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We present a hybrid method that performs the complete parcellation of the cerebral cortex of an individual, based on the connectivity information of the white matter fibers from a whole-brain tractography dataset. The method consists of…

Neurons and Cognition · Quantitative Biology 2020-02-24 Narciso López-López , Andrea Vázquez , Cyril Poupon , Jean-François Mangin , Pamela Guevara

Studies in recent years have demonstrated that neural organization and structure impact an individual's ability to perform a given task. Specifically, individuals with greater neural efficiency have been shown to outperform those with less…

We exploit altered patterns in brain functional connectivity as features for automatic discriminative analysis of neuropsychiatric patients. Deep learning methods have been introduced to functional network classification only very recently…

Machine Learning · Computer Science 2020-04-27 Chun-Ren Phang , Chee-Ming Ting , Fuad Noman , Hernando Ombao

Mapping the brain imaging data to networks, where each node represents a specific area of the brain, has enabled an objective graph-theoretic analysis of human connectome. However, the latent structure on higher-order connections remains…

Neurons and Cognition · Quantitative Biology 2019-04-09 Bosiljka Tadic , Miroslav Andjelkovic , Roderick Melnik

There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

Methodology · Statistics 2016-03-22 Jichun Xie , Jian Kang

We propose a new framework, called Hierarchical Multi-resolution Mesh Networks (HMMNs), which establishes a set of brain networks at multiple time resolutions of fMRI signal to represent the underlying cognitive process. The suggested…

Neural and Evolutionary Computing · Computer Science 2017-01-13 Itir Onal Ertugrul , Mete Ozay , Fatos Tunay Yarman Vural

We develop the hierarchical cluster coherence (HCC) method for brain signals, a procedure for characterizing connectivity in a network by clustering nodes or groups of channels that display high level of coordination as measured by…

Applications · Statistics 2017-11-21 Carolina Euan , Ying Sun , Hernando Ombao

Understanding the human brain remains the Holy Grail in biomedical science, and arguably in all of the sciences. Our brains represent the most complex systems in the world (and some contend the universe) comprising nearly one hundred…

Quantitative Methods · Quantitative Biology 2016-02-03 Sean L. Simpson , Paul J. Laurienti

Objective: Schizophrenia seriously affects the quality of life. To date, both simple (linear discriminant analysis) and complex (deep neural network) machine learning methods have been utilized to identify schizophrenia based on functional…

Machine Learning · Computer Science 2021-05-11 Tian Wang , Anastasios Bezerianos , Andrzej Cichocki , Junhua Li

Brain networks from functional MRI have advanced our understanding of cortical activity and its disruption in neurodegenerative disorders. Recent work has increasingly focused on dynamic (time-varying) brain networks that capture both…

Neurons and Cognition · Quantitative Biology 2026-04-14 Nicolas Rubido , Venia Batziou , Marwan Fuad , Vesna Vuksanovic

Functional connectivity network (FCN) data from functional magnetic resonance imaging (fMRI) is increasingly used for the diagnoses of brain disorders. However, state-of-the-art studies used to build the FCN using a single brain…

Image and Video Processing · Electrical Eng. & Systems 2022-09-26 Mianxin Liu , Han Zhang , Feng Shi , Dinggang Shen

The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

Small-World Networks (SWNs) represent a fundamental model for the comprehension of many complex man-made and biological networks. In the central nervous system, SWN models have been shown to fit well both anatomical and functional maps at…

For long it has been known that specific patterns of folding are necessary for an optimally functioning brain. For instance, lissencephaly and polymicrogyria can lead to severe mental retardation, short life expectancy, epileptic seizures,…

Biological Physics · Physics 2020-04-03 Lucas da Costa Campos , Raphael Hornung , Gerhard Gompper , Jens Elgeti , Svenja Caspers

Autism spectrum disorder (ASD) affects the brain connectivity at different levels. Nonetheless, non-invasively distinguishing such effects using magnetic resonance imaging (MRI) remains very challenging to machine learning diagnostic…

Machine Learning · Computer Science 2020-04-29 Ismail Bilgen , Goktug Guvercin , Islem Rekik

Modularity is an important topological attribute for functional brain networks. Recent studies have reported that modularity of functional networks varies not only across individuals being related to demographics and cognitive performance,…

Neurons and Cognition · Quantitative Biology 2018-10-05 Makoto Fukushima , Richard F. Betzel , Ye He , Marcel A. de Reus , Martijn P. van den Heuvel , Xi-Nian Zuo , Olaf Sporns

The cerebral cortex is composed of multiple cortical areas that exert a wide variety of brain functions. Although human brain neurons are genetically and areally mosaic, the three-dimensional structural differences between neurons in…

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

Applications · Statistics 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

To understand the biological characteristics of neurological disorders with functional connectivity (FC), recent studies have widely utilized deep learning-based models to identify the disease and conducted post-hoc analyses via explainable…

Machine Learning · Computer Science 2023-10-09 Eunsong Kang , Da-woon Heo , Jiwon Lee , Heung-Il Suk
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