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The process of self-morphing in curved surfaces found in nature, such as with the growth of flowers and leaves, has generated interest in the study of self-morphing bilayers, which has been used in many soft robots or switchers. However,…

Numerical Analysis · Mathematics 2023-09-19 Junjie Song , Yixiong Feng , Zhaoxi Hong , Bingtao Hu , Jianrong Tan , Xiuju Song

Plasmodium of \emph{Physarum polycephalum} is a single huge (visible by naked eye) cell with myriad of nuclei. The plasmodium is a promising substrate for non-classical, nature-inspired, computing devices. It is capable for approximation of…

Robotics · Computer Science 2010-11-23 Andrew Adamatzky

Plasmodium stage of Physarum polycephalum behaves as a distributed dynamical pattern formation mechanism who's foraging and migration is influenced by local stimuli from a wide range of attractants and repellents. Complex protoplasmic tube…

Biological Physics · Physics 2012-04-10 Soichiro Tsuda , Jeff Jones , Andrew Adamatzky , Jonathan Mills

We experimentally derived a unique one-to-one mapping between a range of selected bioactive chemicals and patterns of oscillations of the slime mould's extacellular electrical potential.

Emerging Technologies · Computer Science 2013-12-17 James G. H. Whiting , Ben P. J. de Lacy Costello , Andrew Adamatzky

Plasmodium of true slime mold, Physarum polycephalum, is an amoeboid organism, which spreads with developing tubular network structure and crawls on two-dimensional plane with oscillating the cell thickness. The plasmodium transforms its…

Adaptation and Self-Organizing Systems · Physics 2009-04-10 Yuki Kagawa , Atsuko Takamatsu

Very simple organisms, such as the single-celled amoeboid slime mould Physarum polycephalum possess no neural tissue yet, despite this, are known to exhibit complex biological and computational behaviour. Given such limited resources, can…

Emerging Technologies · Computer Science 2015-11-25 Jeff Jones

We construct electronic oscillator from acellular slime mould Physarum polycephalum. The slime mould oscillator is made of two electrodes connected by a protoplasmic tube of the living slime mould. A protoplasmic tube has an average…

Emerging Technologies · Computer Science 2014-03-31 Andrew Adamatzky

Many studies have shown that Physarum polycephalum slime mold is able to find the shortest path in a maze. In this paper we study this behavior in a network, using a hyperbolic model of chemotaxis. Suitable transmission and boundary…

Numerical Analysis · Mathematics 2016-01-07 Gabriella Bretti , Roberto Natalini

Plasmodium of acellular slime mould Physarum polycephalum exhibits traits of wave-like behaviour. The plasmodium's behaviour can be finely tuned in laboratory experiments by using herbal tablets. A single tablet acts as a fixed attractor:…

Pattern Formation and Solitons · Physics 2012-12-13 Andrew Adamatzky

Decision-making is the process of selecting an action among alternatives, allowing biological and artificial systems to navigate complex environments and optimize behavior. While neural systems rely on neuron-based sensory processing and…

Biological Physics · Physics 2025-06-17 Lisa Schick , Emily Eichenlaub , Fabian Drexel , Alexander Mayer , Siyu Chen , Marcus Roper , Karen Alim

P. polycephalum may be considered as a spatially represented parallel unconventional computing substrate, but how can this `computer' be programmed? In this paper we examine and catalogue individual low-level mechanisms which may be used to…

Emerging Technologies · Computer Science 2016-10-23 Jeff Jones

In this work we study and expand a model describing the dynamics of a unicellular slime mold, Physarum Polycephalum (PP), which was proposed to simulate the ability of PP to find the shortest path connecting two food sources in a maze. The…

Numerical Analysis · Mathematics 2020-09-29 Enrico Facca , Franco Cardin , Mario Putti

Plasmodium of \emph{Physarum polycephalum} is a single cell visible by unaided eye. On a non-nutrient substrate the plasmodium propagates as a traveling localization, as a compact wave-fragment of protoplasm. The plasmodium-localization…

Pattern Formation and Solitons · Physics 2012-08-14 Andrew Adamatzky

Life evolved organisms to adapt dynamically to their environment and autonomously exhibit behaviours. While complex behaviours in organisms are typically associated with the capability of neurons to process information, the unicellular…

Biological Physics · Physics 2023-06-16 Mathieu Le Verge-Serandour , Karen Alim

A new Monte Carlo move for polymer simulations is presented. The ``wormhole'' move is build out of reptation steps and allows a polymer to reptate through a hole in space; it is able to completely displace a polymer in time N^2 (with N the…

Soft Condensed Matter · Physics 2009-11-07 J. Houdayer

Biological living materials, such as animal bones and plant stems, are able to self-heal, regenerate, adapt and make decisions under environmental pressures. Despite recent successful efforts to imbue synthetic materials with some of these…

Using a particle model of slime mould we demonstrate scoping experiments which explore how path planning may be performed by morphological adaptation. We initially demonstrate simple path planning by a shrinking blob of virtual plasmodium…

Emerging Technologies · Computer Science 2015-03-12 Jeff Jones

We report experimental laboratory studies on developing conductive pathways, or wires, using protoplasmic tubes of plasmodium of acellular slime mould Physarum polycephalum. Given two pins to be connected by a wire, we place a piece of…

Biological Physics · Physics 2013-09-17 Andrew Adamatzky

This research proposes a novel morphing structure with shells inspired by the movement of pillbugs. Instead of the pillbug body, a loopcoupled mechanism based on slider-crank mechanisms is utilized to achieve the rolling up and spreading…

Robotics · Computer Science 2025-06-06 Jieyu Wang , Yingzhong Tian , Fengfeng Xi , Damien Chablat , Jianing Lin , Gaoke Ren , Yinjun Zhao

With the advent of diffusion models, new proteins can be generated at an unprecedented rate. The motif scaffolding problem requires steering this generative process to yield proteins with a desirable functional substructure called a motif.…

Biomolecules · Quantitative Biology 2025-10-06 James Matthew Young , O. Deniz Akyildiz