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A comprehensive assessment of retinal health demands reliable and precise methods to measure localized blood perfusion. Despite considerable advancements in imaging techniques, such as indocyanine green and fluorescein angiography, along…

Medical Physics · Physics 2024-03-15 Michael Atlan

From the earth's crust to the human brain, remitted waves are used for sensing and imaging in a diverse range of diffusive media. Separating the source and detector increases the penetration depth of remitted light, yet rapidly decreases…

Discrete delta functions define the limits of attainable spatial resolution for all imaging systems. Here we construct broad, multi-dimensional discrete functions that replicate closely the action of a Dirac delta function under aperiodic…

Image and Video Processing · Electrical Eng. & Systems 2020-09-01 I. D. Svalbe , D. M. Paganin , T. C. Petersen

Poor access to eye care is a major global challenge that could be ameliorated by low-cost, portable, and easy-to-use diagnostic technologies. Diffuser-based imaging has the potential to enable inexpensive, compact optical systems that can…

Medical Physics · Physics 2020-06-23 Yunzhe Li , Gregory N. McKay , Nicholas J. Durr , Lei Tian

Laser Doppler holography was introduced as a full-field imaging technique to measure blood flow in the retina and choroid with an as yet unrivaled temporal resolution. We here investigate separating the different contributions to the power…

Medical Physics · Physics 2021-06-02 Léo Puyo , Michel Paques , Mathias Fink , José-Alain Sahel , Michael Atlan

Unidirectional optical systems enable selective control of light through asymmetric processing of radiation, effectively transmitting light in one direction while blocking unwanted propagation in the opposite direction. Here, we introduce a…

Optics · Physics 2025-03-21 Yuhang Li , Tianyi Gan , Jingxi Li , Mona Jarrahi , Aydogan Ozcan

The Maxwellian display presents always-focused images to the viewer, alleviating the vergence-accommodation conflict (VAC) in near-eye displays (NEDs). However, the limited eyebox of the typical Maxwellian display prevents it from wider…

Optics · Physics 2021-06-14 Shijie Zhang , Juan Liu , Zhiqi Zhang

The inverse design of optical metasurfaces is a rapidly emerging field that has already shown great promise in miniaturizing conventional optics as well as developing completely new optical functionalities. Such a design process relies on…

Optics · Physics 2020-08-26 Maksym V. Zhelyeznyakov , Steven L. Brunton , Arka Majumdar

Intracavity laser-based systems are emerging as key enablers for next-generation wireless communications, positioning, and wireless power transfer (WPT). Distributed coupled-cavity laser (DCCL) systems, as a representative configuration,…

Optics · Physics 2025-07-30 Mingqing Liu , Hao Deng , Iman Tavakkolnia , Qingwen Liu , Bin He , Harald Haas

Precise modeling of extended sources is a central challenge in modern optical engineering, laser physics, and computational lithography. Unlike ideal point sources or completely incoherent thermal radiation sources, real-world light sources…

Optics · Physics 2025-12-09 Rongqi Shang , Donglin Ma

Wide field-of-view imaging of fast processes in a microscope requires high light intensities motivating the use of lasers as light sources. However, due to their long spatial coherence length lasers are inappropriate for such applications…

Instrumentation and Detectors · Physics 2018-05-23 Tim Stangner , Hanqing Zhang , Tobias Dahlberg , Krister Wiklund , Magnus Andersson

This publication extends the HoloTile framework to three dimensions, introducing the ability to generate arbitrary dynamic patterns composed of extended depth-of-field non-diffractive beamlets with theoretically 100% diffraction efficiency.…

Optics · Physics 2024-06-03 Andreas Erik Gejl Madsen , Jesper Glückstad

In radar systems, high resolution in the Doppler dimension is important for detecting slow-moving targets as it allows for more distinct separation between these targets and clutter, or stationary objects. However, achieving sufficient…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Denisa Qosja , Kilian Barth , Simon Wagner

Laser Doppler holography (LDH) is a full-field blood flow imaging technique able to reveal human retinal and choroidal blood flow with high temporal resolution. We here report on using LDH in the anterior segment of the eye without making…

3D surface reconstruction is essential across applications of virtual reality, robotics, and mobile scanning. However, RGB-based reconstruction often fails in low-texture, low-light, and low-albedo scenes. Handheld LiDARs, now common on…

Image and Video Processing · Electrical Eng. & Systems 2024-12-02 Nikhil Behari , Aaron Young , Siddharth Somasundaram , Tzofi Klinghoffer , Akshat Dave , Ramesh Raskar

Laser Doppler holography is a planar blood flow imaging technique recently introduced in ophthalmology to image human retinal and choroidal blood flow non-invasively. Here we present a digital method based on the Doppler spectrum asymmetry…

Medical Physics · Physics 2021-08-10 Léo Puyo , Michel Paques , Michael Atlan

The diffractive nature of light has limited optics and photonics to operate at scales much larger than the wavelength of light. The major challenge in scaling-down integrated photonics is how to mold the light flow below diffraction-limit…

Optics · Physics 2007-12-27 Seunghoon Han , Yi Xiong , Dentcho Genov , Zhaowei Liu , Guy Bartal , Xiang Zhang

The penetration depth of photoacoustic imaging in biological tissues has been fundamentally limited by the strong optical attenuation when light is delivered externally through the tissue surface. To address this issue, we previously…

Medical Physics · Physics 2021-02-24 Mucong Li , Tri Vu , Georgy Sankii , Brenton Winship , Kohldon Boydston , Russell Terry , Pei Zhong , Junjie Yao

Confining light illumination in the three dimensions of space is a challenge for various applications. Among these, optogenetic methods developed for live experiments in cell biology would benefit from such a localized illumination as it…

The eye offers a unique opportunity for non-invasive exploration of cardiovascular diseases. Optical angiography in the retina requires sensitive measurements, which hinders conventional full-field laser Doppler imaging schemes. To overcome…

Medical Physics · Physics 2018-09-18 L. Puyo , M. Paques , M. Fink , J. -A. Sahel , M. Atlan
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