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The continuing advancement of memory technology has not only fueled a surge in performance, but also substantially exacerbate reliability challenges. Traditional solutions have primarily focused on improving the efficiency of protection…

Hardware Architecture · Computer Science 2025-09-09 Fan Li , Mimi Xie , Yanan Guo , Huize Li , Xin Xin

The nucleotide sequence representation of DNA can be inadequate for resolving protein-DNA binding sites and regulatory substrates, such as those involved in gene expression and horizontal gene transfer. Considering that sequence-like…

Genomics · Quantitative Biology 2020-07-30 Jan Zrimec

Memory controllers have used static page closure policies to decide whether a row should be left open, open-page policy, or closed immediately, close-page policy, after the row has been accessed. The appropriate choice for a particular…

Hardware Architecture · Computer Science 2015-09-15 Mohsen Ghasempour , Aamer Jaleel , Jim Garside , Mikel Luján

Analyzing large-scale performance logs from GPU profilers often requires terabytes of memory and hours of runtime, even for basic summaries. These constraints prevent timely insight and hinder the integration of performance analytics into…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-27 Ankur Lahiry , Ayush Pokharel , Seth Ockerman , Amal Gueroudji , Line Pouchard , Tanzima Z. Islam

DNA nanotechnology uses predictable interactions of nucleic acids to precisely engineer complex nanostructures. Characterizing these self-assembled structures at the single-structure level is crucial for validating their design and…

Biological Physics · Physics 2025-10-21 Wangwei Dong , Zezhou Liu , Ruiyao Liu , Deborah Kuchnir Fygenson , Walter Reisner

In large scale distributed storage systems (DSS) deployed in cloud computing, correlated failures resulting in simultaneous failure (or, unavailability) of blocks of nodes are common. In such scenarios, the stored data or a content of a…

Information Theory · Computer Science 2017-02-22 Gokhan Calis , O. Ozan Koyluoglu

DNA has been considered a promising medium for storing digital information. As an essential step in the DNA-based data storage workflow, coding algorithms are responsible to implement functions including bit-to-base transcoding, error…

Emerging Technologies · Computer Science 2023-03-31 Haoling Zhang , Zhaojun Lan , Wenwei Zhang , Xun Xu , Zhi Ping , Yiwei Zhang , Yue Shen

Neural Network (NN) accelerators with emerging ReRAM (resistive random access memory) technologies have been investigated as one of the promising solutions to address the \textit{memory wall} challenge, due to the unique capability of…

Emerging Technologies · Computer Science 2019-01-30 Yu Ji , Youyang Zhang , Xinfeng Xie , Shuangchen Li , Peiqi Wang , Xing Hu , Youhui Zhang , Yuan Xie

Genome annotation is an important issue in biology which has long been addressed with gene prediction methods and manual experiments requiring biological expertise. The expanding Next Generation Sequencing technologies and their enhanced…

Computation · Statistics 2013-07-02 Alice Cleynen , Michel Koskas , Emilie Lebarbier , Guillem Rigaill , Stephane Robin

Deep neural networks (DNN) have become significant applications in both cloud-server and edge devices. Meanwhile, the growing number of DNNs on those platforms raises the need to execute multiple DNNs on the same device. This paper proposes…

Hardware Architecture · Computer Science 2023-02-22 Midia Reshadi , David Gregg

In this paper, we consider the outer channel for DNA-based data storage. When transmitting over the outer channel, each DNA string is treated as a unit/symbol that would be either correctly received, or erased, or corrupted by uniformly…

Information Theory · Computer Science 2025-09-23 Xuan He , Yi Ding , Kui Cai , Guanghui Song , Bin Dai , Xiaohu Tang

DNA-coated colloids can crystallize into a multitude of lattices, ranging from face-centered cubic to diamond and thereby contribute to our understanding of crystallization and open avenues to producing structures with useful photonic…

Soft Condensed Matter · Physics 2026-04-17 Pepijn G. Moerman , Huang Fang , Thomas E. Videbæk , W. Benjamin Rogers , Rebecca Schulman

Erasure codes provide a storage efficient alternative to replication based redundancy in (networked) storage systems. They however entail high communication overhead for maintenance, when some of the encoded fragments are lost and need to…

Distributed, Parallel, and Cluster Computing · Computer Science 2010-11-24 Frederique Oggier , Anwitaman Datta

Designing RNA molecules has garnered recent interest in medicine, synthetic biology, biotechnology and bioinformatics since many functional RNA molecules were shown to be involved in regulatory processes for transcription, epigenetics and…

Machine Learning · Computer Science 2019-04-15 Frederic Runge , Danny Stoll , Stefan Falkner , Frank Hutter

Much sequential data exhibits highly non-uniform information distribution. This cannot be correctly modeled by traditional Long Short-Term Memory (LSTM). To address that, recent works have extended LSTM by adding more activations between…

Neural and Evolutionary Computing · Computer Science 2019-03-07 Yifeng Zhang , Ka-Ho Chow , S. -H. Gary Chan

High-performance clusters and datacenters pose increasingly demanding requirements on storage systems. If these systems do not operate at scale, applications are doomed to become I/O bound and waste compute cycles. To accelerate the data…

Networking and Internet Architecture · Computer Science 2022-06-22 Salvatore Di Girolamo , Daniele De Sensi , Konstantin Taranov , Milos Malesevic , Maciej Besta , Timo Schneider , Severin Kistler , Torsten Hoefler

The emergence of Deep Neural Networks (DNNs) in mission- and safety-critical applications brings their reliability to the front. High performance demands of DNNs require the use of specialized hardware accelerators. Systolic array…

Hardware Architecture · Computer Science 2025-11-05 Natalia Cherezova , Artur Jutman , Maksim Jenihhin

Deep neural networks (DNNs) have been widely deployed across diverse domains such as computer vision and natural language processing. However, the impressive accomplishments of DNNs have been realized alongside extensive computational…

Machine Learning · Computer Science 2023-11-28 Chuangtao Chen , Grace Li Zhang , Xunzhao Yin , Cheng Zhuo , Ulf Schlichtmann , Bing Li

String sorting is an important part of tasks such as building index data structures. Unfortunately, current string sorting algorithms do not scale to massively parallel distributed-memory machines since they either have latency (at least)…

Data Structures and Algorithms · Computer Science 2024-04-26 Florian Kurpicz , Pascal Mehnert , Peter Sanders , Matthias Schimek

In hardware-aware Differentiable Neural Architecture Search (DNAS), it is challenging to compute gradients of hardware metrics to perform architecture search. Existing works rely on linear approximations with limited support to customized…

Machine Learning · Computer Science 2021-11-25 Qian Jiang , Xiaofan Zhang , Deming Chen , Minh N. Do , Raymond A. Yeh