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In a multi-stage recommendation system, reranking plays a crucial role in modeling intra-list correlations among items. A key challenge lies in exploring optimal sequences within the combinatorial space of permutations. Recent research…

Information Retrieval · Computer Science 2025-10-30 Zhijie Lin , Zhuofeng Li , Chenglei Dai , Wentian Bao , Shuai Lin , Enyun Yu , Haoxiang Zhang , Liang Zhao

Quality control in industrial processes is increasingly making use of prior scientific knowledge, often encoded in physical models that require numerical approximation. Statistical prediction, and subsequent optimization, is key to ensuring…

Other Statistics · Statistics 2018-10-23 Antony Overstall , David Woods , Kieran Martin

Multistep returns, such as $n$-step returns and $\lambda$-returns, are commonly used to improve the sample efficiency of reinforcement learning (RL) methods. The variance of the multistep returns becomes the limiting factor in their length;…

Machine Learning · Computer Science 2025-12-23 Brett Daley , Martha White , Marlos C. Machado

Tree search-based methods have made significant progress in enhancing the code generation capabilities of large language models. However, due to the difficulty in effectively evaluating intermediate algorithmic steps and the inability to…

Artificial Intelligence · Computer Science 2025-12-18 Yuanyuan Lin , Xiangyu Ouyang , Teng Zhang , Kaixin Sui

The adoption of detailed mechanisms for chemical kinetics often poses two types of severe challenges: First, the number of degrees of freedom is large; and second, the dynamics is characterized by widely disparate time scales. As a result,…

Dynamical Systems · Mathematics 2025-10-01 Eliodoro Chiavazzo , C. William Gear , Carmeline J. Dsilva , Neta Rabin , Ioannis G. Kevrekidis

With recent advancements in large language models, methods like chain-of-thought prompting to elicit reasoning chains have been shown to improve results on reasoning tasks. However, tasks that require multiple steps of reasoning still pose…

Computation and Language · Computer Science 2023-12-13 Olga Golovneva , Sean O'Brien , Ramakanth Pasunuru , Tianlu Wang , Luke Zettlemoyer , Maryam Fazel-Zarandi , Asli Celikyilmaz

Recently, rectified flow (RF)-based models have achieved state-of-the-art performance in many areas for both the multi-step and one-step generation. However, only a few theoretical works analyze the discretization complexity of RF-based…

Machine Learning · Computer Science 2025-08-13 Ruofeng Yang , Zhaoyu Zhu , Bo Jiang , Cheng Chen , Shuai Li

Despite being the cornerstone of deep learning, backpropagation is criticized for its inherent sequentiality, which can limit the scalability of very deep models. Such models faced convergence issues due to vanishing gradient, later…

Machine Learning · Computer Science 2025-04-01 Erwan Fagnou , Paul Caillon , Blaise Delattre , Alexandre Allauzen

Efficient synthesis recipes are needed both to streamline the manufacturing of complex materials and to accelerate the realization of theoretically predicted materials. Oftentimes the solid-state synthesis of multicomponent oxides is…

Materials Science · Physics 2024-04-10 Jiadong Chen , Samuel R. Cross , Lincoln J. Miara , Jeong-Ju Cho , Yan Wang , Wenhao Sun

Recent advances in Chain-of-Thought (CoT) prompting have substantially improved the reasoning capabilities of Large Language Models (LLMs). However, these methods often suffer from overthinking, leading to unnecessarily lengthy or redundant…

Computation and Language · Computer Science 2025-06-13 Zhensheng Jin , Xinze Li , Yifan Ji , Chunyi Peng , Zhenghao Liu , Qi Shi , Yukun Yan , Shuo Wang , Furong Peng , Ge Yu

Models invoking the chemical master equation are used in many areas of science, and, hence, their simulation is of interest to many researchers. The complexity of the problems at hand often requires considerable computational power, so a…

Biological Physics · Physics 2016-03-02 Fabian Spill , Philip K. Maini , Helen Byrne

Early stage drug discovery and molecular design projects often follow iterative design-make-test cycles. The selection of which compounds to synthesize from all possible candidate compounds is a complex decision inherent to these design…

Quantitative Methods · Quantitative Biology 2025-03-19 Jenna C. Fromer , Alexandra D. Volkova , Connor W. Coley

Homologous gene shuffling between DNA promotes genetic diversity and is an important pathway for DNA repair. For this to occur, homologous genes need to find and recognize each other. However, despite its central role in homologous…

Biological Physics · Physics 2014-12-04 Dominic J. Lee , Aaron Wynveen , Tim Albrecht , Alexei A. Kornyshev

Metabolomics complements investigation of the genome, transcriptome, and proteome of an organism. Today, the vast majority of metabolites remain unknown, in particular for non-model organisms. Mass spectrometry is one of the predominant…

Quantitative Methods · Quantitative Biology 2013-07-31 Kai Dührkop , Marcus Ludwig , Marvin Meusel , Sebastian Böcker

Designing protein sequences that fold into a target 3D structure, known as protein inverse folding, is a fundamental challenge in protein engineering. While recent deep learning methods have achieved impressive performance by recovering…

Biomolecules · Quantitative Biology 2025-06-03 Mengdi Liu , Xiaoxue Cheng , Zhangyang Gao , Hong Chang , Cheng Tan , Shiguang Shan , Xilin Chen

Recent advances in embedding-based retrieval have enabled dense retrievers to serve as core infrastructure in many industrial systems, where a single retrieval backbone is often shared across multiple downstream applications. In such…

Information Retrieval · Computer Science 2026-04-21 Yunhan Li , Mingjie Xie , Zihan Gong , Zeyang Shi , Gengshen Wu , Min Yang

Multi-stage sensing is a novel concept that refers to a general class of spectrum sensing algorithms that divide the sensing process into a number of sequential stages. The number of sensing stages and the sensing technique per stage can be…

Performance · Computer Science 2012-08-30 Wesam Gabran , Przemysław Pawełczak , Danijela Čabrić

Organic synthesis is one of the key stumbling blocks in medicinal chemistry. A necessary yet unsolved step in planning synthesis is solving the forward problem: given reactants and reagents, predict the products. Similar to other work, we…

Chemical Physics · Physics 2019-09-13 Philippe Schwaller , Teodoro Laino , Théophile Gaudin , Peter Bolgar , Costas Bekas , Alpha A Lee

Metabolic heterogeneity is widely recognised as the next challenge in our understanding of non-genetic variation. A growing body of evidence suggests that metabolic heterogeneity may result from the inherent stochasticity of intracellular…

Molecular Networks · Quantitative Biology 2020-10-08 Mona K Tonn , Philipp Thomas , Mauricio Barahona , Diego A Oyarzún

Image reflection removal is crucial for restoring image quality. Distorted images can negatively impact tasks like object detection and image segmentation. In this paper, we present a novel approach for image reflection removal using a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Abdelrahman Elnenaey , Marwan Torki
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