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Empirical studies over the past two decades have supported the hypothesis that schizophrenia is characterized by altered connectivity patterns in functional brain networks. These alterations have been proposed as genetically-mediated…

Neurons and Cognition · Quantitative Biology 2013-06-28 Felix Siebenhuhner , Shennan A. Weiss , Richard Coppola , Daniel R. Weinberger , Danielle S. Bassett

Schizophrenia (SZ) is a brain disorder leading to detached mind's normally integrated processes. Hence, the exploration of the symptoms in relation to functional connectivity (FC) had great relevance in the field. FC can be investigated on…

Neurons and Cognition · Quantitative Biology 2026-04-08 Davide Coluzzi , Giuseppe Baselli

Network neuroscience shed some light on the functional and structural modifications occurring to the brain associated with the phenomenology of schizophrenia. In particular, resting-state functional networks have helped our understanding of…

Neurons and Cognition · Quantitative Biology 2021-04-30 Rossana Mastrandrea , Fabrizio Piras , Andrea Gabrielli , Nerisa Banaj , Guido Caldarelli , Gianfranco Spalletta , Tommaso Gili

Modularity plays an important role in brain networks' architecture and influences its dynamics and the ability to integrate and segregate different modules of cerebral regions. Alterations in community structure are associated with several…

Neurons and Cognition · Quantitative Biology 2018-05-14 M. Cinelli , I. Echegoyen , M. Oliveira , S. Orellana , T. Gili

Structure entails function and thus a structural description of the brain will help to understand its function and may provide insights into many properties of brain systems, from their robustness and recovery from damage, to their dynamics…

Neurons and Cognition · Quantitative Biology 2008-08-27 Marcus Kaiser , Robert Martin , Peter Andras , Malcolm P. Young

We study the topological properties of functional connectivity patterns among cortical areas in the frequency domain. The cortical networks were estimated from high-resolution EEG recordings in a group of spinal cord injured patients and in…

Quantitative Methods · Quantitative Biology 2015-05-13 Roberta Sinatra , Fabrizio De Vico Fallani , Laura Astolfi , Fabio Babiloni , Febo Cincotti , Vito Latora , Donatella Mattia

We have reported nanometer-scale three-dimensional studies of brain networks of schizophrenia cases and found that their neurites are thin and tortuous compared to healthy controls. This suggests that connections between distal neurons are…

Image and Video Processing · Electrical Eng. & Systems 2022-04-04 Ryuta Mizutani , Senta Noguchi , Rino Saiga , Yuichi Yamashita , Mitsuhiro Miyashita , Makoto Arai , Masanari Itokawa

This study aims to investigate topological organization of cortical thickness and functional networks by cortical lobes. First, I demonstrated modular organization of these networks by the cortical surface frontal, temporal, parietal and…

Neurons and Cognition · Quantitative Biology 2025-05-27 Vesna Vuksanović

Brain Functional Networks (BFNs), graph theoretical models of brain activity data, provide a systems perspective of complex functional connectivity within the brain. Neurological disorders are known to have basis in abnormal functional…

Quantitative Methods · Quantitative Biology 2016-08-30 Megha Singh , Rahul Badhwar , Ganesh Bagler

Brain connectome analysis commonly compresses high-resolution brain scans (typically composed of millions of voxels) down to only hundreds of regions of interest (ROIs) by averaging within-ROI signals. This huge dimension reduction improves…

Methodology · Statistics 2025-03-25 Tong Lu , Yuan Zhang , Peter Kochunov , Elliot Hong , Shuo Chen

Functional magnetic resonance imaging recordings in the resting-state (RS) from the human brain are characterized by spontaneous low-frequency fluctuations in the blood oxygenation level dependent signal that reveal functional connectivity…

Neurons and Cognition · Quantitative Biology 2013-02-21 Iwo Jerzy Bohr , Eva Kenny , Andrew Blamire , John T. O'Brien , Alan J. Thomas , Jonathan Richardson , Marcus Kaiser

The organization of the connectivity between mammalian cortical areas has become a major subject of study, because of its important role in scaffolding the macroscopic aspects of animal behavior and intelligence. In this study we present a…

Neurons and Cognition · Quantitative Biology 2007-05-23 Luciano da F Costa , Marcus Kaiser , Claus C Hilgetag

Detecting and evaluating regions of brain under various circumstances is one of the most interesting topics in computational neuroscience. However, the majority of the studies on detecting communities of a functional connectivity network of…

Social and Information Networks · Computer Science 2018-06-04 Keivan Hassani Monfared , Kris Vasudevan , Jordan S. Farrell , G. Campbell Teskey

In recent years, network analyses have been used to evaluate brain reorganization following stroke. However, many studies have often focused on single topological scales, leading to an incomplete model of how focal brain lesions affect…

Neurons and Cognition · Quantitative Biology 2014-09-10 Fabrizio De Vico Fallani , Floriana Pichiorri , Giovanni Morone , Marco Molinari , Fabio Babiloni , Febo Cincotti , Donatella Mattia

Several studies have used structural correlation networks, derived from anatomical covariance of brain regions, to analyze neurologic changes associated with multiple sclerosis, schizophrenia and breast cancer [1][2]. Graph-theoretical…

Quantitative Methods · Quantitative Biology 2019-04-25 Muhammad Usman Sadiq , Diana Svaldi , Trey Shenk , Evan Breedlove , Victoria Poole , Greg Tamer , Kausar Abbas , Thomas Talavage

Functional connectivity (FC) has been widely used to study brain network interactions underlying the emerging cognition and behavior of an individual. FC is usually defined as the correlation or partial correlation between brain regions.…

Applications · Statistics 2020-10-27 Gemeng Zhang , Aiying Zhang , Biao Cai , Zhuozhuo Tu , Vince D. Calhoun , Yu-Ping Wang

Functional Magnetic Resonance Imaging (fMRI) is commonly utilized to study human brain activity, including abnormal functional properties related to neurodegenerative diseases. This study aims to investigate the differences in the…

Neurons and Cognition · Quantitative Biology 2023-05-17 Yongcheng Yao

Anxiety includes behavioural, physiological, and subjective components that do not always align, and it remains unclear whether these dimensions are supported by distinct intrinsic brain networks. Guided by the two-system framework, we…

Neurons and Cognition · Quantitative Biology 2026-05-04 Shruti Kinger , Mrinmoy Chakrabarty

We use methods from computational algebraic topology to study functional brain networks, in which nodes represent brain regions and weighted edges encode the similarity of fMRI time series from each region. With these tools, which allow one…

Quantitative Methods · Quantitative Biology 2020-08-27 Bernadette J. Stolz , Tegan Emerson , Satu Nahkuri , Mason A. Porter , Heather A. Harrington

The human brain has a complex, intricate functional architecture. While many studies primarily emphasize pairwise interactions, delving into high-order associations is crucial for a comprehensive understanding of how functional brain…

Neurons and Cognition · Quantitative Biology 2023-10-30 Qiang Li , Vince D. Calhoun , Adithya Ram Ballem , Shujian Yu , Jesus Malo , Armin Iraji
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