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Advances in neuroscience uncover the mechanisms employed by the brain to efficiently solve complex learning tasks with very limited resources. However, the efficiency is often lost when one tries to port these findings to a silicon…

Influence functions efficiently estimate the effect of removing a single training data point on a model's learned parameters. While influence estimates align well with leave-one-out retraining for linear models, recent works have shown this…

Machine Learning · Computer Science 2022-09-13 Juhan Bae , Nathan Ng , Alston Lo , Marzyeh Ghassemi , Roger Grosse

Rich, spontaneous brain activity has been observed across a range of different temporal and spatial scales. These dynamics are thought to be important t for efficient neural functioning. Experimental evidence suggests that these neural…

Neurons and Cognition · Quantitative Biology 2015-01-21 Peter J. Hellyer , Barbara Jachs , Robert Leech , Claudia Clopath

Learning and memory relies on synapses changing their strengths in response to neural activity. However there is a substantial gap between the timescales of neural electrical dynamics (1-100 ms) and organism behaviour during learning…

Neurons and Cognition · Quantitative Biology 2023-08-08 Cian O'Donnell

Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

Neurons and Cognition · Quantitative Biology 2014-05-01 Daniel Soudry , Ron Meir

The inquiry into the origin of brain complexity remains a pivotal question in neuroscience. While synaptic stimuli are acknowledged as significant, their efficacy often falls short in elucidating the extensive interconnections of the brain…

Neurons and Cognition · Quantitative Biology 2024-04-29 Gabriel Moreno Cunha , Gillberto Corso , Matheus Phellipe Brasil de Sousa , Gustavo Zampier dos Santos Lima

Adaptive behavior, cognition and emotion are the result of a bewildering variety of brain spatiotemporal activity patterns. An important problem in neuroscience is to understand the mechanism by which the human brain's 100 billion neurons…

Neurons and Cognition · Quantitative Biology 2011-05-09 Paul Expert , Renaud Lambiotte , Dante R. Chialvo , Kim Christensen , Henrik Jeldtoft Jensen , David J. Sharp , Federico Turkheimer

Dynamic functional connectivity is an effective measure for the brain's responses to continuous stimuli. We propose an inferential method to detect the dynamic changes of brain networks based on time-varying graphical models. Whereas most…

Applications · Statistics 2020-06-23 Dingjue Ji , Junwei Lu , Yiliang Zhang , Hongyu Zhao , Siyuan Gao

Recently, adaptive control systems with relaxed persistent excitation (PE) conditions have been proposed to guarantee true parameter convergence and improve the transient response. However, in some cases, sufficient control performance and…

Systems and Control · Electrical Eng. & Systems 2025-03-03 Satoshi Tsuruhara , Kazuhisa Ito

This paper predicts the ability to externally control the firing times of a cortical neuron whose behavior follows the Izhikevich neuron model. The Izhikevich neuron model provides an efficient and biologically plausible method to track a…

Neurons and Cognition · Quantitative Biology 2020-04-24 Adam Noel , Shayan Monabbati , Dimitrios Makrakis , Andrew W. Eckford

Introduction- Identifying the potential firing patterns following different brain regions under normal and abnormal conditions increases our understanding of events at the level of neural interactions in the brain. The Izhikevich model is…

Neural and Evolutionary Computing · Computer Science 2021-03-09 Sahar Hojjatinia , Mahdi Aliyari Shoorehdeli , Zahra Fatahi , Zeinab Hojjatinia , Abbas Haghparast

Among the infinite number of possible movements that can be produced, humans are commonly assumed to choose those that optimize criteria such as minimizing movement time, subject to certain movement constraints like signal-dependent and…

Quantitative Methods · Quantitative Biology 2022-04-21 Florian Fischer , Miroslav Bachinski , Markus Klar , Arthur Fleig , Jörg Müller

Recent works have highlighted the need for a new dynamical paradigm in the modeling of brain function and evolution. Specifically, these models should incorporate non-constant and asymmetric synaptic weights $T_{ij}$ in the neuron-neuron…

Neurons and Cognition · Quantitative Biology 2025-11-03 Franco Cardin , Alberto Lovison , Amos Maritan , Aram Megighian

Biophysical models describing complex, cellular phenomena typically include systems of nonlinear differential equations with many free parameters. While experimental measurements can fix some parameters, those describing internal cellular…

Computational Physics · Physics 2025-07-08 Joseph M. Marcinik , Martín A. Toderi , Dolores Bozovic

Building a sustainable burn platform in inertial confinement fusion (ICF) requires an understanding of the complex coupling of physical processes and the effects that key experimental design changes have on implosion performance. While…

The way the brain selects and controls actions is still widely debated. Mainstream approaches based on Optimal Control focus on stimulus-response mappings that optimize cost functions. Ideomotor theory and cybernetics propose a different…

Complex systems of many interacting components exhibit patterns of recurrence and emergent behaviors in their time evolution that can be understood from a new perspective of physics of information dynamics, modeled after one such system,…

Disordered Systems and Neural Networks · Physics 2026-01-27 Uday S. Goteti , Shane A. Cybart , Robert C. Dynes

The functioning of an organ such as the brain emerges from interactions between its constituent parts. Further, this interaction is not immutable in time but rather unfolds in a succession of patterns, thereby allowing the brain to adapt to…

Neurons and Cognition · Quantitative Biology 2021-06-02 Emmanuelle Tognoli , Daniela Benites , J. A. Scott Kelso

Information about external world is delivered to the brain in the form of structured in time spike trains. During further processing in higher areas, information is subjected to a certain condensation process, which results in formation of…

Neurons and Cognition · Quantitative Biology 2015-03-17 Alexander K. Vidybida

The nervous system, more specifically, the brain, is capable of solving complex problems simply and efficiently, far surpassing modern computers. In this regard, neuromorphic engineering is a research field that focuses on mimicking the…

Neural and Evolutionary Computing · Computer Science 2022-06-13 Daniel Casanueva-Morato , Alvaro Ayuso-Martinez , Juan P. Dominguez-Morales , Angel Jimenez-Fernandez , Gabriel Jimenez-Moreno