwini K , Kalyan Dasgupta , Sanjib Senapati

Quantum computing promises to efficiently and accurately solve many important problems in quantum chemistry which elude classical solvers, such as the electronic structure problem of highly correlated materials. Two leading methods in…

Quantum Physics · Physics 2025-12-17 Sean Thrasher , Ioannis Kolotouros , Julien Michel , Petros Wallden

We report the realization of a nuclear magnetic resonance computer with three quantum bits that simulates an adiabatic quantum optimization algorithm. Adiabatic quantum algorithms offer new insight into how quantum resources can be used to…

Quantum Physics · Physics 2007-05-23 Matthias Steffen , Wim van Dam , Tad Hogg , Greg Breyta , Isaac Chuang

Solving optimization tasks using variational quantum algorithms has emerged as a crucial application of the current noisy intermediate-scale quantum devices. However, these algorithms face several difficulties like finding suitable ansatz…

Quantum Physics · Physics 2022-06-22 Pranav Chandarana , Pablo S. Vieites , Narendra N. Hegade , Enrique Solano , Yue Ban , Xi Chen

We explore the potential application of quantum annealing to address the protein structure problem. To this end, we compare several proposed ab initio protein folding models for quantum computers and analyze their scaling and performance…

Quantum Physics · Physics 2026-04-27 Timon Scheiber , Matthias Heller , Andreas Giebel

We outline an algorithm for the Quantum Counting problem using Adiabatic Quantum Computation (AQC). We show that using local adiabatic evolution, a process in which the adiabatic procedure is performed at a variable rate, the problem is…

Quantum Physics · Physics 2014-06-02 Itay Hen