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Kernel two-sample tests have been widely used for multivariate data to test equality of distributions. However, existing tests based on mapping distributions into a reproducing kernel Hilbert space mainly target specific alternatives and do…

Methodology · Statistics 2023-11-21 Hoseung Song , Hao Chen

We introduce a method---called Fisher exact scanning (FES)---for testing and identifying variable dependency that generalizes Fisher's exact test on $2\times 2$ contingency tables to $R\times C$ contingency tables and continuous sample…

Methodology · Statistics 2017-05-03 Li Ma , Jialiang Mao

Meta-analysis seeks to combine the results of several experiments in order to improve the accuracy of decisions. It is common to use a test for homogeneity to determine if the results of the several experiments are sufficiently similar to…

Methodology · Statistics 2009-08-01 Elena Kulinskaya , Michael B. Dollinger , Kirsten Bjørkestøl

The Behrens-Fisher problem concerns testing the equality of the means of two normal populations with possibly different variances. The null hypothesis in this problem induces a statistical model for which the likelihood function may have…

Statistics Theory · Mathematics 2010-03-04 Mathias Drton

A common task in high-throughput biology is to test for differences in means between two samples across thousands of features (e.g., genes or proteins), often with only a handful of replicates per sample. Moderated t-tests handle this…

Methodology · Statistics 2025-10-02 Wanyi Ling , Wufang Hong , Nikolaos Ignatiadis

The two-sample homogeneity testing problem is fundamental in statistics and becomes particularly challenging in high dimensions, where classical tests can suffer substantial power loss. We develop a learning-assisted procedure based on the…

Methodology · Statistics 2026-01-30 Xiaoyu Hu , Zhenhua Lin

In this paper, we propose a new test for testing the equality of two population covariance matrices in the ultra-high dimensional setting that the dimension is much larger than the sizes of both of the two samples. Our proposed methodology…

Methodology · Statistics 2023-12-19 Xiucai Ding , Yichen Hu , Zhenggang Wang

Evolve and resequence studies provide a popular approach to simulate evolution in the lab and explore its genetic basis. In this context, the chi-square test, Fishers exact test, as well as the Cochran-Mantel-Haenszel test are commonly used…

Applications · Statistics 2019-02-22 Kerstin Spitzer , Marta Pelizzola , Andreas Futschik

This paper proposes a novel test method for high-dimensional mean testing regard for the temporal dependent data. Comparison to existing methods, we establish the asymptotic normality of the test statistic without relying on restrictive…

Methodology · Statistics 2025-12-01 Yuchen Hu , Xiaoyi Wang , Long Feng

This paper deals with two-sample tests for functional time series data, which have become widely available in conjunction with the advent of modern complex observation systems. Here, particular interest is in evaluating whether two sets of…

Statistics Theory · Mathematics 2019-09-16 Alexander Aue , Holger Dette , Gregory Rice

Two-sample tests evaluate whether two samples are realizations of the same distribution (the null hypothesis) or two different distributions (the alternative hypothesis). We consider a new setting for this problem where sample features are…

Machine Learning · Computer Science 2022-07-20 Weizhi Li , Gautam Dasarathy , Karthikeyan Natesan Ramamurthy , Visar Berisha

For in vivo research experiments with small sample sizes and available historical data, we propose a sequential Bayesian method for the Behrens-Fisher problem. We consider it as a model choice question with two models in competition: one…

Statistics Theory · Mathematics 2016-11-22 Antoine Barbieri , Jean-Michel Marin , Karine Florin

Since the two seminal papers by Fisher (1915, 1921) were published, the test under a fixed value correlation coefficient null hypothesis for the bivariate normal distribution constitutes an important statistical problem. In the framework of…

Statistics Theory · Mathematics 2022-09-27 María Jaenada , Elena Castilla , Nirian Martín , Leandro Pardo

Missing data is a common issue in many biomedical studies. Under a paired design, some subjects may have missing values in either one or both of the conditions due to loss of follow-up, insufficient biological samples, etc. Such partially…

We propose a two-sample mean test based on the Bayes factor with non-informative priors, specifically designed for scenarios where the dimension $p$ grows with the sample size $n$ with a linear rate $p/n \to c_1 \in (0, \infty)$. We…

Methodology · Statistics 2026-04-07 Daojiang He , Suren Xu , Jing Zhou

We investigate Gaussian Universality for data distributions generated via diffusion models. By Gaussian Universality we mean that the test error of a generalized linear model $f(\mathbf{W})$ trained for a classification task on the…

Machine Learning · Statistics 2025-09-30 Reza Ghane , Anthony Bao , Danil Akhtiamov , Babak Hassibi

In this paper, we investigate hypothesis testing for the linear combination of mean vectors across multiple populations through the method of random integration. We have established the asymptotic distributions of the test statistics under…

Applications · Statistics 2024-03-13 Jianghao Li , Shizhe Hong , Zhenzhen Niu , Zhidong Bai

We study the problem of testing the equivalence of functional parameters (such as the mean or variance function) in the two sample functional data problem. In contrast to previous work, which reduces the functional problem to a multiple…

Statistics Theory · Mathematics 2020-04-28 Holger Dette , Kevin Kokot

We propose a two-sample test for high-dimensional means that requires neither distributional nor correlational assumptions, besides some weak conditions on the moments and tail properties of the elements in the random vectors. This…

Methodology · Statistics 2019-04-17 Kaijie Xue , Fang Yao

We consider three problems in high-dimensional Gaussian linear mixed models. Without any assumptions on the design for the fixed effects, we construct an asymptotic $F$-statistic for testing whether a collection of random effects is zero,…

Statistics Theory · Mathematics 2019-07-30 Michael Law , Ya'acov Ritov