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DNA storage is now being considered as a new archival storage method for its durability and high information density, but still facing some challenges like high costs and low throughput. By reducing sequencing sample size for decoding…

Information Theory · Computer Science 2025-04-22 Ruiying Cao , Xin Chen

Since the birth of computer and networks, fuelled by pervasive computing and ubiquitous connectivity, the amount of data stored and transmitted has exponentially grown through the years. Due to this demand, new solutions for storing data…

The configurable building blocks of current FPGAs -- Logic blocks (LBs), Digital Signal Processing (DSP) slices, and Block RAMs (BRAMs) -- make them efficient hardware accelerators for the rapid-changing world of Deep Learning (DL).…

Hardware Architecture · Computer Science 2021-10-01 Aman Arora , Bagus Hanindhito , Lizy K. John

In this paper, we propose a novel iterative encoding algorithm for DNA storage to satisfy both the GC balance and run-length constraints using a greedy algorithm. DNA strands with run-length more than three and the GC balance ratio far from…

Information Theory · Computer Science 2023-01-04 Seong-Joon Park , Yongwoo Lee , Jong-Seon No

We consider error-correcting coding for deoxyribonucleic acid (DNA)-based storage using nanopore sequencing. We model the DNA storage channel as a sampling noise channel where the input data is chunked into $M$ short DNA strands, which are…

Information Theory · Computer Science 2024-06-21 Lorenz Welter , Roman Sokolovskii , Thomas Heinis , Antonia Wachter-Zeh , Eirik Rosnes , Alexandre Graell i Amat

We present an efficient lock-free algorithm for parallel accessible hash tables with open addressing, which promises more robust performance and reliability than conventional lock-based implementations. ``Lock-free'' means that it is…

Distributed, Parallel, and Cluster Computing · Computer Science 2007-05-23 Hui Gao , Jan Friso Groote , Wim H. Hesselink

As machine learning applications continue to evolve, the demand for efficient hardware accelerators, specifically tailored for deep neural networks (DNNs), becomes increasingly vital. In this paper, we propose a configurable memory…

Hardware Architecture · Computer Science 2024-04-25 Oliver Bause , Paul Palomero Bernardo , Oliver Bringmann

In the emerging field of DNA storage, data is encoded as DNA sequences and stored. The data is read out again by sequencing the stored DNA. Nanopore sequencing is a new sequencing technology that has many advantages over other methods; in…

Information Theory · Computer Science 2021-02-04 Reyna Hulett , Shubham Chandak , Mary Wootters

The yearly global production of data is growing exponentially, outpacing the capacity of existing storage media, such as tape and disk, and surpassing our ability to store it. DNA storage - the representation of arbitrary information as…

Quantitative Methods · Quantitative Biology 2023-10-04 Thomas Heinis , Roman Sokolovskii , Jamie J. Alnasir

A method for encoding information in DNA sequences is described. The method is based on the precision-resolution framework, and is aimed to work in conjunction with a recently suggested terminator-free template independent DNA synthesis…

Information Theory · Computer Science 2020-05-14 Siddharth Jain , Farzad Farnoud , Moshe Schwartz , Jehoshua Bruck

Storing digital data in synthetic DNA faces challenges in ensuring data reliability in the presence of edit errors--deletions, insertions, and substitutions--that occur randomly during various stages of the storage process. Current…

Information Theory · Computer Science 2025-09-11 Serge Kas Hanna

DNA is an attractive medium for digital data storage. When data is stored on DNA, errors occur, which makes error-correcting coding techniques critical for reliable DNA data storage. To reduce the errors, a common technique is to include…

Information Theory · Computer Science 2024-06-27 Franziska Weindel , Andreas L. Gimpel , Robert N. Grass , Reinhard Heckel

This paper introduces OPTIMUM-DERAM, a highly consistent, scalable, secure, and decentralized shared memory solution. Traditional distributed shared memory implementations offer multi-object support by multi-threading a single object memory…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-21 Nicolas Nicolaou , Kishori M. Konwar , Moritz Grundei , Aleksandr Bezobchuk , Muriel Médard , Sriram Vishwanath

In this paper, we study the Random Access Problem in DNA storage, which addresses the challenge of retrieving a specific information strand from a DNA-based storage system. In this framework, the data is represented by $k$ information…

Information Theory · Computer Science 2025-08-26 Avital Boruchovsky , Ohad Elishco , Ryan Gabrys , Anina Gruica , Itzhak Tamo , Eitan Yaakobi

Owing to its longevity and enormous information density, DNA, the molecule encoding biological information, has emerged as a promising archival storage medium. However, due to technological constraints, data can only be written onto many…

Emerging Technologies · Computer Science 2018-03-12 Reinhard Heckel , Gediminas Mikutis , Robert N. Grass

Byte-addressable persistent memories (PM) has finally made their way into production. An important and pressing problem that follows is how to deploy them in existing datacenters. One viable approach is to attach PM as self-contained…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-08 Shin-Yeh Tsai , Yiying Zhang

Due to its longevity and enormous information density, DNA is an attractive medium for archival storage. In this work, we study the fundamental limits and tradeoffs of DNA-based storage systems under a simple model, motivated by current…

Information Theory · Computer Science 2017-05-16 Reinhard Heckel , Ilan Shomorony , Kannan Ramchandran , David N. C. Tse

DNA is an attractive candidate for data storage. Its millennial durability and nanometer scale offer exceptional data density and longevity. Its relevance to medical applications also drives advances in DNA-related biotechnology. To protect…

Information Theory · Computer Science 2025-11-25 Yu-Ting Lin , Hsin-Po Wang , Venkatesan Guruswami

Persistent memory (PM) is an emerging class of storage technology that combines the benefits of DRAM and SSD. This characteristic inspires research on persistent objects in PM with fine-grained concurrency control. Among such objects,…

Programming Languages · Computer Science 2022-03-16 Kyeongmin Cho , Seungmin Jeon , Jeehoon Kang

We propose coding techniques that limit the length of homopolymers runs, ensure the GC-content constraint, and are capable of correcting a single edit error in strands of nucleotides in DNA-based data storage systems. In particular, for…

Information Theory · Computer Science 2020-01-10 Tuan Thanh Nguyen , Kui Cai , Kees A. Schouhamer Immink , Han Mao Kiah