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Extreme learning machine (ELM) is an extremely fast learning method and has a powerful performance for pattern recognition tasks proven by enormous researches and engineers. However, its good generalization ability is built on large numbers…

Machine Learning · Computer Science 2015-02-05 Wentao Zhu , Jun Miao , Laiyun Qing

Can we use spiking neural networks (SNN) as generative models of multi-neuronal recordings, while taking into account that most neurons are unobserved? Modeling the unobserved neurons with large pools of hidden spiking neurons leads to…

Neurons and Cognition · Quantitative Biology 2023-01-10 Shuqi Wang , Valentin Schmutz , Guillaume Bellec , Wulfram Gerstner

This paper aims to quantitatively explain rationales of each prediction that is made by a pre-trained convolutional neural network (CNN). We propose to learn a decision tree, which clarifies the specific reason for each prediction made by…

Computer Vision and Pattern Recognition · Computer Science 2019-02-26 Quanshi Zhang , Yu Yang , Haotian Ma , Ying Nian Wu

The robustness and anomaly detection capability of neural networks are crucial topics for their safe adoption in the real-world. Moreover, the over-parameterization of recent networks comes with high computational costs and raises questions…

Machine Learning · Computer Science 2022-07-12 Morgane Ayle , Bertrand Charpentier , John Rachwan , Daniel Zügner , Simon Geisler , Stephan Günnemann

Many analyses in particle and nuclear physics use simulations to infer fundamental, effective, or phenomenological parameters of the underlying physics models. When the inference is performed with unfolded cross sections, the observables…

Data Analysis, Statistics and Probability · Physics 2024-09-19 Owen Long , Benjamin Nachman

A major challenge in both neuroscience and machine learning is the development of useful tools for understanding complex information processing systems. One such tool is probes, i.e., supervised models that relate features of interest to…

Machine Learning · Computer Science 2021-04-19 Anna A. Ivanova , John Hewitt , Noga Zaslavsky

The performance of machine learning models is determined by the quality of their learned features. They should be invariant under irrelevant data variation but sensitive to task-relevant details. To visualize whether this is the case, we…

Machine Learning · Computer Science 2026-03-24 Armand Rousselot , Joran Wendebourg , Ullrich Köthe

Despite the recent success of neural network models in mimicking animal performance on visual perceptual tasks, critics worry that these models fail to illuminate brain function. We take it that a central approach to explanation in systems…

Neurons and Cognition · Quantitative Biology 2021-04-13 Rosa Cao , Daniel Yamins

This paper applies a deep convolutional/highway MLP framework to classify genomic sequences on the transcription factor binding site task. To make the model understandable, we propose an optimization driven strategy to extract "motifs", or…

Machine Learning · Computer Science 2016-06-03 Jack Lanchantin , Ritambhara Singh , Zeming Lin , Yanjun Qi

Just like weights, bias terms are the learnable parameters of many popular machine learning models, including neural networks. Biases are thought to enhance the representational power of neural networks, enabling them to solve a variety of…

Computer Vision and Pattern Recognition · Computer Science 2023-05-30 Chuqin Geng , Xiaojie Xu , Haolin Ye , Xujie Si

In recent years, several machine learning approaches have been proposed to predict gene expression and epigenetic signals from the DNA sequence alone. These models are often used to deduce, and, to some extent, assess putative new…

Genomics · Quantitative Biology 2023-04-26 Laurent Bréhélin

While deep neural networks (DNNs) are used for prediction, inference on DNN-estimated subject-specific means for categorical or exponential family outcomes remains underexplored. We address this by proposing a DNN estimator under…

Machine Learning · Statistics 2026-03-18 Xuran Meng , Yi Li

Sequence modelling approaches for epigenetic profile prediction have recently expanded in terms of sequence length, model size, and profile diversity. However, current models cannot infer on many experimentally feasible tissue and assay…

Genomics · Quantitative Biology 2023-08-24 Jacob Deasy , Ron Schwessinger , Ferran Gonzalez , Stephen Young , Kim Branson

Our formal understanding of the inductive bias that drives the success of convolutional networks on computer vision tasks is limited. In particular, it is unclear what makes hypotheses spaces born from convolution and pooling operations so…

Neural and Evolutionary Computing · Computer Science 2017-04-19 Nadav Cohen , Amnon Shashua

Multilayer networks have seen a resurgence under the umbrella of deep learning. Current deep learning algorithms train the layers of the network sequentially, improving algorithmic performance as well as providing some regularization. We…

Machine Learning · Computer Science 2016-02-22 Ke Wu , Malik Magdon-Ismail

Evaluation of generative models is mostly based on the comparison between the estimated distribution and the ground truth distribution in a certain feature space. To embed samples into informative features, previous works often use…

Machine Learning · Computer Science 2022-12-15 Junghyuk Lee , Jun-Hyuk Kim , Jong-Seok Lee

A very important topic in systems biology is developing statistical methods that automatically find causal relations in gene regulatory networks with no prior knowledge of causal connectivity. Many methods have been developed for time…

Machine Learning · Statistics 2012-08-22 Shohei Shimizu

Deep directed generative models have attracted much attention recently due to their expressive representation power and the ability of ancestral sampling. One major difficulty of learning directed models with many latent variables is the…

Machine Learning · Computer Science 2015-06-16 Siqi Nie , Qiang Ji

A grand challenge in machine learning is the development of computational algorithms that match or outperform humans in perceptual inference tasks that are complicated by nuisance variation. For instance, visual object recognition involves…

Machine Learning · Statistics 2015-04-03 Ankit B. Patel , Tan Nguyen , Richard G. Baraniuk

The wide and rapid adoption of deep learning by practitioners brought unintended consequences in many situations such as in the infamous case of Google Photos' racist image recognition algorithm; thus, necessitated the utilization of the…

Machine Learning · Computer Science 2019-05-24 Mehmet Yigit Yildirim , Mert Ozer , Hasan Davulcu
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