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Approximate Bayesian Computation is widely used to infer the parameters of discrete-state continuous-time Markov networks. In this work, we focus on models that are governed by the Chemical Master Equation (the CME). Whilst originally…

Quantitative Methods · Quantitative Biology 2020-01-10 Christopher Lester

The optical depth to reionization, a key parameter of the $\Lambda$CDM model, can be computed within astrophysical frameworks for star formation by modeling the evolution of the intergalactic medium. Accurate evaluation of this parameter is…

Cosmology and Nongalactic Astrophysics · Physics 2025-03-17 Gaétan Facchinetti

We present two different approaches for parameter learning in several mixture models in one dimension. Our first approach uses complex-analytic methods and applies to Gaussian mixtures with shared variance, binomial mixtures with shared…

Machine Learning · Computer Science 2020-01-22 Akshay Krishnamurthy , Arya Mazumdar , Andrew McGregor , Soumyabrata Pal

We extensively describe our recently established "divide-and-conquer" semiclassical method [M. Ceotto, G. Di Liberto and R. Conte, Phys. Rev. Lett. 119, 010401 (2017)] and propose a new implementation of it to increase the accuracy of…

Chemical Physics · Physics 2018-01-15 Giovanni Di Liberto , Riccardo Conte , Michele Ceotto

The first-principles-based effective Hamiltonian scheme provides one of the most accurate modeling technique for large-scale structures, especially for ferroelectrics. However, the parameterization of the effective Hamiltonian is…

We present numerical upscaling techniques for a class of linear second-order self-adjoint elliptic partial differential operators (or their high-resolution finite element discretization). As prototypes for the application of our theory we…

Numerical Analysis · Mathematics 2014-09-11 Axel Malqvist , Daniel Peterseim

The parameterization of simulation-based models is a central yet laborious task in computational chemistry and physics, often driven by human intuition and manual iteration. Automating this task necessitates the definition of suitable…

For discretisations of hyperbolic conservation laws, mimicking properties of operators or solutions at the continuous (differential equation) level discretely has resulted in several successful methods. While well-posedness for nonlinear…

Numerical Analysis · Mathematics 2019-10-22 Hendrik Ranocha

We present a detailed numerical study of an alternative approach, named Quantum Non-Demolition Measurement (QNDM), to efficiently estimate the gradients or the Hessians of a quantum observable. This is a key step and a resource-demanding…

Quantum Physics · Physics 2025-04-02 Giovanni Minuto , Dario Melegari , Simone Caletti , Paolo Solinas

This paper explores the use of foundational large language models (LLMs) in hyperparameter optimization (HPO). Hyperparameters are critical in determining the effectiveness of machine learning models, yet their optimization often relies on…

Machine Learning · Computer Science 2024-11-12 Michael R. Zhang , Nishkrit Desai , Juhan Bae , Jonathan Lorraine , Jimmy Ba

Procedural material models have been gaining traction in many applications thanks to their flexibility, compactness, and easy editability. We explore the inverse rendering problem of procedural material parameter estimation from…

Graphics · Computer Science 2025-04-22 Yu Guo , Milos Hasan , Lingqi Yan , Shuang Zhao

Wave packet molecular dynamics (WPMD) has recently received a lot of attention as a computationally fast tool to study dynamical processes in warm dense matter beyond the Born-Oppenheimer approximation. These techniques, typically, employ…

Plasma Physics · Physics 2021-04-09 William A. Angermeier , Thomas G. White

Finite-context models (FCMs) are widely used for compressing symbolic sequences such as DNA, where predictive performance depends critically on the context length k and smoothing parameter {\alpha}. In practice, these hyperparameters are…

Machine Learning · Statistics 2026-03-23 José Contente , Ana Martins , Armando J. Pinho , Sónia Gouveia

Molecular mechanics (MM) potentials have long been a workhorse of computational chemistry. Leveraging accuracy and speed, these functional forms find use in a wide variety of applications in biomolecular modeling and drug discovery, from…

In this paper, we test and compare the performance of two different theoretical methods that use anti-Hermitian terms for modeling open quantum systems. It is, the non-Hermitian quantum mechanics method (NHQM) and the recent methodology…

Quantum Physics · Physics 2018-12-26 Santiago Echeverri-Arteaga , Herbert Vinck-Posada , Edgar A. Gómez

Ordinary differential equation (ODE) models are widely used to describe systems in many areas of science. To ensure these models provide accurate and interpretable representations of real-world dynamics, it is often necessary to infer…

Methodology · Statistics 2026-03-24 Selva Salimi , David J. Warne , Christopher Drovandi

This dissertation explores the topics of parameter estimation and model reduction in the context of quantum filtering. Chapters 2 and 3 provide a review of classical and quantum probability theory, stochastic calculus and filtering. Chapter…

Quantum Physics · Physics 2009-08-11 Bradley A. Chase

This is a technical report which explores the estimation methodologies on hyper-parameters in Markov Random Field and Gaussian Hidden Markov Random Field. In first section, we briefly investigate a theoretical framework on…

Machine Learning · Statistics 2017-11-22 Namjoon Suh

Phantom systems consisting of liposome suspensions are widely employed to investigate quantitative MRI parameters mimicking cellular membranes. The proper physical understanding of the measurement results, however, requires proper models…

Medical Physics · Physics 2024-09-02 Heiko Neeb , Felix Schyboll , Rona Shaharabani , Aviv A. Mezer , Oshrat Shtangel

Analytic first and second derivatives of the energy are developed for the fragment molecular orbital method interfaced with molecular mechanics in the electrostatic embedding scheme at the level of Hartree-Fock and density functional…

Chemical Physics · Physics 2020-05-19 Hiroya Nakata , Dmitri G. Fedorov
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