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Recent work has shown that the structure of convolutional neural networks (CNNs) induces a strong prior that favors natural images. This prior, known as a deep image prior (DIP), is an effective regularizer in inverse problems such as image…
Small animal PET scanners require high spatial resolution and good sensitivity. To reconstruct high-resolution images in 3D-PET, iterative methods, such as OSEM, are superior to analytical reconstruction algorithms, although their high…
Reconstruction of PET images is an ill-posed inverse problem and often requires iterative algorithms to achieve good image quality for reliable clinical use in practice, at huge computational costs. In this paper, we consider the PET…
Low-dose Positron Emission Tomography (PET) reduces radiation exposure but suffers from severe noise and quantitative degradation. Diffusion-based denoising models achieve strong final reconstructions, yet their reverse trajectories are…
Unsupervised learning methods, such as Deep Image Prior (DIP), have shown great potential in tomographic imaging due to their training-data-free nature and high generalization capability. However, their reliance on numerous network…
Deep learning-based image enhancement methods face a fundamental trade-off between computational efficiency and representational capacity. For example, although a conventional three-dimensional Look-Up Table (3D LUT) can process a degraded…
Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…
Positron emission tomography (PET) is widely utilized for cancer detection due to its ability to visualize functional and biological processes in vivo. PET images are usually reconstructed from histogrammed raw data (sinograms) using…
Single-bed whole-body positron emission tomography based on resistive plate chamber detectors (RPC-PET) has been proposed for human studies, as a complementary resource to scintillator-based PET scanners. The purpose of this work is mainly…
Ill-posed inverse problems appear in many image processing applications, such as deblurring and super-resolution. In recent years, solutions that are based on deep Convolutional Neural Networks (CNNs) have shown great promise. Yet, most of…
Image deconvolution is the process of recovering convolutional degraded images, which is always a hard inverse problem because of its mathematically ill-posed property. On the success of the recently proposed deep image prior (DIP), we…
In the last decades, unsupervised deep learning based methods have caught researchers attention, since in many real applications, such as medical imaging, collecting a great amount of training examples is not always feasible. Moreover, the…
The inductive bias of the convolutional neural network (CNN) can be a strong prior for image restoration, which is known as the Deep Image Prior (DIP). Recently, DIP is utilized in unsupervised dynamic MRI reconstruction, which adopts a…
As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…
Reducing scan times, radiation dose, and enhancing image quality for lower-performance scanners, are critical in low-dose PET imaging. Deep learning techniques have been investigated for PET image denoising. However, existing models have…
Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…
Deep learning algorithms that rely on extensive training data are revolutionizing image recovery from ill-posed measurements. Training data is scarce in many imaging applications, including ultra-high-resolution imaging. The deep image…
Biological experiments based on organ-on-chips (OOCs) exploit light Time-Lapse Microscopy (TLM) for a direct observation of cell movement that is an observable signature of underlying biological processes. A high spatial resolution is…
Images from positron emission tomography (PET) provide metabolic information about the human body. They present, however, a spatial resolution that is limited by physical and instrumental factors often modeled by a blurring function. Since…
Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…