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The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

Machine Learning · Computer Science 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe

This technical report introduces a Named Clinical Entity Recognition Benchmark for evaluating language models in healthcare, addressing the crucial natural language processing (NLP) task of extracting structured information from clinical…

Automating medical reports for retinal images requires a sophisticated blend of visual pattern recognition and deep clinical knowledge. Current Large Vision-Language Models (LVLMs) often struggle in specialized medical fields where data is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nagur Shareef Shaik , Teja Krishna Cherukuri , Dong Hye Ye

An accurate differential diagnosis (DDx) is essential for patient care, shaping therapeutic decisions and influencing outcomes. Recently, Large Language Models (LLMs) have emerged as promising tools to support this process by generating a…

Artificial Intelligence · Computer Science 2025-10-07 Seungseop Lim , Gibaeg Kim , Hyunkyung Lee , Wooseok Han , Jean Seo , Jaehyo Yoo , Eunho Yang

With the rising global burden of chronic diseases and the multimodal and heterogeneous clinical data (medical imaging, free-text recordings, wearable sensor streams, etc.), there is an urgent need for a unified multimodal AI framework that…

Artificial Intelligence · Computer Science 2025-09-24 Dingxin Lu , Shurui Wu , Xinyi Huang

Electronic health records (EHR) contain narrative notes that provide extensive details on the medical condition and management of patients. Natural language processing (NLP) of clinical notes can use observed frequencies of clinical terms…

Computation and Language · Computer Science 2023-07-04 Bryan Cai , Sihang Zeng , Yucong Lin , Zheng Yuan , Doudou Zhou , Lu Tian

Explainable Artificial Intelligence (AI) in the form of an interpretable and semiautomatic approach to stage grading ocular pathologies such as Diabetic retinopathy, Hypertensive retinopathy, and other retinopathies on the backdrop of major…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Ayushi Raj Bhatt , Rajkumar Vaghashiya , Meghna Kulkarni , Dr Prakash Kamaraj

Computer-aided diagnosis (CAD), a vibrant medical imaging research field, is expanding quickly. Because errors in medical diagnostic systems might lead to seriously misleading medical treatments, major efforts have been made in recent years…

Machine Learning · Computer Science 2023-08-04 Farzaneh Tajidini , Mohammad-Javad Kheiri

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods. In this paper, we propose MDNet to establish a direct multimodal…

Computer Vision and Pattern Recognition · Computer Science 2017-07-11 Zizhao Zhang , Yuanpu Xie , Fuyong Xing , Mason McGough , Lin Yang

Pretraining has proven to be a powerful technique in natural language processing (NLP), exhibiting remarkable success in various NLP downstream tasks. However, in the medical domain, existing pretrained models on electronic health records…

Artificial Intelligence · Computer Science 2023-10-23 Xiaochen Wang , Junyu Luo , Jiaqi Wang , Ziyi Yin , Suhan Cui , Yuan Zhong , Yaqing Wang , Fenglong Ma

The emergence of artificial intelligence (AI), particularly deep learning (DL), has marked a new era in the realm of ophthalmology, offering transformative potential for the diagnosis and treatment of posterior segment eye diseases. This…

Image and Video Processing · Electrical Eng. & Systems 2025-01-09 Duy M. H. Nguyen , Hasan Md Tusfiqur Alam , Tai Nguyen , Devansh Srivastav , Hans-Juergen Profitlich , Ngan Le , Daniel Sonntag

Building trustworthy clinical AI systems requires not only accurate predictions but also transparent, biologically grounded explanations. We present \texttt{DiagnoLLM}, a hybrid framework that integrates Bayesian deconvolution, eQTL-guided…

Artificial Intelligence · Computer Science 2025-11-18 Bowen Xu , Xinyue Zeng , Jiazhen Hu , Tuo Wang , Adithya Kulkarni

In medical image analysis, the expertise scarcity and the high cost of data annotation limits the development of large artificial intelligence models. This paper investigates the potential of transfer learning with pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Jiajin Zhang , Ge Wang , Mannudeep K. Kalra , Pingkun Yan

Background: Lung disease is a significant health issue, particularly in children and elderly individuals. It often results from lung infections and is one of the leading causes of mortality in children. Globally, lung-related diseases claim…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Muhammad Ahmad , Sardar Usman , Ildar Batyrshin , Muhammad Muzammil , K. Sajid , M. Hasnain , Muhammad Jalal , Grigori Sidorov

Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

Computation and Language · Computer Science 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

In this paper, we consider the problem of disease diagnosis. Unlike the conventional learning paradigm that treats labels independently, we propose a knowledge-enhanced framework, that enables training visual representation with the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-28 Chaoyi Wu , Xiaoman Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

The medical domain is vast and diverse, with many existing embedding models focused on general healthcare applications. However, these models often struggle to capture a deep understanding of diseases due to their broad generalization…

Computation and Language · Computer Science 2024-12-23 Salman Faroz

Existing research has shown the potential of classifying Alzheimers Disease (AD) from eye-tracking (ET) data with classifiers that rely on task-specific engineered features. In this paper, we investigate whether we can improve on existing…

Computer Vision and Pattern Recognition · Computer Science 2023-09-25 Harshinee Sriram , Cristina Conati , Thalia Field

Accurate diagnosis of ophthalmic diseases relies heavily on the interpretation of multimodal ophthalmic images, a process often time-consuming and expertise-dependent. Visual Question Answering (VQA) presents a potential interdisciplinary…

Image and Video Processing · Electrical Eng. & Systems 2024-10-23 Xiaolan Chen , Ruoyu Chen , Pusheng Xu , Weiyi Zhang , Xianwen Shang , Mingguang He , Danli Shi