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We investigate how elimination of variables can affect the asymptotic dynamics and phenotype control of Boolean networks. In particular, we look at the impact on minimal trap spaces, and identify a structural condition that guarantees their…

Discrete Mathematics · Computer Science 2024-08-14 Elisa Tonello , Loïc Paulevé

We consider the problem of learning Bayesian networks (BNs) from complete discrete data. This problem of discrete optimisation is formulated as an integer program (IP). We describe the various steps we have taken to allow efficient solving…

Artificial Intelligence · Computer Science 2015-03-24 Mark Bartlett , James Cussens

Boolean networks are a popular modeling framework in computational biology to capture the dynamics of molecular networks, such as gene regulatory networks. It has been observed that many published models of such networks are defined by…

Molecular Networks · Quantitative Biology 2019-12-06 Elijah Paul , Gleb Pogudin , William Qin , Reinhard Laubenbacher

Bayesian inference for neural networks, or Bayesian deep learning, has the potential to provide well-calibrated predictions with quantified uncertainty and robustness. However, the main hurdle for Bayesian deep learning is its computational…

Machine Learning · Statistics 2023-09-07 Sanket Jantre , Nathan M. Urban , Xiaoning Qian , Byung-Jun Yoon

This paper studies the minimum control node set problem for Boolean networks (BNs) with degree constraints. The main contribution is to derive the nontrivial lower and upper bounds on the size of the minimum control node set through…

Systems and Control · Electrical Eng. & Systems 2026-03-03 Liangjie Sun , Wai-Ki Ching , Tatsuya Akutsu

Deep neural networks have been successfully deployed in a wide variety of applications including computer vision and speech recognition. However, computational and storage complexity of these models has forced the majority of computations…

Machine Learning · Computer Science 2018-08-28 Mahdi Nazemi , Ghasem Pasandi , Massoud Pedram

We study the problem of certifying the robustness of Bayesian neural networks (BNNs) to adversarial input perturbations. Given a compact set of input points $T \subseteq \mathbb{R}^m$ and a set of output points $S \subseteq \mathbb{R}^n$,…

Machine Learning · Computer Science 2023-06-26 Matthew Wicker , Andrea Patane , Luca Laurenti , Marta Kwiatkowska

A Boolean network is a discrete dynamical system operating on vectors of Boolean variables. The action of a Boolean network can be conveniently expressed as a system of Boolean update functions, computing the new values for each component…

Formal Languages and Automata Theory · Computer Science 2023-03-02 Artiom Alhazov , Vincent Ferrari-Dominguez , Rudolf Freund , Nicolas Glade , Sergiu Ivanov

A recently introduced measure of Boolean functions complexity--disjunc\-tive complexity (DC)--is compared with other complexity measures: the space complexity of streaming algorithms and the complexity of nondeterministic branching programs…

Computational Complexity · Computer Science 2025-04-01 Nikita Ivanov , Alexander Rubtsov , Michael Vyalyi

The success of deep convolutional neural network (CNN) in computer vision especially image classification problems requests a new information theory for function of image, instead of image itself. In this article, after establishing a deep…

Machine Learning · Computer Science 2017-10-17 Ya-Hui Zhang

Bayesian networks are probabilistic graphical models with a wide range of application areas including gene regulatory networks inference, risk analysis and image processing. Learning the structure of a Bayesian network (BNSL) from discrete…

Artificial Intelligence · Computer Science 2021-06-24 Fulya Trösser , Simon de Givry , George Katsirelos

The neural basis of probabilistic computations remains elusive, even amidst growing evidence that humans and other animals track their uncertainty. Recent work has proposed that probabilistic representations arise naturally in…

Neurons and Cognition · Quantitative Biology 2025-12-18 Ishan Kalburge , Máté Lengyel

It is known that describing or calculating the conditional probabilities of multiple events is exponentially expensive. In this work, Bayesian tensor network (BTN) is proposed to efficiently capture the conditional probabilities of multiple…

Machine Learning · Statistics 2020-01-08 Shi-Ju Ran

Recent works have demonstrated that neural networks exhibit extreme simplicity bias(SB). That is, they learn only the simplest features to solve a task at hand, even in the presence of other, more robust but more complex features. Due to…

Machine Learning · Computer Science 2023-02-02 Depen Morwani , Jatin Batra , Prateek Jain , Praneeth Netrapalli

Although probabilistic inference in a general Bayesian belief network is an NP-hard problem, computation time for inference can be reduced in most practical cases by exploiting domain knowledge and by making approximations in the knowledge…

Artificial Intelligence · Computer Science 2016-11-04 Alexander V. Kozlov , Jaswinder Pal Singh

Boolean networks are a general model of interacting entities, with applications to biological phenomena such as gene regulation. Attractors play a central role, and the schedule of entities update is a priori unknown. This article presents…

Discrete Mathematics · Computer Science 2020-01-22 Florian Bridoux , Caroline Gaze-Maillot , Kévin Perrot , Sylvain Sené

We are interested in assigning a pre-specified number of nodes as leaders in order to minimize the mean-square deviation from consensus in stochastically forced networks. This problem arises in several applications including control of…

Optimization and Control · Mathematics 2014-12-11 Fu Lin , Makan Fardad , Mihailo R. Jovanović

We investigate how classifiers for Boolean networks (BNs) can be constructed and modified under constraints. A typical constraint is to observe only states in attractors or even more specifically steady states of BNs. Steady states of BNs…

Commutative Algebra · Mathematics 2021-08-20 Robert Schwieger , Matías R. Bender , Heike Siebert , Christian Haase

Measures of circuit complexity are usually analyzed to ensure the computation of Boolean functions with economy and efficiency. One of these measures is energy complexity, which is related to the number of gates that output true in a…

Computational Complexity · Computer Science 2022-10-14 Janio Carlos Nascimento Silva , Uéverton S. Souza

This paper describes a purely functional library for computing level-$p$-complexity of Boolean functions, and applies it to two-level iterated majority. Boolean functions are simply functions from $n$ bits to one bit, and they can describe…

Programming Languages · Computer Science 2023-12-13 Julia Jansson , Patrik Jansson